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Tuberöse Hirnsklerose

Laserdermabrasio und Fibrinversiegelung von fazialen Angiofibromen

Laser skin resurfacing and fibrin sealing as successful treatment for facial angiofibromas in tuberous sclerosis

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Zusammenfassung

Die tuberöse Sklerose ist eine autosomal-dominant vererbte Phakomatose, die die klassische Trias viszerale Hamartome, Epilepsie und geistige Retardierung beinhaltet und sich im HNO-Gebiet mit ausgedehnten perinasalen Angiofibromen manifestiert. Letztere können ein mechanisches, blutendes und stigmatisierendes Atemhindernis bedeuten. Für die Therapieplanung muss die Entartungstendenz der Läsionen und die Patienten-Compliance berücksichtigt werden. Vorgestellt wird eine 34-jährige Patientin, die mit einer Kombination aus CO2-Laser-Behandlung und Fibrinversiegelung rasch und ästhetisch sehr ansprechend behandelt wurde.

Abstract

Tuberous sclerosis complex (TSC) is an autosomal-dominant phacomatosis that manifests with visceral harmatomas, epilepsy, and mental retardation. Paranasal angiofibromas may cause bleeding and difficulties in nasal breathing and can stigmatise the individual. When treating TSC patients, the otolaryngologist must take patient compliance and the tendency to develop malignancies into account. We report on a 34-year-old woman who was treated successfully by a combination of CO2 laser treatment and fibrin glue. The cosmetic results were excellent.

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Authors and Affiliations

  1. Universitätsklinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde/Chirurgie, Rheinische Friedrich-Wilhelms-Universität, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland

    A. Pantelis & F. Bootz

  2. Hals-Nasen-Ohren-Klinik und Poliklinik der Universität Regensburg, Regensburg, Deutschland

    T. Kühnel

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  1. A. Pantelis
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  2. F. Bootz
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  3. T. Kühnel
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Correspondence to A. Pantelis.

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Pantelis, A., Bootz, F. & Kühnel, T. Tuberöse Hirnsklerose. HNO 55, 1009–1011 (2007). https://doi.org/10.1007/s00106-007-1618-5

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  • DOI: https://doi.org/10.1007/s00106-007-1618-5

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