Low-grade (polymorphous) adenocarcinoma of the middle ear mimicking a jugulotympanic paraganglioma

(Polymorphes) Low-Grade-Adenokarzinom des Mittelohrs als Imitator eines jugulotympanalen Paraganglioms


A 64-year-old female patient presented with otalgia and hearing loss in the right ear. On otoscopy, the right tympanic membrane was highly vascularized and bulged into the anteroinferior quadrant. High-resolution computed tomography revealed an osteolytic lesion with occupation of the hypotympanum extending into the petrous apex and right parapharyngeal space as well as infiltration of the wall of the right internal carotid artery. MRI strengthened the suspicion of a jugulotympanic paraganglioma. The biopsy material obtained through exploratory tympanotomy was assessed as a low-grade polymorphic adenocarcinoma. The tumor was treated with definitive chemoradiotherapy. Posttherapeutic imaging after 4 months did not show any evidence of tumor progression.

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Correspondence to Konstantinos Mantsopoulos PhD, MD.

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K. Mantsopoulos, L. Taha, R. Fietkau, J. Hornung, A. Agaimy and H. Iro declare that they have no competing interests.

For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case. Additional written informed consent was obtained from all individual participants or their legal representatives for whom identifying information is included in this article.

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Mantsopoulos, K., Taha, L., Fietkau, R. et al. Low-grade (polymorphous) adenocarcinoma of the middle ear mimicking a jugulotympanic paraganglioma. HNO (2021). https://doi.org/10.1007/s00106-021-01028-x

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  • Otologic surgical procedures
  • Salivary gland diseases
  • Tympanic membrane
  • Radiotherapy
  • Antineoplastic agents