Literatur
Adam P, Stiffman M, Blake RL Jr (1998) A clinical trial of hypertonic saline nasal spray in subjects with the common cold or rhinosinusitis. Arch Fam Med 7:39–43
Ahovuo-Saloranta A, Borisenko OV, Kovanen N et al (2008) Antibiotics for acute maxillary sinusitis. Cochrane Database Syst Rev:CD000243 (EL Ia)
Alkire BC, Bhattacharyya N (2010) An assessment of sinonasal anatomic variants potentially associated with recurrent acute rhinosinusitis. Laryngoscope 120(3):631–634
American Thoracic Society Workshop (1999) American Thoracic Society Workshop. Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options. Am J Respir Crit Care Med 160:1778–1787
Anand VK (2004) Epidemiology and economic impact of rhinosinusitis. Ann Otol Rhinol Laryngol Suppl 193:3–5
Anzai Y, Weymuller EA Jr, Yueh B et al (2004) The impact of sinus computed tomography on treatment decisions for chronic sinusitis. Arch Otolaryngol Head Neck Surg 130:423–428
Ashraf N, Bhattacharyya N (2001) Determination of the „incidental“ Lund score for the staging of chronic rhinosinusitis. Otolaryngol Head Neck Surg 125:483–486
AWMF (2001) Das Leitlinien-Manual von AWMF und ÄZQ. Z Ärztl Fortbild Qualitätssich 95:1–84
AWMF (2009) Leitlinien der Deutschen Röntgengesellschaft. Gesichtsschädel: Entzündungen. AWMF Leitlinienregister Nr. 039/037
Bachar G, Barker E, Nithiananthan S et al (2009) Three-dimensional tomosynthesis and cone-beam computed tomography: an experimental study for fast, low-dose intraoperative imaging technology for guidance of sinus and skull base surgery. Laryngoscope 119:434–441
Bachert C, Gevaert P, Holtappels G et al (2001) Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 107:607–614
Bachert C, Gevaert P, Howarth P et al (2003) IgE to Staphylococcus aureus enterotoxins in serum is related to severity of asthma. J Allergy Clin Immunol 111:1131–1132
Bachert C, Patou J, Van Cauwenberge P (2006) The role of sinus disease in asthma. Curr Opin Allergy Clin Immunol 6:29–36
Bachert C, Schapowal A, Funk P et al (2009) Treatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: a randomized, double-blind, placebo-controlled trial. Rhinology 47:51–58
Bachert C, Van Bruaene N, Toskala E et al (2009) Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis – a GALEN study. Allergy 64:520–533
Bachert C, Wagenmann M, Hauser U et al (1997) IL-5 synthesis is upregulated in human nasal polyp tissue. J Allergy Clin Immunol 99:837–842
Bachert C, Wagenmann M, Rudack C et al (1998) The role of cytokines in infectious sinusitis and nasal polyposis. Allergy 53:2–13
Bachmann G, Hommel G, Michel O (2000) Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease. Eur Arch Otorhinolaryngol 257:537–541
Badia L, Lund V (2001) Topical corticosteroids in nasal polyposis. Drugs 61:573–578
Baenkler HW (2008) Salicylate intolerance: pathophysiology, clinical spectrum, diagnosis and treatment. Dtsch Arztebl Int 105:137–142
Bajaj Y, Sethi N, Carr S et al (2009) Endoscopic sinus surgery as day-case procedure. J Laryngol Otol 123:619–622
Bauchau V, Durham SR (2004) Prevalence and rate of diagnosis of allergic rhinitis in Europe. Eur Respir J 24:758–764
Baumann I, Blumenstock G, Zalaman IM et al (2007) Impact of gender, age, and comorbidities on quality of life in patients with chronic rhinosinusitis. Rhinology 45:268–272
Bayonne E, Kania R, Tran P et al (2009) Intracranial complications of rhinosinusitis. A review, typical imaging data and algorithm of management. Rhinology 47:59–65
Becker SS, Bomeli SR, Gross CW et al (2006) Limits of endoscopic visualization and instrumentation in the frontal sinus. Otolaryngol Head Neck Surg 135:917–921
Behrbohm H, Kaschke O, Sydow K (1995) Der Einfluss des pflanzlichen Sekretolytikums Gelomyrtol forte auf die mukoziliäre Clearance der Kieferhöhle. Laryngorhinootologie 74:733–737
Benninger MS, Ferguson BJ, Hadley JA et al (2003) Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 129:1–32
Benninger MS, Payne SC, Ferguson BJ et al (2006) Endoscopically directed middle meatal cultures versus maxillary sinus taps in acute bacterial maxillary rhinosinusitis: a meta-analysis. Otolaryngol Head Neck Surg 134:3–9 (EL Ia)
Benninger MS, Sedory Holzer SE, Lau J (2000) Diagnosis and treatment of uncomplicated acute bacterial rhinosinusitis: summary of the Agency for Health Care Policy and Research evidence-based report. Otolaryngol Head Neck Surg 122:1–7
Berg O, Carenfelt C (1988) Analysis of symptoms and clinical signs in the maxillary sinus empyema. Acta Otolaryngol 105:343–349
Berg O, Carenfelt C (1985) Etiological diagnosis in sinusitis: ultrasonography as clinical complement. Laryngoscope 95:851–853
Berg O, Carenfelt C, Kronvall G (1988) Bacteriology of maxillary sinusitis in relation to character of inflammation and prior treatment. Scand J Infect Dis 20:511–516
Berg O, Carenfelt C, Rystedt G et al (1986) Occurrence of asymptomatic sinusitis in common cold and other acute ENT-infections. Rhinology 24:223–225
Berges-Gimeno MP, Simon RA, Stevenson DD (2003) Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 111:180–186
Bhattacharyya N (2010) Ambulatory sinus and nasal surgery in the United States: demographics and perioperative outcomes. Laryngoscope 120:635–638
Bhattacharyya N (2009) Contemporary assessment of the disease burden of sinusitis. Am J Rhinol Allergy 23:392–395
Bhattacharyya N (2003) The economic burden and symptom manifestations of chronic rhinosinusitis. Am J Rhinol 17:27–32
Bhattacharyya N (1999) Test-retest reliability of computed tomography in the assessment of chronic rhinosinusitis. Laryngoscope 109:1055–1058
Bousquet J, Bachert C, Canonica GW et al (2009) Unmet needs in severe chronic upper airway disease (SCUAD). J Allergy Clin Immunol 124:428–433
Bousquet J, Khaltaev N, Cruz AA et al (2008) Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 63(Suppl 86):8–160
Braun JJ, Alabert JP, Michel FB et al (1997) Adjunct effect of loratadine in the treatment of acute sinusitis in patients with allergic rhinitis. Allergy 52:650–655
Braunstahl GJ (2007) The united airways concept: from bench to bedside. Monaldi Arch Chest Dis 67:95–101
Bresciani M, Paradis L, Des Roches A et al (2001) Rhinosinusitis in severe asthma. J Allergy Clin Immunol 107:73–80
Brook I (2001) Sinusitis – overcoming bacterial resistance. Int J Pediatr Otorhinolaryngol 58:27–36
Brook I, Thompson DH, Frazier EH (1994) Microbiology and management of chronic maxillary sinusitis. Arch Otolaryngol Head Neck Surg 120:1317–1320
Brook I, Yocum P, Frazier EH (1996) Bacteriology and beta-lactamase activity in acute and chronic maxillary sinusitis. Arch Otolaryngol Head Neck Surg 122:418–422 (discussion 423)
Browne JP, Hopkins C, Slack R et al (2006) Health-related quality of life after polypectomy with and without additional surgery. Laryngoscope 116:297–302
Bucher HC, Tschudi P, Young J et al (2003) Effect of amoxicillin-clavulanate in clinically diagnosed acute rhinosinusitis: a placebo-controlled, double-blind, randomized trial in general practice. Arch Intern Med 163:1793–1798
Bugten V, Nordgard S, Steinsvag S (2006) The effects of debridement after endoscopic sinus surgery. Laryngoscope 116:2037–2043
Bugten V, Nordgard S, Steinsvag S (2008) Long-term effects of postoperative measures after sinus surgery. Eur Arch Otorhinolaryngol 265:531–537
Burke TF, Guertler AT, Timmons JH (1994) Comparison of sinus x-rays with computed tomography scans in acute sinusitis. Acad Emerg Med 1:235–239
Canonica GW, Bousquet J, Mullol J et al (2007) A survey of the burden of allergic rhinitis in Europe. Allergy 62(Suppl 85):17–25
Casiano RR (1997) Correlation of clinical examination with computer tomography in paranasal sinus disease. Am J Rhinol 11:193–196
Cervin A, Kalm O, Sandkull P et al (2002) One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide. Otolaryngol Head Neck Surg 126:481–489
Cervin A, Wallwork B (2009) Macrolides and their role in the treatment of CRS. In: Stucker F (ed) Rhinology and Facial Plastic Surgery. Springer, New York, p 295–303
Chakrabarti A, Denning DW, Ferguson BJ et al (2009) Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope 119:1809–1818
Chalton R, Mackay I, Wilson R et al (1985) Double blind, placebo controlled trial of betamethasone nasal drops for nasal polyposis. Br Med J (Clin Res Ed) 291:788
Chen Y, Dales R, Lin M (2003) The epidemiology of chronic rhinosinusitis in Canadians. Laryngoscope 113:1199–1205
Cherry DK, Woodwell DA, Rechtsteiner EA (2007) National Ambulatory Medical Care Survey: 2005 summary. Adv Data:1–39
Chester AC, Antisdel JL, Sindwani R (2009) Symptom-specific outcomes of endoscopic sinus surgery: a systematic review. Otolaryngol Head Neck Surg 140:633–639
Chester AC, Sindwani R, Smith TL et al (2008) Fatigue improvement following endoscopic sinus surgery: a systematic review and meta-analysis. Laryngoscope 118:730–739
Chester AC, Sindwani R, Smith TL et al (2008) Systematic review of change in bodily pain after sinus surgery. Otolaryngol Head Neck Surg 139:759–765
Church CA, Chiu AG, Vaughan WC (2003) Endoscopic repair of large skull base defects after powered sinus surgery. Otolaryngol Head Neck Surg 129:204–209
Clayman GL, Adams GL, Paugh DR et al (1991) Intracranial complications of paranasal sinusitis: a combined institutional review. Laryngoscope 101:234–239
Coffey CS, Sonnenburg RE, Melroy CT et al (2006) Endoscopically guided aerobic cultures in postsurgical patients with chronic rhinosinusitis. Am J Rhinol 20:72–76
Cohen AN, Wang MB (2007) Minitrephination as an adjunctive measure in the endoscopic management of complex frontal sinus disease. Am J Rhinol 21:629–636
Cohen M, Kofonow J, Nayak JV et al (2009) Biofilms in chronic rhinosinusitis: a review. Am J Rhinol Allergy 23:255–260
Cohen NA, Kennedy DW (2006) Revision endoscopic sinus surgery. Otolaryngol Clin North Am 39:417–435, vii
Collins JG (1997) Prevalence of selected chronic conditions: United States, 1990–1992. Vital Health Stat 10:1–89
Corriveau MN, Zhang N, Holtappels G et al (2009) Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization. Am J Rhinol Allergy 23:461–465
Cutler JL, Duncavage JA, Matheny K et al (2003) Results of Caldwell-Luc after failed endoscopic middle meatus antrostomy in patients with chronic sinusitis. Laryngoscope 113:2148–2150
Dalziel K, Stein K, Round A et al (2006) Endoscopic sinus surgery for the excision of nasal polyps: A systematic review of safety and effectiveness. Am J Rhinol 20:506–519
Dalziel K, Stein K, Round A et al (2003) Systematic review of endoscopic sinus surgery for nasal polyps. Health Technol Assess 7:1–159, iii
Dammann F (2007) Bildgebung der Nasennebenhohlen (NNH) in der heutigen Zeit. Radiologe 47:576, 578–583
Bock GH de, Dekker FW, Stolk J et al (1997) Antimicrobial treatment in acute maxillary sinusitis: a meta-analysis. J Clin Epidemiol 50:881–890 (EL Ia)
Bock GH de, Houwing-Duistermaat JJ, Springer MP et al (1994) Sensitivity and specificity of diagnostic tests in acute maxillary sinusitis determined by maximum likelihood in the absence of an external standard. J Clin Epidemiol 47:1343–1352
Ferranti SD de, Ioannidis JP, Lau J et al (1998) Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis. BMJ 317:632–637 (EL Ia)
DeShazo RD, O’Brien M, Chapin K et al (1997) Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 99:475–485
Desrosiers M, Ferguson B, Klossek J et al (2006) Clinical efficacy, time to symptom resolution, and tolerability of telithromycin vs amoxicillin-clavulanate in acute bacterial sinusitis. In: Abstracts of the 46th international conference on antimicrobial agents and chemotherapy. San Francisco, CA, USA, p Abstract L-1448
Deuschl H, Drettner B (1977) Nasal polyps treated by beclomethasone nasal aerosol. Rhinology 15:17–23
Dixon AE (2009) Rhinosinusitis and asthma: the missing link. Curr Opin Pulm Med 15:19–24
Dolor RJ, Witsell DL, Hellkamp AS et al (2001) Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. JAMA 286:3097–3105
Douglas RM, Hemila H, D’Souza R et al (2004) Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev:CD000980
Draf W (1991) Endonasal micro-endoscopic frontal sinus surgery, the Fulda concept. Oper Tech Otolaryngol Head Neck Surg 2:234–240
Dubin MG, Kuhn FA, Melroy CT (2007) Radiographic resolution of chronic rhinosinusitis without polyposis after 6 weeks vs 3 weeks of oral antibiotics. Ann Allergy Asthma Immunol 98:32–35
Durr DG, Desrosiers MY, Dassa C (2001) Impact of rhinosinusitis in health care delivery: the Quebec experience. J Otolaryngol 30:93–97
Dykewicz MS, Hamilos DL (2010) Rhinitis and sinusitis. J Allergy Clin Immunol 125:103–115
Ebbens FA, Scadding GK, Badia L et al (2006) Amphotericin B nasal lavages: not a solution for patients with chronic rhinosinusitis. J Allergy Clin Immunol 118:1149–1156
Eccles R, Jawad MS, Morris S (1990) The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J Pharm Pharmacol 42:652–654
Eggers G, Klein J, Welzel T et al (2008) Geometric accuracy of digital volume tomography and conventional computed tomography. Br J Oral Maxillofac Surg 46:639–644
Eggesbo HB (2006) Radiological imaging of inflammatory lesions in the nasal cavity and paranasal sinuses. Eur Radiol 16:872–888
Eichner KG, Wimmer M (1987) Zur Akupunkturbehandlung bei Kindern und Erwachsenen. Akupunktur Theorie und Praxis 15:6–14
Elies W, Bestehorn M, Thate-Waschke I (2007) Häufigkeit und Therapie der Sinusitis Chemotherapie Journal 16:167–175
Engels EA, Terrin N, Barza M et al (2000) Meta-analysis of diagnostic tests for acute sinusitis. J Clin Epidemiol 53:852–862
Esposito S, Bosis S, Bellasio M et al (2007) From clinical practice to guidelines: how to recognize rhinosinusitis in children. Pediatr Allergy Immunol 18(Suppl 18):53–55
Federspil P (2009) Antibiotikatherapie der Infektionen an Kopf und Hals. Konsensusbericht, im Auftrag des Präsidiums der Deutschen Gesellschaft fur Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. Laryngorhinootologie 88:329–338
Federspil P, Federspil PA (2005) Antibiotikatherapie in der Hals-Nasen-Ohren-Heilkunde. HNO 53:11–28
Federspil P, Elies W, Luckhaupt H et al (2003) Leitlinien zur Antibiotika-Therapie der bakteriellen Infektionen an Kopf und Hals. Arzneimitteltherapie 21:162–175
Federspil P, Wulkow R, Zimmermann T (1997) Wirkung von Myrtol standardisiert bei der Therapie der akuten Sinusitis – Ergebnisse einer doppelblinden, randomisierten Multicenterstudie gegen Plazebo. Laryngorhinootologie 76:23–27 (EL Ib)
Felisati G, Ramadan H (2007) Rhinosinusitis in children: the role of surgery. Pediatr Allergy Immunol 18(Suppl 18):68–70
Filiaci F, Passali D, Puxeddu R et al (2000) A randomized controlled trial showing efficacy of once daily intranasal budesonide in nasal polyposis. Rhinology 38:185–190
Fokkens W, Lund V, Bachert C et al (2005) EAACI position paper on rhinosinusitis and nasal polyps executive summary. Allergy 60:583–601
Fokkens W, Lund V, Mullol J et al (2007) European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl (20):1–136
Foreman A, Psaltis AJ, Tan LW et al (2009) Characterization of bacterial and fungal biofilms in chronic rhinosinusitis. Am J Rhinol Allergy 23:556–561
Foreman A, Singhal D, Psaltis AJ et al (2010) Targeted imaging modality selection for bacterial biofilms in chronic rhinosinusitis. Laryngoscope 120:427–431
Foreman A, Wormald PJ (2010) Different biofilms, different disease? A clinical outcomes study. Laryngoscope 120:1701–1706
Fox RW, Lockey RF (2003) The impact of rhinosinusitis on asthma. Curr Allergy Asthma Rep 3:513–518
Fried MP, Moharir VM, Shin J et al (2002) Comparison of endoscopic sinus surgery with and without image guidance. Am J Rhinol 16:193–197
Fried MP, Sadoughi B, Gibber MJ et al (2010) From virtual reality to the operating room: the endoscopic sinus surgery simulator experiment. Otolaryngol Head Neck Surg 142:202–207
Friese KH, Zabalotnyi DI (2007) Homoopathie bei akuter Rhinosinusitis: Eine doppelblinde, placebokontrollierte Studie belegt die Wirksamkeit und Vertraglichkeit eines homoopathischen Kombinationsarzneimittels. HNO 55:271–277
Gaga M, Lambrou P, Papageorgiou N et al (2000) Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis. Clin Exp Allergy 30:663–669
Gallagher RM, Gross CW, Phillips CD (1998) Suppurative intracranial complications of sinusitis. Laryngoscope 108:1635–1642
Gevaert P, Claeys S, Bachert C (2009) ESS for nasal polyposis. In: Stucker F (ed) Rhinology and Facial Plastic Surgery. Springer, New York, p 593–599
Gevaert P, Holtappels G, Johansson SG et al (2005) Organization of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue. Allergy 60:71–79
Gliklich RE, Metson R (1998) Economic implications of chronic sinusitis. Otolaryngol Head Neck Surg 118:344–349
Gliklich RE, Metson R (1995) The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol Head Neck Surg 113:104–109
Gold SM, Tami TA (1997) Role of middle meatus aspiration culture in the diagnosis of chronic sinusitis. Laryngoscope 107:1586–1589
Gosepath J, Hoffmann F, Schafer D et al (1999) Aspirin intolerance in patients with chronic sinusitis. ORL J Otorhinolaryngol Relat Spec 61:146–150
Gosepath J, Pogodsky T, Mann WJ (2008) Characteristics of recurrent chronic rhinosinusitis after previous surgical therapy. Acta Otolaryngol 128:778–784
Graham SM, Nerad JA (2003) Orbital complications in endoscopic sinus surgery using powered instrumentation. Laryngoscope 113:874–878
Grosjean P, Weber R (2007) Fungus balls of the paranasal sinuses: a review. Eur Arch Otorhinolaryngol 264:461–470
Gwaltney JM (1994) Microbiology of sinusitis. In: Druce HM (ed) Sinusitis: Pathophysiology and Treatment (Clinical Allergy and Immunology Series). Marcel Dekker, New York
Gwaltney JM Jr, Jones JG, Kennedy DW (1995) Medical management of sinusitis: educational goals and management guidelines. The International Conference on sinus Disease. Ann Otol Rhinol Laryngol Suppl 167:22–30
Gwaltney JM Jr, Phillips CD, Miller RD et al (1994) Computed tomographic study of the common cold. N Engl J Med 330:25–30
Gwaltney JM Jr, Wiesinger BA, Patrie JT (2004) Acute community-acquired bacterial sinusitis: the value of antimicrobial treatment and the natural history. Clin Infect Dis 38:227–233
Hackman TG, Ferguson BJ (2005) Powered instrumentation and tissue effects in the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg 13:22–26
Hahn S, Palmer JN, Purkey MT et al (2009) Indications for external frontal sinus procedures for inflammatory sinus disease. Am J Rhinol Allergy 23:342–347
Han DH, An SY, Kim SW et al (2007) Primary and secondary fungal infections of the paranasal sinuses: clinical features and treatment outcomes. Acta Otolaryngol Suppl:78–82
Hansen JG, Schmidt H, Rosborg J et al (1995) Predicting acute maxillary sinusitis in a general practice population. BMJ 311:233–236
Hartwig S, Linden M, Laurent C et al (1988) Budesonide nasal spray as prophylactic treatment after polypectomy (a double blind clinical trial). J Laryngol Otol 102:148–151
Harvey R, Hannan SA, Badia L et al (2007) Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Cochrane Database Syst Rev:CD006394
Hashiba M, Baba S (1996) Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. Acta Otolaryngol Suppl 525:73–78
Healy DY, Leid JG, Sanderson AR et al (2008) Biofilms with fungi in chronic rhinosinusitis. Otolaryngol Head Neck Surg 138:641–647
Heatley DG, McConnell KE, Kille TL et al (2001) Nasal irrigation for the alleviation of sinonasal symptoms. Otolaryngol Head Neck Surg 125:44–48
Hedman J, Kaprio J, Poussa T et al (1999) Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study. Int J Epidemiol 28:717–722
Heikkinen T, Jarvinen A (2003) The common cold. Lancet 361:51–59
Hellquist HB (1996) Nasal polyps update. Histopathology. Allergy Asthma Proc 17:237–242
Hissaria P, Smith W, Wormald PJ et al (2006) Short course of systemic corticosteroids in sinonasal polyposis: a double-blind, randomized, placebo-controlled trial with evaluation of outcome measures. J Allergy Clin Immunol 118:128–133 (EL Ib)
Hochstim CJ, Choi JY, Lowe D et al (2010) Biofilm detection with hematoxylin-eosin staining. Arch Otolaryngol Head Neck Surg 136:453–456
Holmberg K, Juliusson S, Balder B et al (1997) Fluticasone propionate aqueous nasal spray in the treatment of nasal polyposis. Ann Allergy Asthma Immunol 78:270–276
Holzmuller A, Gudziol H, Muller A (2009) Lebensqualität nach funktionell-endoskopischer Nasennebenhöhlen-Operation bei Polyposis nasi (Eine Langzeitstudie). Laryngorhinootologie 88:174–180
Hopkins C, Browne J, Slack R et al (2007) Variation in day-case nasal surgery – why cannot we improve our day-case rates? Clin Otolaryngol 32:12–18
Hopkins C, Slack R, Lund V et al (2009) Long-term outcomes from the English national comparative audit of surgery for nasal polyposis and chronic rhinosinusitis. Laryngoscope 119:2459–2465
Hosemann W (2001) Innere Nase und Nasennebenhöhlen. In: Strutz J, Mann W (Hrsg) Praxis der HNO-Heilkunde, Kopf- und Halschirurgie. Thieme, Stuttgart, S 342–390
Hosemann W (2003) Postoperative Rezidivprophylaxe bei chronischer Pansinusitis und Polyposis nasi. HNO 51:279–283
Hosemann W (2009) Stellungnahme der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie zur Ballon-Dilatation der Ostien bzw. der Drainagewege von Nasennebenhöhlen („Ballon-Sinuplasty, balloon catheter sinusotomy, balloon catheter sinus ostial dilation“). HNO-Informationen 34:48–49
Hosemann W, Fanghänel J (2005) Präparierkurs zur endoskopischen endonasalen Nasennebenhöhlenchirurgie. Endo-Press, Tuttlingen
Hosemann W, Schwab N, Praetner L et al (2003) Lebensqualität nach funktionell-endoskopischer Nasennebenhöhlen-Operation bei Polyposis nasi (Eine Langzeitstudie). Laryngorhinootologie 82:341–346
Hosemann W, Scotti O, Bentzien S (2003) Evaluation of telescopes and forceps for endoscopic transnasal surgery on the maxillary sinus. Am J Rhinol 17:311–316
Hosemann W, Weber R, Keerl R et al (2000) Minimally invasive endonasal sinus surgery – principles, techniques, results, complications, revision surgery. Thieme, Stuttgart
Hosemann W, Wigand ME, Gode U et al (1991) Normal wound healing of the paranasal sinuses: clinical and experimental investigations. Eur Arch Otorhinolaryngol 248:390–394
Huang BY, Lloyd KM, DelGaudio JM et al (2009) Failed endoscopic sinus surgery: spectrum of CT findings in the frontal recess. Radiographics 29:177–195
Hwang PH, Irwin SB, Griest SE et al (2003) Radiologic correlates of symptom-based diagnostic criteria for chronic rhinosinusitis. Otolaryngol Head Neck Surg 128:489–496
Iinuma T, Hirota Y, Kase Y (1994) Radio-opacity of the paranasal sinuses. Conventional views and CT. Rhinology 32:134–136
IMS (2002) Institut für medizinische Statistik GmbH. Frankfurt
Jankowski R, Bodino C (2003) Evolution of symptoms associated to nasal polyposis following oral steroid treatment and nasalization of the ethmoid–radical ethmoidectomy is functional surgery for NPS. Rhinology 41:211–219
Jankowski R, Pigret D, Decroocq F (1997) Comparison of functional results after ethmoidectomy and nasalization for diffuse and severe nasal polyposis. Acta Otolaryngol 117:601–608
Jankowski R, Pigret D, Decroocq F et al (2006) Comparison of radical (nasalisation) and functional ethmoidectomy in patients with severe sinonasal polyposis. A retrospective study. Rev Laryngol Otol Rhinol (Bord) 127:131–140
Joe SA, Thambi R, Huang J (2008) A systematic review of the use of intranasal steroids in the treatment of chronic rhinosinusitis. Otolaryngol Head Neck Surg 139:340–347
Jones NS (2002) CT of the paranasal sinuses: a review of the correlation with clinical, surgical and histopathological findings. Clin Otolaryngol Allied Sci 27:11–17
Jones NS, Walker JL, Bassi S et al (2002) The intracranial complications of rhinosinusitis: can they be prevented? Laryngoscope 112:59–63
Kaiser L, Lew D, Hirschel B et al (1996) Effects of antibiotic treatment in the subset of common-cold patients who have bacteria in nasopharyngeal secretions. Lancet 347:1507–1510
Kalish LH, Arendts G, Sacks R et al (2009) Topical steroids in chronic rhinosinusitis without polyps: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 141:674–683
Kaplan BA, Kountakis SE (2004) Role of nasal endoscopy in patients undergoing endoscopic sinus surgery. Am J Rhinol 18:161–164
Karageorgopoulos DE, Giannopoulou KP, Grammatikos AP et al (2008) Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials. CMAJ 178:845–854 (EL Ia)
Karlsson G, Rundcrantz H (1982) A randomized trial of intranasal beclomethasone dipropionate after polypectomy. Rhinology 20:144–148
Kassel JC, King D, Spurling GK (2010) Saline nasal irrigation for acute upper respiratory tract infections. Cochrane Database Syst Rev 3:CD006821
Keerl R, Stankiewicz J, Weber R et al (1999) Surgical experience and complications during endonasal sinus surgery. Laryngoscope 109:546–550
Keerl R, Weber R, Drees G et al (1996) Individuelle Lernkurven der endonasalen mikro-endoskopischen Pansinusoperation. Laryngorhinootologie 75:338–343
Kehrl W, Sonnemann U, Dethlefsen U (2004) Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. Laryngoscope 114:738–742
Keith P, Nieminen J, Hollingworth K et al (2000) Efficacy and tolerability of fluticasone propionate nasal drops 400 μg once daily compared with placebo for the treatment of bilateral polyposis in adults. Clin Exp Allergy 30:1460–1468
Kenny TJ, Duncavage J, Bracikowski J et al (2001) Prospective analysis of sinus symptoms and correlation with paranasal computed tomography scan. Otolaryngol Head Neck Surg 125:40–43
Kern RC, Conley DB, Walsh W et al (2008) Perspectives on the etiology of chronic rhinosinusitis: an immune barrier hypothesis. Am J Rhinol 22:549–559
Khalil HS, Nunez DA (2006) Functional endoscopic sinus surgery for chronic rhinosinusitis. Cochrane Database Syst Rev 3:CD004458
Kilty SJ, Desrosiers MY (2008) The role of bacterial biofilms and the pathophysiology of chronic rhinosinusitis. Curr Allergy Asthma Rep 8:227–233
Klimek L, Bachert C (2000) Aktuelle Aspekte der nasalen Glukokortikosteroidtherapie. HNO 48:544–555
Klimek L, Pfaar O (2009) Aspirin intolerance: does desensitization alter the course of the disease? Immunol Allergy Clin North Am 29:669–675
Klossek JM, Dubreuil L, Richet H et al (1998) Bacteriology of chronic purulent secretions in chronic rhinosinusitis. J Laryngol Otol 112:1162–1166
Klossek JM, Federspil P (2005) Update on treatment guidelines for acute bacterial sinusitis. Int J Clin Pract 59:230–238
Kosling S, Knipping S, Stoevesandt D (2007) Tumoren und tumorahnliche Erkrankungen. Radiologe 47:613–620
Kountakis S, Jacobs J, Gosepath J (2008) Revision Sinus Surgery. Springer, Heidelberg
Krouse JH, Brown RW, Fineman SM et al (2007) Asthma and the unified airway. Otolaryngol Head Neck Surg 136:75–106
Kuhnel T, Hosemann W, Wagner W et al (1996) Wie traumatisierend ist die mechanische Schleimhautpflege nach Eingriffen an den Nasennebenhohlen? Eine histologisch-immunhistochemische Untersuchung. Laryngorhinootologie 75:575–579
Lacroix JS, Ricchetti A, Lew D et al (2002) Symptoms and clinical and radiological signs predicting the presence of pathogenic bacteria in acute rhinosinusitis. Acta Otolaryngol 122:192–196
Lambrou P, Zervas E, Oikonomidou E et al (2007) Eosinophilic infiltration in the nasal mucosa of rhinitis patients: is it affected by the presence of asthma or the allergic status of the patients? Ann Allergy Asthma Immunol 98:567–572
Lane AP, Pine HS, Pillsbury HC 3rd (2001) Allergy testing and immunotherapy in an academic otolaryngology practice: a 20-year review. Otolaryngol Head Neck Surg 124:9–15
Lang S, Jager L, Grevers G (2002) Zur Aussagefähigkeit koronarer Sekundärrekonstruktionen computertomographischer Sequenzen der Nasennebenhöhlen. Laryngorhinootologie 81:418–421
Lange B, Bachert C (2003) Die topische intranasale Therapie der allergischen Rhintis. Eine Wirksamkeits- und Kostenanalyse. Allergologie 26:177–195
Lanza DC, Kennedy DW (1992) Current concepts in the surgical management of chronic and recurrent acute sinusitis. J Allergy Clin Immunol 90:505–510 (discussion 511)
Larsen PL, Tingsgaard PK, Harcourt J et al (1998) Nasal polyps and their relation to polyps/hypertrophic polypoid mucosa in the paranasal sinuses: a macro-, endo-, and microscopic study of autopsy materials. Am J Rhinol 12:45–51
Larsen PL, Tos M (1991) Origin of nasal polyps. Laryngoscope 101:305–312
Lee JY, Byun JY (2008) Relationship between the frequency of postoperative debridement and patient discomfort, healing period, surgical outcomes, and compliance after endoscopic sinus surgery. Laryngoscope 118:1868–1872
Lee JY, Lee SH, Hong HS et al (2008) Is the canine fossa puncture approach really necessary for the severely diseased maxillary sinus during endoscopic sinus surgery? Laryngoscope 118:1082–1087
Lee JY, Simon RA, Stevenson DD (2007) Selection of aspirin dosages for aspirin desensitization treatment in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 119:157–164
Legent F, Bordure P, Beauvillain C et al (1994) A double-blind comparison of ciprofloxacin and amoxycillin/clavulanic acid in the treatment of chronic sinusitis. Chemotherapy 40(Suppl 1):8–15
Leunig A (2007) Endoskopische Chirurgie der lateralen Nasenwand, der Nasennebenhöhlen und vorderen Schädelbasis. Grundlagen und klinische Beispiele. Endo-Press, Tuttlingen
Leunig A, Braunschweig F, Havel M et al (2009) Bronchospasmus nach ASS-Einnahme. Ist es eine Aspirinintoleranz? MMW Fortschr Med 151:44–45
Levine H, Clemente M (2004) Sinus surgery, endoscopic and microscopic approaches. Thieme, Stuttgart
Lewison E (1970) Comparison of the effectiveness of topical and oral nasal decongestants. Eye Ear Nose Throat Mon 49:16–18
Leynaert B, Neukirch F, Demoly P et al (2000) Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol 106:201–205
Liang X, Jacobs R, Hassan B et al (2009) A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT) Part I. On subjective image quality. Eur J Radiol 75:265–269
Liang X, Lambrichts I, Sun Y et al (2009) A comparative evaluation of Cone Beam Computed Tomography (CBCT) and Multi-Slice CT (MSCT). Part II: On 3D model accuracy. Eur J Radiol 75:270–274
Lildholdt T, Rundcrantz H, Bende M et al (1997) Glucocorticoid treatment for nasal polyps. The use of topical budesonide powder, intramuscular betamethasone, and surgical treatment. Arch Otolaryngol Head Neck Surg 123:595–600
Lildholdt T, Rundcrantz H, Lindqvist N (1995) Efficacy of topical corticosteroid powder for nasal polyps: a double-blind, placebo-controlled study of budesonide. Clin Otolaryngol Allied Sci 20:26–30
Lim M, Citardi MJ, Leong JL (2008) Topical antimicrobials in the management of chronic rhinosinusitis: a systematic review. Am J Rhinol 22:381–389
Lindbaek M, Hjortdahl P, Johnsen UL (1996) Use of symptoms, signs, and blood tests to diagnose acute sinus infections in primary care: comparison with computed tomography. Fam Med 28:183–188
Ling FT, Kountakis SE (2007) Important clinical symptoms in patients undergoing functional endoscopic sinus surgery for chronic rhinosinusitis. Laryngoscope 117:1090–1093
Low DE, Desrosiers M, McSherry J et al (1997) A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ 156(Suppl 6):1–14
Lund VJ (2001) Evidence-based surgery in chronic rhinosinusitis. Acta Otolaryngol 121:5–9
Lund VJ, Flood J, Sykes AP et al (1998) Effect of fluticasone in severe polyposis. Arch Otolaryngol Head Neck Surg 124:513–518
Lund VJ, Kennedy DW (1997) Staging for rhinosinusitis. Otolaryngol Head Neck Surg 117:35–40
Lundeberg T, Laurell G, Thomas M (1988) Effect of acupuncture on sinus pain and experimentally induced pain. Ear Nose Throat J 67:565–566, 571–572, 574–575
Macdonald KI, McNally JD, Massoud E (2009) The health and resource utilization of Canadians with chronic rhinosinusitis. Laryngoscope 119:184–189
Marple BF, Stankiewicz JA, Baroody FM et al (2009) Diagnosis and management of chronic rhinosinusitis in adults. Postgrad Med 121:121–139
Marshall I (2000) Zinc for the common cold. Cochrane Database Syst Rev:CD001364
Matsui T, Arai H, Nakajo M et al (2003) Role of chronic sinusitis in cognitive functioning in the elderly. J Am Geriatr Soc 51:1818–1819
McAlister WH, Lusk R, Muntz HR (1989) Comparison of plain radiographs and coronal CT scans in infants and children with recurrent sinusitis. AJR Am J Roentgenol 153:1259–1264
McCormick DP, John SD, Swischuk LE et al (1996) A double-blind, placebo-controlled trial of decongestant-antihistamine for the treatment of sinusitis in children. Clin Pediatr (Phila) 35:457–460
McMains KC (2008) Safety in endoscopic sinus surgery. Curr Opin Otolaryngol Head Neck Surg 16:247–251
Melchart D, Linde K, Fischer P et al (2000) Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev:CD000530
Melroy CT, Kuhn FA (2009) Safety of ethmoid sinus drug-eluting catheter insertion. Ann Otol Rhinol Laryngol 118:708–713
Meltzer EO, Charous BL, Busse WW et al (2000) Added relief in the treatment of acute recurrent sinusitis with adjunctive mometasone furoate nasal spray. The Nasonex Sinusitis Group. J Allergy Clin Immunol 106:630–637
Meltzer EO, Hamilos DL, Hadley JA et al (2004) Rhinosinusitis: Establishing definitions for clinical research and patient care. Otolaryngol Head Neck Surg 131:1–62
Meltzer EO, Orgel HA, Backhaus JW et al (1993) Intranasal flunisolide spray as an adjunct to oral antibiotic therapy for sinusitis. J Allergy Clin Immunol 92:812–823 (EL Ib)
Milewski M, Mastalerz L, Nizankowska E et al (1998) Nasal provocation test with lysine-aspirin for diagnosis of aspirin-sensitive asthma. J Allergy Clin Immunol 101:581–586
Min YG, Jung HW, Kim HS et al (1996) Prevalence and risk factors of chronic sinusitis in Korea: results of a nationwide survey. Eur Arch Otorhinolaryngol 253:435–439
Mosges R, Spaeth J, Berger K et al (2002) Topical treatment of rhinosinusitis with fusafungine nasal spray. A double-blind, placebo-controlled, parallel-group study in 20 patients. Arzneimittelforschung 52:877–883
Muntz HR, Lusk RP (1991) Bacteriology of the ethmoid bullae in children with chronic sinusitis. Arch Otolaryngol Head Neck Surg 117:179–181
Murphy MP, Fishman P, Short SO et al (2002) Health care utilization and cost among adults with chronic rhinosinusitis enrolled in a health maintenance organization. Otolaryngol Head Neck Surg 127:367–376
Mygind N, Dahl R, Nielsen LP et al (1997) Effect of corticosteroids on nasal blockage in rhinitis measured by objective methods. Allergy 52:39–44
Namyslowski G, Misiolek M, Czecior E et al (2002) Comparison of the efficacy and tolerability of amoxycillin/clavulanic acid 875 mg b.i.d. with cefuroxime 500 mg b.i.d. in the treatment of chronic and acute exacerbation of chronic sinusitis in adults. J Chemother 14:508–517
Nayak AS, Settipane GA, Pedinoff A et al (2002) Effective dose range of mometasone furoate nasal spray in the treatment of acute rhinosinusitis. Ann Allergy Asthma Immunol 89:271–278
Neubauer N, März R (1994) Placebo-controlled, randomized double-blind clinical trial with Sinupret sugar-coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1:177–181
Nilssen EL, Wardrop P, El-Hakim H et al (2002) A randomized control trial of post-operative care following endoscopic sinus surgery: debridement versus no debridement. J Laryngol Otol 116:108–111
Nizankowska-Mogilnicka E, Bochenek G, Mastalerz L et al (2007) EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity. Allergy 62:1111–1118
Nizankowska E, Duplaga M, Bochenek G et al (1998) Clinical course of aspirin induced asthma: results of AIANE. In: Szczecklik A, Gryglewski RJ (eds) Eicosanoids, aspirin and asthma. Marcel Dekker, New York, p 451–471
O’Hara J, Jones NS (2006) „Post-nasal drip syndrome“: most patients with purulent nasal secretions do not complain of chronic cough. Rhinology 44:270–273
Ophir D, Elad Y (1987) Effects of steam inhalation on nasal patency and nasal symptoms in patients with the common cold. Am J Otolaryngol 8:149–153
Orobello PW Jr, Park RI, Belcher LJ et al (1991) Microbiology of chronic sinusitis in children. Arch Otolaryngol Head Neck Surg 117:980–983
Padberg J, Bauer T (2006) Erkältungskrankheiten. Dtsch Med Wochenschr 131:2341–2349 (quiz 2351–2342)
Pang YT, Willatt DJ (1996) Do antral washouts have a place in the current management of chronic sinusitis? J Laryngol Otol 110:926–928
Pant H, Ferguson BJ, Macardle PJ (2009) The role of allergy in rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 17:232–238
Parikh AA, Scadding GK (2005) Intranasal lysine-aspirin in aspirin-sensitive nasal polyposis: a controlled trial. Laryngoscope 115:1385–1390
Patou J, Gevaert P, Van Zele T et al (2008) Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J Allergy Clin Immunol 121:110–115
Patriarca G, Bellioni P, Nucera E et al (1991) Intranasal treatment with lysine acetylsalicylate in patients with nasal polyposis. Ann Allergy 67:588–592
Pawankar R, Zernotti ME (2009) Rhinosinusitis in children and asthma severity. Curr Opin Allergy Clin Immunol 9:151–153
Pearlman AN, Conley DB (2008) Review of current guidelines related to the diagnosis and treatment of rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 16:226–230
Pelikan Z (2009) Diagnostic value of nasal allergen challenge combined with radiography and ultrasonography in chronic maxillary sinus disease. Arch Otolaryngol Head Neck Surg 135:1246–1255
Penttila M, Poulsen P, Hollingworth K et al (2000) Dose-related efficacy and tolerability of fluticasone propionate nasal drops 400 μg once daily and twice daily in the treatment of bilateral nasal polyposis: a placebo-controlled randomized study in adult patients. Clin Exp Allergy 30:94–102
Pfaar O, Klimek L (2006) Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements. Curr Opin Allergy Clin Immunol 6:161–166
Pfaar O, Klimek L (2006) Eicosanoids, aspirin-intolerance and the upper airways – current standards and recent improvements of the desensitization therapy. J Physiol Pharmacol 57(Suppl 12):5–13
Pfaar O, Spielhaupter M, Wrede H et al (2006) Adaptive Desaktivierung bei ASS-intoleranten Patienten mit Polyposis nasi et sinuum. Allergologie 29:322–332
Piccirillo JF, Mager DE, Frisse ME et al (2001) Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. JAMA 286:1849–1856
Pleis JR, Coles R (2002) Summary health statistics for U.S. adults: National Health Interview Survey, 1998. Vital Health Stat 10:1–113
Poetker DM, Litvack JR, Mace JC et al (2008) Recurrent acute rhinosinusitis: presentation and outcomes of sinus surgery. Am J Rhinol 22:329–333
Ponikau JU, Sherris DA, Kern EB et al (1999) The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc 74:877–884
Ponikau JU, Sherris DA, Weaver A et al (2005) Treatment of chronic rhinosinusitis with intranasal amphotericin B: a randomized, placebo-controlled, double-blind pilot trial. J Allergy Clin Immunol 115:125–131
Prince AA, Steiger JD, Khalid AN et al (2008) Prevalence of biofilm-forming bacteria in chronic rhinosinusitis. Am J Rhinol 22:239–245
Rabago D, Zgierska A, Mundt M et al (2002) Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: a randomized controlled trial. J Fam Pract 51:1049–1055
Ragab SM, Lund VJ, Scadding G (2004) Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial. Laryngoscope 114:923–930
Ramadan HH (1995) What is the bacteriology of chronic sinusitis in adults? Am J Otolaryngol 16:303–306
Ramadan HH, McLaughlin K, Josephson G et al (2010) Balloon catheter sinuplasty in young children. Am J Rhinol Allergy 24:e54–e56
Rasp G (2010) Is there a role for leukotriene antagonists in the prevention of recurrent nasal polyps? Curr Opin Allergy Clin Immunol 10:200–205
Rasp G, Kramer MF, Ostertag P et al (2000) Ein neues System zur Einteilung der Siebbeinpolyposis. Einfluss einer kombinierten lokalen und systemischen Steroidtherapie. Laryngorhinootologie 79:266–272
Rawlings BA, Han JK (2010) Level of complete dissection of the ethmoid sinuses with a computed tomographic image guidance system. Ann Otol Rhinol Laryngol 119:17–21
Ray NF, Baraniuk JN, Thamer M et al (1999) Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders. J Allergy Clin Immunol 103:408–414
Reardon EJ (2002) Navigational risks associated with sinus surgery and the clinical effects of implementing a navigational system for sinus surgery. Laryngoscope 112:1–19
Rice D, Schaefer S (2004) Endoscopic paranasal sinus surgery. Lippincott Williams & Wilkins, Philadelphia
Rohr AS, Spector SL, Siegel SC et al (1986) Correlation between A-mode ultrasound and radiography in the diagnosis of maxillary sinusitis. J Allergy Clin Immunol 78:58–61
Rosbe KW, Jones KR (1998) Usefulness of patient symptoms and nasal endoscopy in the diagnosis of chronic sinusitis. Am J Rhinol 12:167–171
Roseler S, Holtappels G, Wagenmann M et al (1995) Elevated levels of interleukins IL-1 beta, IL-6 and IL-8 in naturally acquired viral rhinitis. Eur Arch Otorhinolaryngol 252(Suppl 1):61–63
Rosenfeld RM (2007) Clinical practice guideline on adult sinusitis. Otolaryngol Head Neck Surg 137:365–377
Rosenfeld RM, Andes D, Bhattacharyya N et al (2007) Clinical practice guideline: adult sinusitis. Otolaryngol Head Neck Surg 137:1–31
Rosenfeld RM, Singer M, Jones S (2007) Systematic review of antimicrobial therapy in patients with acute rhinosinusitis. Otolaryngol Head Neck Surg 137:32–45
Rossberg E, Larsson PG, Birkeflet O et al (2005) Comparison of traditional Chinese acupuncture, minimal acupuncture at non-acupoints and conventional treatment for chronic sinusitis. Complement Ther Med 13:4–10
Rudack C, Hauser U, Wagenmann M et al (1998) Zytokinmuster bei verschiedenen Formen der Nasennebenhöhlenentzündungen. Laryngorhinootologie 77:34–37
Rudack C, Stoll W, Bachert C (1998) Cytokines in nasal polyposis, acute and chronic sinusitis. Am J Rhinol 12:383–388
Ruhno J, Andersson B, Denburg J et al (1990) A double-blind comparison of intranasal budesonide with placebo for nasal polyposis. J Allergy Clin Immunol 86:946–953
Samter M, Beers RF Jr (1968) Intolerance to aspirin. Clinical studies and consideration of its pathogenesis. Ann Intern Med 68:975–983
Sauer M, Lemmens W, Vauterin T et al (2007) Comparing the microdebrider and standard instruments in endoscopic sinus surgery: a double-blind randomised study. B-ENT 3:1–7
Savolainen S, Jousimies-Somer H, Kleemola M et al (1989) Serological evidence of viral or Mycoplasma pneumoniae infection in acute maxillary sinusitis. Eur J Clin Microbiol Infect Dis 8:131–135
Savvateeva DM, Guldner C, Murthum T et al (2010) Digital volume tomography (DVT) measurements of the olfactory cleft and olfactory fossa. Acta Otolaryngol 130:398–404
Schmitz-Schumann M, Schaub E, Virchow C (1982) Inhalative Provokation mit Lysin-Azetylsalizylsäure bei Analgetika-Asthma-Syndrom. Prax Klin Pneumol 36:17–21
Seiberling K, Jardeleza C, Wormald PJ (2009) Minitrephination of the frontal sinus: indications and uses in today’s era of sinus surgery. Am J Rhinol Allergy 23:229–231
Seiberling K, Ooi E, MiinYip J et al (2009) Canine fossa trephine for the severely diseased maxillary sinus. Am J Rhinol Allergy 23:615–618
Selivanova O, Kuehnemund M, Mann WJ et al (2003) Comparison of conventional instruments and mechanical debriders for surgery of patients with chronic sinusitis. Am J Rhinol 17:197–202
Seltzer AP (1967) Adjunctive use of bromelains in sinusitis: a controlled study. Eye Ear Nose Throat Mon 46:1281–1288
Senior BA, Kennedy DW, Tanabodee J et al (1998) Long-term results of functional endoscopic sinus surgery. Laryngoscope 108:151–157
Setliff RC 3rd (1996) Minimally invasive sinus surgery: the rationale and the technique. Otolaryngol Clin North Am 29:115–124
Settipane GA (1996) Nasal polyps and immunoglobulin E (IgE). Allergy Asthma Proc 17:269–273
Shapiro GG, Furukawa CT, Pierson WE et al (1986) Blinded comparison of maxillary sinus radiography and ultrasound for diagnosis of sinusitis. J Allergy Clin Immunol 77:59–64
Shashy RG, Moore EJ, Weaver A (2004) Prevalence of the chronic sinusitis diagnosis in Olmsted County, Minnesota. Arch Otolaryngol Head Neck Surg 130:320–323
Simasek M, Blandino DA (2007) Treatment of the common cold. Am Fam Physician 75:515–520
Simmen D, Jones N (2005) Chirurgie der Nasennebenhöhlen und der vorderen Schädelbasis. Thieme, Stuttgart
Sindwani R (2008) Image-guided surgery of the paranasal sinuses and skull base. Mo Med 105:257–261
Smith TL, Batra PS, Seiden AM et al (2005) Evidence supporting endoscopic sinus surgery in the management of adult chronic rhinosinusitis: a systematic review. Am J Rhinol 19:537–543
Smith TL, Stewart MG, Orlandi RR et al (2007) Indications for image-guided sinus surgery: the current evidence. Am J Rhinol 21:80–83
Smith WM, Davidson TM, Murphy C (2009) Regional variations in chronic rhinosinusitis, 2003–2006. Otolaryngol Head Neck Surg 141:347–352
Soler ZM, Mace J, Smith TL (2008) Symptom-based presentation of chronic rhinosinusitis and symptom-specific outcomes after endoscopic sinus surgery. Am J Rhinol 22:297–301
Soyka MB, Holzmann D (2005) Correlation of complications during endoscopic sinus surgery with surgeon skill level and extent of surgery. Am J Rhinol 19:274–281
Spector SL, Bernstein IL, Li JT et al (1998) Parameters for the diagnosis and management of sinusitis. J Allergy Clin Immunol 102:107–144
Stamm A, Draf W (2000) Micro-endoscopic surgery of the paranasal sinuses and the skull base. Springer, Berlin
Stammberger H (1991) Functional endoscopic sinus surgery. The Messerklinger Technique. BC Decker, Philadelphia
Stankiewicz J (1997) Chronic sinusitis. In: Johnson J, Yu V (eds) Infectious Deseases and Antimicrobial Therapy of the Ears, Nose and Throat. W.B. Saunders Company, Philadelphia, p 350–360
Stankiewicz JA (1989) Complications in endoscopic intranasal ethmoidectomy: an update. Laryngoscope 99:686–690
Stankiewicz JA, Chow JM (2002) A diagnostic dilemma for chronic rhinosinusitis: definition accuracy and validity. Am J Rhinol 16:199–202
Stevenson DD (2009) Aspirin sensitivity and desensitization for asthma and sinusitis. Curr Allergy Asthma Rep 9:155–163
Stevenson DD, Hankammer MA, Mathison DA et al (1996) Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. J Allergy Clin Immunol 98:751–758
Stevenson DD, Pleskow WW, Simon RA et al (1984) Aspirin-sensitive rhinosinusitis asthma: a double-blind crossover study of treatment with aspirin. J Allergy Clin Immunol 73:500–507
Stevenson DD, Simon RA, Mathison DA (1980) Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. J Allergy Clin Immunol 66:82–88
Strauss G (2009) Computerassistierte Chirurgie an der Rhinobasis. HNO 57:990–997
Strauss G, Hofer M, Korb W et al (2006) Genauigkeit und Präzision in der Bewertung von chirurgischen Navigations- und Assistenzsystemen. Eine Begriffsbestimmung. HNO 54:78–84
Strauss G, Limpert E, Strauss M et al (2009) Untersuchungen zur Effizienz eines Navigationssystems fur die HNO-Chirurgie: Auswertungen von 300 Patienten. Laryngorhinootologie 88:776–781
Stuck BA, Bachert C, Federspil P et al (2007) Leitlinie „Rhinosinusitis“ der Deutschen Gesellschaft fur Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. HNO 55:758–760, 762–764, 766–777
Sweet JM, Stevenson DD, Simon RA et al (1990) Long-term effects of aspirin desensitization – treatment for aspirin-sensitive rhinosinusitis-asthma. J Allergy Clin Immunol 85:59–65
Szczeklik A, Nizankowska E (2000) Clinical features and diagnosis of aspirin induced asthma. Thorax 55(Suppl 2):42–44
Szczeklik A, Nizankowska E, Duplaga M (2000) Natural history of aspirin-induced asthma. AIANE Investigators. European Network on Aspirin-Induced Asthma. Eur Respir J 16:432–436
Szczeklik A, Sanak M, Nizankowska-Mogilnicka E et al (2004) Aspirin intolerance and the cyclooxygenase-leukotriene pathways. Curr Opin Pulm Med 10:51–56
Szczeklik A, Stevenson DD (2003) Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J Allergy Clin Immunol 111:913–921 (quiz 922)
Tabaee A, Hsu AK, Shrime MG et al (2006) Quality of life and complications following image-guided endoscopic sinus surgery. Otolaryngol Head Neck Surg 135:76–80
Taccariello M, Parikh A, Darby Y et al (1999) Nasal douching as a valuable adjunct in the management of chronic rhinosinusitis. Rhinology 37:29–32
Takeuchi H, Jawad MS, Eccles R (1999) The effects of nasal massage of the „yingxiang“ acupuncture point on nasal airway resistance and sensation of nasal airflow in patients with nasal congestion associated with acute upper respiratory tract infection. Am J Rhinol 13:77–79
Talbot AR, Herr TM, Parsons DS (1997) Mucociliary clearance and buffered hypertonic saline solution. Laryngoscope 107:500–503
Tan BK, Schleimer RP, Kern RC (2010) Perspectives on the etiology of chronic rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 18:21–26
Tantilipikorn P, Fritz M, Tanabodee J et al (2002) A comparison of endoscopic culture techniques for chronic rhinosinusitis. Am J Rhinol 16:255–260
Taub SJ (1967) The use of bromelains in sinusitis: a double-blind clinical evaluation. Eye Ear Nose Throat Mon 46:361–362 (passim)
Brinke A ten, Grootendorst DC, Schmidt JT et al (2002) Chronic sinusitis in severe asthma is related to sputum eosinophilia. J Allergy Clin Immunol 109:621–626
Tesche S, Metternich F, Sonnemann U et al (2008) The value of herbal medicines in the treatment of acute non-purulent rhinosinusitis. Results of a double-blind, randomised, controlled trial. Eur Arch Otorhinolaryngol 265:1355–1359
Teul I, Zbislawski W, Baran S et al (2007) Quality of life of patients with diseases of sinuses. J Physiol Pharmacol 58(Suppl 5):691–697
Tolsdorff B, Pommert A, Hohne KH et al (2010) Virtual reality: a new paranasal sinus surgery simulator. Laryngoscope 120:420–426
Tomooka LT, Murphy C, Davidson TM (2000) Clinical study and literature review of nasal irrigation. Laryngoscope 110:1189–1193
Tos M, Svendstrup F, Arndal H et al (1998) Efficacy of an aqueous and a powder formulation of nasal budesonide compared in patients with nasal polyps. Am J Rhinol 12:183–189
Tschopp KP, Thomaser EG (2008) Outcome of functional endonasal sinus surgery with and without CT-navigation. Rhinology 46:116–120
Turner BW, Cail WS, Hendley JO et al (1992) Physiologic abnormalities in the paranasal sinuses during experimental rhinovirus colds. J Allergy Clin Immunol 90:474–478
Tyrrell D, Barrow I, Arthur J (1989) Local hyperthermia benefits natural and experimental common colds. BMJ 298:1280–1283
Vairaktaris E, Moschos MM, Vassiliou S et al (2009) Orbital cellulitis, orbital subperiosteal and intraorbital abscess: report of three cases and review of the literature. J Craniomaxillofac Surg 37:132–136
Van Bruaene N, Derycke L, Perez-Novo CA et al (2009) TGF-beta signaling and collagen deposition in chronic rhinosinusitis. J Allergy Clin Immunol 124:253–259, e251–e252
Van Bruaene N, Perez-Novo CA, Basinski TM et al (2008) T-cell regulation in chronic paranasal sinus disease. J Allergy Clin Immunol 121:1435–1441, e1431–e1433
Buchem L van, Peeters M, Beaumont J et al (1995) Acute maxillary sinusitis in general practice: the relation between clinical picture and objective findings. Eur J Gen Pract 1:155–160
Camp C van, Clement PA (1994) Results of oral steroid treatment in nasal polyposis. Rhinology 32:5–9
Van Zele T, Claeys S, Gevaert P et al (2006) Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 61:1280–1289
Van Zele T, Gevaert P, Holtappels G et al (2007) Local immunoglobulin production in nasal polyposis is modulated by superantigens. Clin Exp Allergy 37:1840–1847
Van Zele T, Gevaert P, Watelet JB et al (2004) Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis. J Allergy Clin Immunol 114:981–983
Van Zele T, Vaneechoutte M, Holtappels G et al (2008) Detection of enterotoxin DNA in Staphylococcus aureus strains obtained from the middle meatus in controls and nasal polyp patients. Am J Rhinol 22:223–227
Varonen H, Makela M, Savolainen S et al (2000) Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. J Clin Epidemiol 53:940–948
Vaughan WC (2008) Review of balloon sinuplasty. Curr Opin Otolaryngol Head Neck Surg 16:2–9
Vauterin T, Poorten VV, Jorissen M (2000) Cutting forceps in functional endoscopic sinus surgery. Acta Otorhinolaryngol Belg 54:29–37
Vauterin T, Vander Poorten V, Jorissen M (2006) Long term effects of cutting forceps in endoscopic sinus surgery. Rhinology 44:123–127
Vickers AJ, Rees RW, Zollman CE et al (2004) Acupuncture for chronic headache in primary care: large, pragmatic, randomised trial. BMJ 328:744
Virolainen E, Puhakka H (1980) The effect of intranasal beclomethasone dipropionate on the recurrence of nasal polyps after ethmoidectomy. Rhinology 18:9–18
Wagenmann M (2004) Die allergische Pilzsinusitis. In: Schultze-Werninghaus G, Fuchs T, Bachert C, Wahn U (eds) Manuale allergologicum. Dustri, Oberhaching
Wallwork B, Coman W, Mackay-Sim A et al (2006) A double-blind, randomized, placebo-controlled trial of macrolide in the treatment of chronic rhinosinusitis. Laryngoscope 116:189–193
Weber R (2006) Persistierende chronische Sinusitis nach Nasennebenhöhlenoperation. Laryngorhinootologie 85:667–685
Weber R, Draf W, Keerl R et al (1995) Aspekte zur Stirnhöhlenchirurgie. Teil III: Indikation und Ergebnisse der osteoplastischen Stirnhöhlenoperation. HNO 43:414–420
Weber R, Draf W, Kratzsch B et al (2001) Modern concepts of frontal sinus surgery. Laryngoscope 111:137–146
Weber R, Hosemann W (2010) Nachbehandlung nach endonasaler Nasennebenhöhlenoperation. In: Weber R, Hosemann W (Hrsg) Nachbehandlung nach HNO-Operationen. Giebel, Eiterfeld
Weber R, Keerl R, Hosemann W et al (1998) Komplikationen mit bleibenden Schäden bei endonasalen Nasennebenhöhlenoperationen – häufiger bei erfahrenen Operateuren? Laryngorhinootologie 77:398–401
Weber R, Keerl R, Huppmann A et al (1996) Der Einfluss der Nachbehandlung auf die Wundheilung nach endonasaler Nasennebenhöhlenoperation. Laryngorhinootologie 75:208–214
Weiss RL, Church CA, Kuhn FA et al (2008) Long-term outcome analysis of balloon catheter sinusotomy: two-year follow-up. Otolaryngol Head Neck Surg 139:38–46
Welch KC, Stankiewicz JA (2009) A contemporary review of endoscopic sinus surgery: techniques, tools, and outcomes. Laryngoscope 119:2258–2268
Weschta M, Rimek D, Formanek M et al (2004) Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: a randomized, double-blind clinical trial. J Allergy Clin Immunol 113:1122–1128
West B, Jones NS (2001) Endoscopy-negative, computed tomography-negative facial pain in a nasal clinic. Laryngoscope 111:581–586
Wiegand M (2008) Endoscopic surgery of the paranasal sinuses and anterior skull base. Thieme, Stuttgart
Wiklund L, Stierna P, Berglund R et al (1994) The efficacy of oxymetazoline administered with a nasal bellows container and combined with oral phenoxymethyl-penicillin in the treatment of acute maxillary sinusitis. Acta Otolaryngol Suppl 515:57–64
Williams JW Jr, Aguilar C, Cornell J et al (2003) Antibiotics for acute maxillary sinusitis. Cochrane Database Syst Rev:CD000243
Williams JW Jr, Simel DL (1993) Does this patient have sinusitis? Diagnosing acute sinusitis by history and physical examination. JAMA 270:1242–1246
Williams JW Jr, Simel DL, Roberts L et al (1992) Clinical evaluation for sinusitis. Making the diagnosis by history and physical examination. Ann Intern Med 117:705–710
Williams JWJ, Aguilar C, Makela M et al (2000) Review: Penicillin V or amoxicillin is better than placebo and equal to non-penicillins for acute maxillary sinusitis. Evid Based Med 5:43 (EL Ia)
Williamson IG, Rumsby K, Benge S et al (2007) Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. JAMA 298:2487–2496
Winther B, Gwaltney JM, Hendley JO (1990) Respiratory virus infection of monolayer cultures of human nasal epithelial cells. Am Rev Respir Dis 141:839–845
Wittkopf ML, Becker SS, Duncavage JA et al (2009) Balloon sinuplasty for the surgical management of immunocompromised and critically ill patients with acute rhinosinusitis. Otolaryngol Head Neck Surg 140:596–598
Wormald P (2007) Endoscopic Sinus Surgery: Anatomy, Three-dimensional Reconstruction, and Surgical Technique. Thieme, Stuttgart
Wynn R, Har-El G (2004) Recurrence rates after endoscopic sinus surgery for massive sinus polyposis. Laryngoscope 114:811–813
Young J, De Sutter A, Merenstein D et al (2008) Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data. Lancet 371:908–914
Zalmanovici A, Yaphe J (2009) Intranasal steroids for acute sinusitis. Cochrane Database Syst Rev:CD005149
Zeiss CR, Lockey RF (1976) Refractory period to aspirin in a patient with aspirin-induced asthma. J Allergy Clin Immunol 57:440–448
Zhang N, Gevaert P, Zele T van et al (2005) An update on the impact of Staphylococcus aureus enterotoxins in chronic sinusitis with nasal polyposis. Rhinology 43:162–168
Zhang N, Van Zele T, Perez-Novo C et al (2008) Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J Allergy Clin Immunol 122:961–968
Zinreich SJ, Kennedy DW, Rosenbaum AE et al (1987) Paranasal sinuses: CT imaging requirements for endoscopic surgery. Radiology 163:769–775
Zoumalan RA, Lebowitz RA, Wang E et al (2009) Flat panel cone beam computed tomography of the sinuses. Otolaryngol Head Neck Surg 140:841–844
Danksagung
Redaktionelle Unterstützung: cand. med. Franziska Lenz, Mannheim
Interessenkonflikt
Siehe Anhang, Kap. „Finanzierung und Interessenkonflikte“.
Author information
Authors and Affiliations
Corresponding author
Anhang
Anhang
Herausgeber: Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V.
Stand: 01.03.2011
Revision: 3 Jahre nach Veröffentlichung, bei Erscheinen substanziell neuer Evidenzen ggf. früher
Verantwortlich für die Überarbeitung: Prof. Dr. med. Boris A. Stuck
Termine und Teilnehmer der nominalen Gruppenprozesse und des Delphi-Verfahrens
Der nominale Gruppenprozess zur Aktualisierung der Leitlinie fand am 24. und 25. August 2010 unter der Leitung von Herrn Priv.-Doz. Dr. med. H. Sitter (Institut für Chirurgische Forschung, Marburg) unter Beteiligung verschiedener Fachvertreter in Mannheim statt. Die Teilnehmer waren im Einzelnen: Frau Prof. Dr. med. S. Kösling (Vertreterin der Arbeitsgemeinschaft Kopf-Hals-Diagnostik der Deutschen Röntgengesellschaft), Herr Dr. med. G. Gronke (Leiter Ressort Leitlinien des Deutschen Berufsverbandes der Hals-Nasen-Ohren-Ärzte e. V.), Prof. Dr. med. C. Bachert (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Teilnahme nur am 25.08.2010), Prof. Dr. med. P. Federspil (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. W. Hosemann (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. K. Hörmann (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. L. Klimek (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Teilnahme nur am 25.08.2010), Prof. Dr. med. Dipl. Ing. R. Mösges (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Priv.-Doz. Dr. med. O. Pfaar (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. B.A. Stuck (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde) und Prof. Dr. med. R. Weber (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Teilnahme nur am 24.08.2010).
Die Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM) hat ebenfalls an der Überarbeitung mitgewirkt und Herr Prof. Dr. med. A. Podbielski als Vertreter benannt. Dieser hat umfangreiche Kommentare zur Leitlinie erstellt, jedoch nicht am nominalen Gruppenprozess teilgenommen. Die DGHM hat Prof. Dr. med. B.A. Stuck autorisiert, die Kommentare im Rahmen des nominalen Gruppenprozesses einzubringen.
Des Weiteren wurde die Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin (DGAM) aufgefordert, an der Aktualisierung der Leitlinie mitzuwirken. Dies wurde jedoch von Seiten der DGAM abgelehnt. Ferner wurde die Bundesarbeitsgemeinschaft Selbsthilfe mehrfach schriftlich wie fernmündlich gebeten, an der Leitlinie mitzuwirken. Die Anfragen wurden jedoch nicht beantwortet.
Die Teilnehmer am nominalen Gruppenprozess erhielten am 06.07.2010 eine Tischvorlage der Leitlinie. Auf der Basis dieser Tischvorlage wurde die Leitlinie entsprechend der formalen Vorgaben für nominale Gruppenprozesse diskutiert und in strittigen Fragen per Abstimmung ein Konsens erzielt. Im Rahmen der Abstimmung genügte die einfache Mehrheit.
Die im Rahmen des nominalen Gruppenprozesses überarbeitete Fassung wurde dann in einem Delphi-Verfahren abschließend konsertiert. Am Delphi-Verfahren nahmen die Autoren der Leitlinie und die Fachvertreter der Deutschen Röntgengesellschaft, der Deutschen Gesellschaft für Hygiene und Mikrobiologie und des Berufsverbandes für Hals-Nasen-Ohren-Ärzte teil.
Der zur Erstellung der Empfehlungen der Leitlinie notwendige Konsensprozess wurde durch die Kombination zweier formalisierter Konsensverfahren erzielt. Die hierzu eingesetzten Verfahren sind der nominale Gruppenprozess und die Delphi-Technik. Beim nominalen Gruppenprozess treffen sich die Beteiligten unter Leitung eines neutralen Moderators zu streng strukturierten Sitzungen, deren Ablauf in folgende Schritte gegliedert ist:
-
1.
Präsentation der zu konsentierenden Aussagen.
-
2.
Jeder Teilnehmer verfasst Änderungsvorschläge und Anmerkungen zu den vorgeschlagenen Aussagen und Algorithmen.
-
3.
Diese Kommentare werden der Reihe nach von einem unabhängigen und nicht stimmberechtigten Moderator abgefragt und gesammelt. Ähnliche Kommentare werden zusammengefasst.
-
4.
Über jeden Vorschlag wird abgestimmt, ob darüber diskutiert werden soll.
-
5.
Daraus ergibt sich eine Rangfolge der Vorschläge für die Diskussion.
-
6.
Nun findet die Diskussion gemäß der Rangfolge statt.
-
7.
Die Mehrheitsentscheidung zu jedem Punkt wird protokolliert und die Leitlinie wird gemäß dieser Beschlüsse bis zum nächsten Treffen überarbeitet.
-
8.
Beim nächsten Treffen durchläuft man wieder die obigen Schritte 1 bis 6 für die überarbeitete Version.
Dieses Verfahren wird bis zur Erzielung eines Konsenses fortgesetzt. Für Fragen, die bei der obigen Priorisierung eine untergeordnete Rolle spielten, wurde die Delphi-Technik benutzt. Bei einem Delphi-Prozess verläuft die Konsensfindung analog zu den oben beschriebenen Schritten, jedoch treffen sich die Teilnehmer nicht, sondern kommunizieren nur auf schriftlichem Wege.
Für die Leitlinie wurde abschließend eine Kurzfassung erstellt, die sich vornehmlich aus grundsätzlichen methodischen und nosologischen Ausführungen sowie den Empfehlungen zur Diagnostik und Therapie zusammensetzt. Diese Kurzfassung wurde ebenfalls im Rahmen des Delphi-Prozesses abgestimmt.
Finanzierung und Interessenkonflikte
Die Leitlinie wurde ohne externe Finanzierung und ausschließlich mit den Finanzmitteln der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie entwickelt. Alle Autoren haben ihre Interessenkonflikte offengelegt, dabei waren auch alle Beziehungen zu Einrichtungen der pharmazeutischen Industrie und zu Medizinprodukteherstellern anzugeben. Die Angaben wurden durch das Koordinatorenteam bewertet, dabei wurden keine Interessenkonflikte festgestellt, die die fachliche Unabhängigkeit der Autoren im Hinblick auf die Erstellung der Leitlinie beeinträchtigen könnten.
Gültigkeitsdauer und Aktualisierung
Diese Leitlinie ist gültig bis 01.03.2014, spätestens zu diesem Zeitpunkt erfolgt eine inhaltliche Überprüfung und ggf. eine Aktualisierung. Werden dem Leitlinienkoordinator zwischenzeitlich Erkenntnisse bekannt, die eine Überarbeitung der Leitlinie erfordern, so erfolgt die Aktualisierung bereits früher.
Verabschiedung der Leitlinie
Die vorliegende Fassung der Leitlinie wurde im April 2011vom Präsidium der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie beraten und angenommen.
Rights and permissions
About this article
Cite this article
Stuck, B., Bachert, C., Federspil, P. et al. Leitlinie „Rhinosinusitis“ – Langfassung. HNO 60, 141–162 (2012). https://doi.org/10.1007/s00106-011-2396-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00106-011-2396-7