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Reduktion kardiovaskulärer Ereignisse durch Losartan?

Die LIFE-Studie

  • Klinische Studien: LIFE
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Literatur

  1. Bruckschlegel G, Holmer SR, Jandeleit K et al. (1995) Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats. Hypertension 25: 250--259

    Google Scholar 

  2. Dahlöf B, Devereux RB, Kjeldsen SE et al. (2002) Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359: 995--1003

    Google Scholar 

  3. Hansson L, Lindholm LH, Niskanen L et al. (1999) Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. Lancet 353: 611--616

    Google Scholar 

  4. Lewis EJ, Hunsicker LG, Clarke WR et al. (2001) Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345: 851--860

    Google Scholar 

  5. Lindholm LH, Ibsen H, Dahlof B et al. (2002) Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359: 1004–1010

    Google Scholar 

  6. Sharma AM, Pischon T, Hardt S, Kunz I, Luft FC (2001) Hypothesis: β-adrenergic receptor blockers and weight gain: A systematic analysis. Hypertension 37: 250--254

    Google Scholar 

  7. SHEP Cooperative Research Group (1991) Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 265: 3255–3264

    Google Scholar 

  8. Staessen JA, Wang JG, Thijs L (2001) Cardiovascular protection and blood pressure reduction: a meta-analysis. Lancet 358: 1305–1315

    Google Scholar 

  9. Yusuf S, Sleight P, Pogue J et al. (2000) Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 342: 145--153

    Google Scholar 

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Correspondence to H. Schunkert.

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Schunkert, H. Reduktion kardiovaskulärer Ereignisse durch Losartan?. Internist 44, 367–370 (2003). https://doi.org/10.1007/s00108-003-0865-0

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  • DOI: https://doi.org/10.1007/s00108-003-0865-0

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