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Perioperative Antibiotikaprophylaxe in der HNO

Prophylactic antibiotic use in ENT surgery

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Zusammenfassung

Die perioperative Antibiotikaprophylaxe (POAP) verfolgt im Gegensatz zur therapeutischen Gabe von Antibiotika nicht das Ziel, eine definierte Infektion zu bekämpfen. Es soll vielmehr verhindert werden, dass Keime, die in den meisten Fällen zur physiologischen Normalflora gehören, im Gebiet des Hautschnitts bzw. des operativen Zugangswegs ins Gewebe eindringen und sich dort ansiedeln können. Die Frage, bei welchem spezifischen Eingriff und bei welchem Patienten eine POAP sinnvoll ist, kann im Fachbereich der HNO-Heilkunde allerdings nur zum Teil mithilfe experimenteller Daten beantwortet werden. Ziel dieser Arbeit war es, die aktuelle Literatur nach Empfehlungen zur antibiotischen Prophylaxe im HNO-Bereich zu analysieren und auf der Basis der gefundenen Arbeiten einen rationalen Standard zu entwickeln.

Abstract

Surgical antibiotic prophylaxis (SAP) is defined as the administration of an antimicrobial agent prior to contamination in previously sterile spaces and fluid. SAP should not be confused with the therapeutic use of antibiotics. There are a growing number of studies with the goal of answering the question which patients benefit most from SAP during which specific surgical procedure. However, in the specific surgical field of head and neck surgery and otolaryngological surgery, there are only a few guidelines answering that question for specific procedures. The aim of this study was to analyze the evidence found in the literature and to develop a standard operating procedure, which specifically addresses head and neck and otolaryngeal surgical procedures.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. C. Thorn, A. Faber, J.D. Schultz, K. Hörmann und B.A. Stuck geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Authors and Affiliations

  1. Universitäts-HNO-Klinik Mannheim der Universität Heidelberg, Theodor-Kutzer-Ufer 1–3, 68157, Mannheim, Deutschland

    C. Thorn, A. Faber, J.D. Schultz, K. Hörmann & B.A. Stuck

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  1. C. Thorn
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  2. A. Faber
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  3. J.D. Schultz
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  4. K. Hörmann
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  5. B.A. Stuck
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Correspondence to C. Thorn.

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Thorn, C., Faber, A., Schultz, J. et al. Perioperative Antibiotikaprophylaxe in der HNO. HNO 63, 118–124 (2015). https://doi.org/10.1007/s00106-014-2946-x

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