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Granularzelltumor des Larynx

Granular cell tumor of the larynx: A case report

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Zusammenfassung

Granularzelltumoren (GZT) sind subkutan oder submukös gelegene, gutartige Tumoren neurogenen Ursprungs. Sie treten häufig im Kopf-Hals-Bereich auf, insbesondere in der Zunge. Bisher wurden etwa 200 laryngeale GZT beschrieben. Meist sind dabei die Stimmlippen und die posteriore Glottis betroffen. Eine Unterscheidung von einer chronischen Entzündung oder einem Malignom ist nur mittels Biopsie möglich. Als Therapie der Wahl wird die vollständige Exzision empfohlen, wobei Tumorausdehnung und zu erwartende Morbidität die Radikalität des Vorgehens bestimmen. Bei vollständiger Entfernung sind Rezidive selten.

Abstract

Granular cell tumors are benign subcutaneous or submucosal lesions of neurogenic origin. They are quite commonly found in the head and neck region, particularly in the tongue. However, only about 200 cases of laryngeal granular cell tumors have been reported so far. Most laryngeal granular cell tumors are located in the posterior part of the vocal fold and in the posterior commissure. Differentiation from inflammatory as well as from malignant lesions is possible only by biopsy. The treatment of choice is complete excision. However, tumor extension and expected morbidity of the surgery will inevitably influence the extent of the resection. Recurrences after complete excision are rare.

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Authors and Affiliations

  1. Abteilung Phoniatrie, HNO-Klinik, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz

    C. Storck, J. Egli, C. Fischer & M. Wolfensberger

  2. Institut für Pathologie, Universitätsspital Basel, Basel, Schweiz

    S. Savic

Authors
  1. C. Storck
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  2. S. Savic
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  3. J. Egli
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  4. C. Fischer
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  5. M. Wolfensberger
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Correspondence to C. Storck.

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Storck, C., Savic, S., Egli, J. et al. Granularzelltumor des Larynx. HNO 56, 1229–1232 (2008). https://doi.org/10.1007/s00106-008-1675-4

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  • DOI: https://doi.org/10.1007/s00106-008-1675-4

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