Low-grade (polymorphous) adenocarcinoma of the middle ear mimicking a jugulotympanic paraganglioma

(Polymorphes) Low-Grade-Adenokarzinom des Mittelohrs als Imitator eines jugulotympanalen Paraganglioms

Abstract

A 64-year-old female patient presented with otalgia and hearing loss in the right ear. On otoscopy, the right tympanic membrane was highly vascularized and bulged into the anteroinferior quadrant. High-resolution computed tomography revealed an osteolytic lesion with occupation of the hypotympanum extending into the petrous apex and right parapharyngeal space as well as infiltration of the wall of the right internal carotid artery. MRI strengthened the suspicion of a jugulotympanic paraganglioma. The biopsy material obtained through exploratory tympanotomy was assessed as a low-grade polymorphic adenocarcinoma. The tumor was treated with definitive chemoradiotherapy. Posttherapeutic imaging after 4 months did not show any evidence of tumor progression.

This is a preview of subscription content, access via your institution.

Fig. 1
Fig. 2
Fig. 3

References

  1. 1.

    Mimouni O, Sanjuan M, Giusiano S, Lavieille JP, Magnan J, Deveze A (2010) Mucoepidermoid carcinoma arising from the middle ear: a rare histopathologic condition. Otol Neurotol 31:858–860

    Article  Google Scholar 

  2. 2.

    Magliulo G, Vingolo GM, Cristofari P, Natale AS (1993) Primary adenoid cystic carcinoma of the middle ear and mastoid. Acta Otorhinolaryngol Belg 47:39–42

    CAS  PubMed  Google Scholar 

  3. 3.

    Ruiz-Godoy L, Suarez L, Mosqueda A, Meneses A (2007) Polymorphous low-grade adenocarcinoma of the parotid gland. Case report and review of the literature. Med Oral Patol Oral Cir Bucal 12:E30–E33

    CAS  PubMed  Google Scholar 

  4. 4.

    Charous DD, Cunnane MF, Rosen MR, Keane WM (2005) Recurrent polymorphous low-grade adenocarcinoma manifesting as a sinonasal mass: a case report. Ear Nose Throat J 84:354–356–357

    Article  Google Scholar 

  5. 5.

    Wang CH, Li YY, Han FY (2011) Polymorphous low-grade adenocarcinoma of ear: one case report. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 46:156–157

    PubMed  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Konstantinos Mantsopoulos PhD, MD.

Ethics declarations

Conflict of interest

K. Mantsopoulos, L. Taha, R. Fietkau, J. Hornung, A. Agaimy and H. Iro declare that they have no competing interests.

For this article no studies with human participants or animals were performed by any of the authors. All studies performed were in accordance with the ethical standards indicated in each case. Additional written informed consent was obtained from all individual participants or their legal representatives for whom identifying information is included in this article.

The supplement containing this article is not sponsored by industry.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Mantsopoulos, K., Taha, L., Fietkau, R. et al. Low-grade (polymorphous) adenocarcinoma of the middle ear mimicking a jugulotympanic paraganglioma. HNO (2021). https://doi.org/10.1007/s00106-021-01028-x

Download citation

Keywords

  • Otologic surgical procedures
  • Salivary gland diseases
  • Tympanic membrane
  • Radiotherapy
  • Antineoplastic agents