Zusammenfassung
Hintergrund
Durch verbesserte Operationstechniken kann der Kehlkopf heute bei Kopf-Hals-Tumoren oft erhalten bleiben, jedoch nicht unbedingt die Schluckfunktion. Die Studie untersucht Ausprägung und Prädiktoren von Schluckstörungen nach Kehlkopfteilresektion.
Patienten und Methoden
In einer multizentrischen Querschnittsstudie (n=154) wurde bei kehlkopfteilresezierten Patienten die Auftrittshäufigkeit von Schluckstörungen und Problemen beim Essen erhoben. Zusätzlich wurden soziodemographische, krankheits- und behandlungsbezogene Daten sowie Alkohol- und Nikotinkonsum erfasst.
Ergebnisse
80% der Studienteilnehmer haben keine Probleme mit dem Schlucken und dem Essen. Die Wahrscheinlichkeit von Schluckstörungen ist signifikant niedriger nach Laseroperationen [Odds Ratio (OR): 0,12; 95%-Konfidenzintervall (95%-KI): 0,04–0,37; p<0,01], wenn die Operation länger zurückliegt (OR=0,89; 95%-KI: 0,75–0,99; p<0,03) und wenn die Patienten nicht rauchen (OR=3,39; 95%-KI: 1,29–8,94; p<0,02).
Schlussfolgerung
Postoperatives Rauchen steht mit Schluckstörungen in Zusammenhang und sollte daher in Arzt- und Therapeutengesprächen thematisiert werden.
Abstract
Background
Improvements in surgical techniques have led to a higher percentage of larynx preservations. These do not always include preservation of the swallowing function. This study investigates the prevalence of swallowing disorders after partial laryngectomy and their predictors.
Patients and methods
In a multicenter cross-sectional study with patients who received a partial laryngectomy (n=154) the prevalences of problems related to swallowing and eating were gathered. Additionally, medical and sociodemographic data were obtained as well as information about alcohol and tobacco consumption.
Results
Twenty percent of the patients had problems related to swallowing and eating; more specifically, eating solid foods and eating in public. Chances of having swallowing disorders were significantly lower for patients who received laser therapy (OR=0.12; 95% CI: 0.04–0.37; p<0.01), when time since the last laryngeal surgery was longer (OR=0.89; 95% CI: 0.75–0.99; p<0.03) and when patients were non-smokers (OR=3.39; 95% CI: 1.29–8.94; p<0.02).
Conclusion
Swallowing disorders correlate with post-surgery smoking. Physicians and therapists should focus more on the negative side effects of smoking on swallowing during patient consultations.
Literatur
Benninger MS, Gillen J, Thieme P et al (1994) Factors associated with recurrence and voice quality following radiation therapy for T1 and T2 glottic carcinomas. Laryngoscope 104(3 Pt 1)294–298
Bentzen M, Trotti A (2007) Evaluation of early and late toxicities in chemo radiation trials. J Clin Oncol 25(26):4096–4103
Bindewald J, Herrmann E, Dietz A et al (2007) Quality of life and voice intelligibility in laryngeal cancer patients – relevance of the satisfaction paradox. LRO 86(6):426–430
Björdal K, Graeff A de (2000) A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. Eur J Cancer 36:1796–1807
Burger M, Brönstrup A, Pietrzik K (2004) Derivation of tolerable upper alcohol levels in Germany: a systematic review of risks and benefits of moderate alcohol consumption. Prev Med 39:111–127
Dietz A, Meyer A, Singer S (2009) Lebensqualitätsmessungen bei Patienten mit Kopf-Hals-Malignomen: Aktueller Stand und zukünftige Anforderungen. HNO 57:857–865
Dietz A, Boehm A, Wichmann G et al (2012) Multimodal laryngeal preservation: Current data-based opinion. HNO 60(1):19–31
Eckel HE (2012) Recent advances in the treatment of laryngeal and hypopharyngeal carcinoma. HNO 60(1):6–18
Dietzsch S, Melzer R, Boehm A et al (2011) Schluckstörungen nach Kopf-Hals-Tumortherapie und die Möglichkeiten der IMRT. LRO 90(2):657–662
Duffy SA, Ronis DL, Valenstein S et al (2007) Depressive symptoms, smoking, drinking, and quality of life among head and neck cancer patients. Psychosomatics 48:142–148
Fabian MC, Irish JC, Brown DH et al (1996) Tobacco, alcohol, and oral cancer: the patient’s perspective. J Otolaryngol 25:88–93
Gritz ER, Carmack CL, Moor C de et al (1999) First year after head and neck cancer: quality of life. J Clin Oncol 17:352–360
Gritz ER, Vidrine DJ, Lazev AB (2003) Smoking cessation in cancer patients: never too late to quit. In: Given CW, Given B, Champion V et al (eds) Evidence-based cancer care and prevention: behavioral interventions. Springer, New York, S 107–140
Hammerlid E, Bjordal K, Ahlner-Elmqvist M et al (2001) A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis. Laryngoscope 111:669–680
Ledeboer QCP, Velden LA van der, Boer MF de et al (2005) Physical and psychosocial correlates of head and neck cancer: an update of the literature and challenges for the future (1996–2003). Clin Otolaryngol 30:303–319
List MA, Ritter-Sterr CA, Baker TM et al (1996) Longitudinal assessment of quality of life in laryngeal cancer patients. Head Neck 18:1–10
Locher JL, Robinson CO, Bailey FA et al (2010) Disruptions in the organization of meal preparation and consumption among older cancer patients and their family caregivers. Psychooncology 19:967–974
Olthoff A, Steuer-Vogt MK, Licht K et al (2006) Quality of life after treatment for laryngeal carcinomas. Eur Arch Otorhinolaryngol 68(5):253–258
Osthus AA, Aarstadn AKH, Olofsson J et al (2011) Head and neck specific Health Related Quality of Life scores predict subsequent survival in successfully treated head and neck cancer patients: A prospective cohort study. Oral Oncol 47(10):974–979
Pantel M, Guntinas-Lichius O (2012) Laryngeal carcinoma: Epidemiology, risk factors and survival. HNO 60(1):32–40
Ramírez MJ, Ferriol EE, Domenech FG et al (2003) Psychosocial adjustment in patients surgically treated for laryngeal cancer. Otolaryngol Head Neck Surg 129(1):92–97
Remacle M, Eckel HE, Antonelli A et al (2000) Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. Eur Arch Otorhinolaryngol 257:227–231
Robert Koch-Institut (2011) Krebs in Deutschland 2005/06. Häufigkeiten und Trends. http://www.rki.de
Rogers SN, Ahad SA, Murphy AP (2007) A structured review and theme analysis of papers published on ‚quality of life‘ in head and neck cancer: 2000–2005. Oral Oncol 43:843–868
Roh J-L, Dong-Hyun K, Sang YK et al (2007) Quality of life and voice in patients after laser cordectomy for Tis and T1 glottic carcinoma. Head Neck 10:1010–1016
Sewnaik A, Brink JL van den, Wieringa MH et al (2005) Surgery for recurrent laryngeal carcinoma after radiotherapy: Partial laryngectomy or total laryngectomy for a better quality of life? Otolaryngol Head Neck Surg 132:95–98
Singer S, Keszte J, Thiele A et al (2010) Rauchverhalten nach Laryngektomie. LRO 89(3)146–150
Singer S, Wollbrück D, Wulke C et al (2009) Validation of the EORTC QLQ-C30 and EORTC QLQ-H&N35 in patients with laryngeal cancer after surgery. Head Neck 31(1):64–76
Terrell JE, Fisher SG, Wolf GT (1998) Long-term quality of life after treatment of laryngeal cancer: The Veterans Affairs Laryngeal Cancer Study Group. Arch Otolaryngol Head Neck Surg 124:964–971
Terrell JF, Ronis DL, Fowler KF et al (2004) Clinical predictors of quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 130:401–408
Tsoh JY, Humfleet GL, Munoz RF et al (2000) Development of major depression after treatment for smoking cessation. Am J Psychiatry 157:368–374
Verband deutscher Rentenversicherungsträger (1999) Förderschwerpunkt „Rehabilitationswissenschaften“. Empfehlungen der Arbeitsgruppen „Generische Methoden“, „Routinedaten“ und „Reha-Ökonomie“. DRV-Schriften, VDR, Frankfurt am Main
Yazici ZM, Sayin I, Kayhan FT et al (2010) Laryngopharyngeal reflux might play a role on chronic nonspecific pharyngitis. Eur Arch Otorhinolaryngol 267(4):863–869
Interessenkonflikt
Die korrespondierende Autorin gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Additional information
Gefördert durch die Universität Leipzig, NBL 3– Förderung 1. Forschungsprogramm der Medizinischen Fakultät Leipzig (formel.1), Projektnummer formel.1–57
Rights and permissions
About this article
Cite this article
Meyer, A. Schluckstörungen nach Kehlkopfteilresektion. HNO 60, 892–900 (2012). https://doi.org/10.1007/s00106-012-2519-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00106-012-2519-9