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Leitlinie „Rhinosinusitis“ der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie

Rhinosinusitis Guidelines of the German Society for Otorhinolaryngology, Head and Neck Surgery

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Literatur

  1. Abuhammour WM, Abdel-Haq NM, Asmar BI, Dajani AS (1999) Moraxella catarrhalis bacteremia: a 10-year experience. South Med J 92: 1071–1074

    PubMed  CAS  Google Scholar 

  2. Ackerhans M, Jannert M, Tonnesson M (1994) Effects of a new administration form of oxymetazoline on maxillary ostial patency in healthy individuals and patients with acute rhinitis. Acta Otolaryngol Suppl 515: 49–52

    PubMed  CAS  Google Scholar 

  3. Adam P, Stiffman M, Blake RL Jr (1998) A clinical trial of hypertonic saline nasal spray in subjects with the common cold or rhinosinusitis. Arch Fam Med 7: 39–43

    PubMed  CAS  Google Scholar 

  4. American Thoracic Society Workshop (1999) Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options. Am J Respir Crit Care Med 160: 1778–1787

    Google Scholar 

  5. Anand VK (2004) Epidemiology and economic impact of rhinosinusitis. Ann Otol Rhinol Laryngol Suppl 193: 3–5

    PubMed  Google Scholar 

  6. AWMF (2001) Das Leitlinien-Manual von AWMF und ÄZQ. Z Arztl Fortbild Qualitatssich 95: 1–84

    Google Scholar 

  7. Bachert C (1998) Die Wirkung von Benzalkoniumchlorid auf das Flimmerepithel der Schleimhaut. HNO 46: 90–92

    PubMed  CAS  Google Scholar 

  8. Bachert C, Gevaert P, Holtappels G et al. (2001) Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 107: 607–614

    PubMed  CAS  Google Scholar 

  9. Bachert C, Wagenmann M, Hauser U, Rudack C (1997) IL-5 synthesis is upregulated in human nasal polyp tissue. J Allergy Clin Immunol 99: 837–842

    PubMed  CAS  Google Scholar 

  10. Bachert C, Wagenmann M, Rudack C et al. (1998) The role of cytokines in infectious sinusitis and nasal polyposis. Allergy 53: 2–13

    PubMed  CAS  Google Scholar 

  11. Bachmann G, Hommel G, Michel O (2000) Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease. Eur Arch Otorhinolaryngol 257: 537–541

    PubMed  CAS  Google Scholar 

  12. Badia L, Lund V (2001) Topical corticosteroids in nasal polyposis. Drugs 61: 573–578

    PubMed  CAS  Google Scholar 

  13. Bauchau V, Durham SR (2004) Prevalence and rate of diagnosis of allergic rhinitis in Europe. Eur Respir J 24: 758–764

    PubMed  CAS  Google Scholar 

  14. Behrbohm H, Kaschke O, Sydow K (1995) Der Einfluss des pflanzlichen Sekretolytikums Gelomyrtol forte auf die mukoziliare Clearance der Kieferhöhle. Laryngorhinootologie 74: 733–737

    PubMed  CAS  Google Scholar 

  15. Benninger MS, Sedory Holzer SE, Lau J (2000) Diagnosis and treatment of uncomplicated acute bacterial rhinosinusitis: summary of the Agency for Health Care Policy and Research evidence-based report. Otolaryngol Head Neck Surg 122: 1–7

    PubMed  CAS  Google Scholar 

  16. Berg O, Carenfelt C (1985) Etiological diagnosis in sinusitis: ultrasonography as clinical complement. Laryngoscope 95: 851–853

    PubMed  CAS  Google Scholar 

  17. Berg O, Carenfelt C (1988) Analysis of symptoms and clinical signs in the maxillary sinus empyema. Acta Otolaryngol 105: 343–349

    PubMed  CAS  Google Scholar 

  18. Berg O, Carenfelt C, Kronvall G (1988) Bacteriology of maxillary sinusitis in relation to character of inflammation and prior treatment. Scand J Infect Dis 20: 511–516

    PubMed  CAS  Google Scholar 

  19. Berg O, Carenfelt C, Rystedt G, Anggard A (1986) Occurrence of asymptomatic sinusitis in common cold and other acute ENT-infections. Rhinology 24: 223–225

    PubMed  CAS  Google Scholar 

  20. Berges-Gimeno P, Simon RA, Stevenson DD (2003) Long-term treatment with aspirin desensitization in asthmatic patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol 111: 180–186

    PubMed  CAS  Google Scholar 

  21. Bhattacharyya N (1999) Test-retest reliability of computed tomography in the assessment of chronic rhinosinusitis. Laryngoscope 109: 1055–1058

    PubMed  CAS  Google Scholar 

  22. Blumenthal HJ (2001) Headaches and sinus disease. Headache 41: 883–888

    PubMed  CAS  Google Scholar 

  23. Braun JJ, Alabert JP, Michel FB et al. (1997) Adjunct effect of loratadine in the treatment of acute sinusitis in patients with allergic rhinitis. Allergy 52: 650–655

    PubMed  CAS  Google Scholar 

  24. Bresciani M, Paradis L, Des RA et al. (2001) Rhinosinusitis in severe asthma. J Allergy Clin Immunol 107: 73–80

    PubMed  CAS  Google Scholar 

  25. Brook I (2001) Sinusitis – overcoming bacterial resistance. Int J Pediatr Otorhinolaryngol 58: 27–36

    PubMed  CAS  Google Scholar 

  26. Brook I, Thompson DH, Frazier EH (1994) Microbiology and management of chronic maxillary sinusitis. Arch Otolaryngol Head Neck Surg 120: 1317–1320

    PubMed  CAS  Google Scholar 

  27. Brook I, Yocum P, Frazier EH, Bartlett JG (1996) Bacteriology and beta-lactamase activity in acute and chronic maxillary sinusitis. Arch Otolaryngol Head Neck Surg 122: 418–423

    PubMed  CAS  Google Scholar 

  28. Bucher HC, Tschudi P, Young J et al. (2003) Effect of amoxicillin-clavulanate in clinically diagnosed acute rhinosinusitis: a placebo-controlled, double-blind, randomized trial in general practice. Arch Intern Med 163: 1793–1798

    PubMed  CAS  Google Scholar 

  29. Burke TF, Guertler AT, Timmons JH (1994) Comparison of sinus x-rays with computed tomography scans in acute sinusitis. Acad Emerg Med 1: 235–239

    Article  PubMed  CAS  Google Scholar 

  30. Casiano RR (1997) Correlation of clinical examination with computer tomography in paranasal sinus disease. Am J Rhinol 11: 193–196

    PubMed  CAS  Google Scholar 

  31. Cervin A, Kalm O, Sandkull P, Lindberg S (2002) One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide. Otolaryngol Head Neck Surg 126: 481–489

    PubMed  Google Scholar 

  32. Chalton R, Mackay I, Wilson R, Cole P (1985) Double blind, placebo controlled trial of betamethasone nasal drops for nasal polyposis. Br Med J (Clin Res Ed) 291: 788

    Google Scholar 

  33. Clayman GL, Adams GL, Paugh DR, Koopmann CF Jr (1991) Intracranial complications of paranasal sinusitis: a combined institutional review. Laryngoscope 101: 234–239

    PubMed  CAS  Google Scholar 

  34. Cohen BL (1998) The cancer risk from low-level radiation. Radiat Res 149: 525–528

    PubMed  CAS  Google Scholar 

  35. Crater SE, Peters EJ, Phillips CD, Platts-Mills TA (1999) Prospective analysis of CT of the sinuses in acute asthma. AJR Am J Roentgenol 173: 127–131

    PubMed  CAS  Google Scholar 

  36. Cuenant G, Stipon JP, Plante-Longchamp G et al. (1986) Efficacy of endonasal neomycin-tixocortol pivalate irrigation in the treatment of chronic allergic and bacterial sinusitis. ORL J Otorhinolaryngol Relat Spec 48: 226–232

    PubMed  CAS  Google Scholar 

  37. Cumberworth VL, Sudderick RM, Mackay IS (1994) Major complications of functional endoscopic sinus surgery. Clin Otolaryngol 19: 248–253

    PubMed  CAS  Google Scholar 

  38. Dalziel K, Stein K, Round A et al. (2003) Systematic review of endoscopic sinus surgery for nasal polyps. Health Technol Assess 7: 1–159

    Google Scholar 

  39. Damm M, Quante G, Jungehuelsing M, Stennert E (2002) Impact of functional endoscopic sinus surgery on symptoms and quality of life in chronic rhinosinusitis. Laryngoscope 112: 310–315

    PubMed  Google Scholar 

  40. Bock GH de, Dekker FW, Stolk J et al. (1997) Antimicrobial treatment in acute maxillary sinusitis: a meta-analysis. J Clin Epidemiol 50: 881–890

    PubMed  Google Scholar 

  41. Bock GH de, Houwing-Duistermaat JJ, Springer MP et al. (1994) Sensitivity and pecificity of diagnostic tests in acute maxillary sinusitis determined by maximum likelihood in the absence of an external standard. Clin Epidemiol 47: 1343–1352

    Google Scholar 

  42. Ferranti SD de, Ioannidis JP, Lau J et al. (1998) Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis. BMJ 317: 632–637

    PubMed  Google Scholar 

  43. Shazo RD de, O’Brien M, Chapin K et al. (1997) Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 99: 475–485

    Google Scholar 

  44. Desrosiers M, Ferguson B, Klossek J et al. (2006) Clinical efficacy, time to symptom resolution, and tolerability of telithromycin vs amoxicillin-clavulanate in acute bacterial sinusitis. In: Abstracts of the 46th International Conference on Antimicrobial Agents and Chemotherapy, 27–30 September, San Francisco/CA, USA; Abstract L-1448; ASM Press, Herndon/VA

  45. Dessi P, Castro F, Triglia JM et al. (1994) Major complications of sinus surgery: a review of 1192 procedures. J Laryngol Otol 108: 212–215

    PubMed  CAS  Google Scholar 

  46. Deuschl H, Drettner B (1977) Nasal polyps treated by beclomethasone nasal aerosol. Rhinology 15: 17–23

    PubMed  CAS  Google Scholar 

  47. Dolor RJ, Witsell DL, Hellkamp AS et al. (2001) Comparison of cefuroxime with or without intranasal fluticasone for the treatment of rhinosinusitis. The CAFFS Trial: a randomized controlled trial. JAMA 286: 3097–3105

    PubMed  CAS  Google Scholar 

  48. Douglas RM, Hemila H, D’Souza R et al. (2004) Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev 4: CD000980

    PubMed  Google Scholar 

  49. Dykewicz MS, Fineman S, Skoner DP et al. (1998) Diagnosis and management of rhinitis: complete guidelines of the Joint Task Force on Practice Parameters in Allergy, Asthma and Immunology. American Academy of Allergy, Asthma, and Immunology. Ann Allergy Asthma Immunol 81: 478–518

    PubMed  CAS  Google Scholar 

  50. Ebbens FA, Scadding GK, Badia L et al. (2006) Amphotericin B nasal lavages: Not a solution for patients with chronic rhinosinusitis. J Allergy Clin Immunol 118: 1149–1156

    PubMed  CAS  Google Scholar 

  51. Eccles R, Jawad MS, Morris S (1990) The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J Pharm Pharmacol 42: 652–654

    PubMed  CAS  Google Scholar 

  52. Eichner Kamprik G, Wimmer M (1987) Zur Akupunkturbehandlung bei Kindern und Erwachsenen. Akupunktur, Theorie und Praxis 15: 6–14

  53. Engels EA, Terrin N, Barza M, Lau J (2000) Meta-analysis of diagnostic tests for acute sinusitis. J Clin Epidemiol 53: 852–862

    PubMed  CAS  Google Scholar 

  54. Eufinger H, Machtens E (2001) Purulent pansinusitis, orbital cellulitis and rhinogenic intracranial complications. J Craniomaxillofac Surg 29: 111–117

    PubMed  CAS  Google Scholar 

  55. Federspil P (1991) HNO-Antibiotikatherapie: therapeutische Richtlinien (Teil I). HNO 39: 371–377

    PubMed  CAS  Google Scholar 

  56. Federspil P (1999) HNO-Antibiotikatherapie: therapeutische Richtlinien (Teil II). HNO 39: 413–418

    Google Scholar 

  57. Federspil P, Elies W, Luckhaupt H et al. (2003) Leitlinien zur Antibiotika-Therapie der bakteriellen Infektionen an Kopf und Hals. Arzneimitteltherapie 21: 162–175

    Google Scholar 

  58. Federspil P, Federspil PA (1998) Empiric, supercalculated empiric, or organism-specific therapy for otolaryngologic infections. Curr Opin Otolaryngol Head Neck Surg 6: 199–205

    Google Scholar 

  59. Federspil P, Federspil PA (2005) Antibiotikatherapie in der Hals-Nasen-Ohren-Heilkunde. HNO 53: 11–28

    PubMed  CAS  Google Scholar 

  60. Federspil P, Wulkow R, Zimmermann T (1997) Wirkung von Myrtol standardisiert bei der Therapie der akuten Sinusitis – Ergebnisse einer doppelblinden randomisierten Multicenterstudie gegen Placebo. Laryngorhinootologie 76: 23–27

    PubMed  CAS  Google Scholar 

  61. Filiaci F, Passali D, Puxeddu R, Schrewelius C (2000) A randomized controlled trial showing efficacy of once daily intranasal budesonide in nasal polyposis. Rhinology 38: 185–190

    PubMed  CAS  Google Scholar 

  62. Fokkens W, Lund V, Bachert C et al. (2005) EAACI Position paper on Rhinosinusitis and Nasal Polyposis: Executive summary. Allergy 60: 583–601

    PubMed  CAS  Google Scholar 

  63. Gaga M, Lambrou P, Papageorgiou N et al. (2000) Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis. Clin Exp Allergy 30: 663–669

    PubMed  CAS  Google Scholar 

  64. Gallagher RM, Gross CW, Phillips CD (1998) Suppurative intracranial complications of sinusitis. Laryngoscope 108: 1635–1642

    PubMed  CAS  Google Scholar 

  65. Gevaert P, Holtappels G, Johansson SGO et al. (2005) Organisation of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue. Allergy 60: 71–79

    PubMed  CAS  Google Scholar 

  66. Gold SM, Tami TA (1997) Role of middle meatus aspiration culture in the diagnosis of chronic sinusitis. Laryngoscope 107: 1586–1589

    PubMed  CAS  Google Scholar 

  67. Golusinski W, Szmeja Z, Szyfter W et al. (1996) The use of mucolytic preparations (Mucosolvan) in nasal and paranasal sinuses in children. Otolaryngol Pol 50: 599–606

    PubMed  CAS  Google Scholar 

  68. Gosepath J, Hoffmann F, Schafer D et al. (1999) Aspirin intolerance in patients with chronic sinusitis. ORL J Otorhinolaryngol Relat Spec 61: 146–150

    PubMed  CAS  Google Scholar 

  69. Gwaltney JM (1994) Microbiology of sinusitis. In: Marcel Dekker (ed), Sinusitis: Pathophysiology and treatment. Marcel Dekker, New York, pp 41–56

  70. Gwaltney JM Jr, Jones JG, Kennedy DW (1995) Medical management of sinusitis: educational goals and management guidelines. The International Conference on sinus disease. Ann Otol Rhinol Laryngol Suppl 167: 22–30

    PubMed  Google Scholar 

  71. Gwaltney JM Jr, Phillips CD, Miller RD, Riker DK (1994) Computed tomographic study of the common cold. N Engl J Med 330: 25–30

    PubMed  Google Scholar 

  72. Gwaltney JM Jr, Savolainen S, Rivas P et al. (1997) Comparative effectiveness and safety of cefdinir and amoxicillin- clavulanate in treatment of acute community-acquired bacterial sinusitis. Antimicrob Agents Chemother 41: 1517–1520

    PubMed  CAS  Google Scholar 

  73. Hackman TG, Ferguson BJ (2005) Powered instrumentation and tissue effects in the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg 13: 22–26

    PubMed  Google Scholar 

  74. Hansen JG, Schmidt H, Rosborg J, Lund E (1995) Predicting acute maxillary sinusitis in a general practice population. BMJ 311: 233–236

    PubMed  CAS  Google Scholar 

  75. Hartwig S, Linden M, Laurent C et al. (1988) Budesonide nasal spray as prophylactic treatment after polypectomy (a double blind clinical trial). J Laryngol Otol 102: 148–151

    PubMed  CAS  Google Scholar 

  76. Hashiba M, Baba S (1996) Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. Acta Otolaryngol Suppl 525: 73–78

    PubMed  CAS  Google Scholar 

  77. Heatley DG, McConnell KE, Kille TL, Leverson GE (2001) Nasal irrigation for the alleviation of sinonasal symptoms. Otolaryngol Head Neck Surg 125: 44–48

    PubMed  CAS  Google Scholar 

  78. Hedman J, Kaprio J, Poussa T, Nieminen MM (1999) Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a populationbased study. Int J Epidemiol 28: 717–722

    PubMed  CAS  Google Scholar 

  79. Hellquist HB (1996) Nasal polyps update. Histopathology. Allergy Asthma Proc 17: 237–222

    PubMed  CAS  Google Scholar 

  80. Hendley JO, Abbott RD, Beasley PP, Gwaltney JM Jr (1994) Effect of inhalation of hot humidified air on experimental rhinovirus infection. JAMA 271: 1112–1113

    PubMed  CAS  Google Scholar 

  81. Hickner JM, Bartlett JG, Besser RE et al. (2001) Principles of appropriate antibiotic use for acute Rhinosinusitis in adults: Background. Ann Intern Med 134: 498–505

    PubMed  CAS  Google Scholar 

  82. Hissaria P, Smith W, Wormald PJ et al. (2006) Short course of systemic corticosteroids in sinonasal polyposis: a double-blind, randomized, placebo-controlled trial with evaluation of outcome measures. J Allergy Clin Immunol 118: 128–133

    PubMed  CAS  Google Scholar 

  83. Holmberg K, Juliusson S, Balder B et al. (1997) Fluticasone propionate aqueous nasal spray in the treatment of nasal polyposis. Ann Allergy Asthma Immunol 78: 270–276

    PubMed  CAS  Google Scholar 

  84. Hosemann W (2001) Innere Nase und Nasennebenhöhlen. In: Strutz J, Mann W (Hrsg) Praxis der HNO-Heilkunde, Kopf- und Halschirurgie. Georg Thieme Verlag, Stuttgart New York, S 342–390

  85. Hwang PH, Irwin SB, Griest SE et al. (2003) Radiologic correlates of symptom-based diagnostic criteria for chronic rhinosinusitis. Otolaryngol Head Neck Surg 128: 489–496

    PubMed  Google Scholar 

  86. Iinuma T, Hirota Y, Kase Y (1994) Radio-opacity of the paranasal sinuses. Conventional views and CT. Rhinology 32: 134–136

    PubMed  CAS  Google Scholar 

  87. Jantii-Alanco S, Holopainen E, Malmberg H (1989) Recurrence of nasal polyps after surgical treatment. Rhinology 8: 59–64

    Google Scholar 

  88. Jones NS (2002) CT of the paranasal sinuses: a review of the correlation with clinical, surgical and histopathological findings. Clin Otolaryngol 27: 11–17

    PubMed  CAS  Google Scholar 

  89. Jones NS, Walker JL, Bassi S et al. (2002) The intracranial complications of rhinosinusitis: can they be prevented? Laryngoscope 112: 59–63

    PubMed  CAS  Google Scholar 

  90. Kaiser L, Lew D, Hirschel B et al. (1996) Effects of antibiotic treatment in the subset of common-cold patients who have bacteria in nasopharyngeal secretions. Lancet 347: 1507–1510

    PubMed  CAS  Google Scholar 

  91. Kaliner MA, Osguthorpe JD, Fireman P et al. (1997) Sinusitis: bench to bedside. Current findings, future directions. Otolaryngol Head Neck Surg 116: S1–S20

    PubMed  CAS  Google Scholar 

  92. Karlsson G, Rundcrantz H (1982) A randomized trial in intranasal beclomethasone dipropionate after polypectomy. Rhinology 20: 144–148

    PubMed  CAS  Google Scholar 

  93. Kehrl W, Sonnemann U, Dethlefsen U (2004) Therapy for acute nonpurulent rhinosinusitis with cineole: results of a double-blind, randomized, placebo-controlled trial. Laryngoscope 114: 738–742

    PubMed  Google Scholar 

  94. Keith P, Nieminen J, Hollingworth K, Dolovich J (2000) Efficacy and tolerability of fluticasone propionate nasal drops 400 microgram once daily compared with placebo for the treatment of bilateral polyposis in adults. Clin Exp Allergy 30: 1460–1468

    PubMed  CAS  Google Scholar 

  95. Keith PK, Conway M, Evans S et al. (1994) Nasal polyps: effects of seasonal allergen exposure. J Allergy Clin Immunol 93: 567–574

    PubMed  CAS  Google Scholar 

  96. Kennedy DW, Wright ED, Goldberg AN (2000) Objective and subjective outcomes in surgery for chronic sinusitis. Laryngoscope 110: 29–31

    PubMed  CAS  Google Scholar 

  97. Kenny TJ, Duncavage J, Bracikowski J et al. (2001) Prospective analysis of sinus symptoms and correlation with paranasal computed tomography scan. Otolaryngol Head Neck Surg 125: 40–43

    PubMed  CAS  Google Scholar 

  98. Kirtsreesakul V, Blair C, Yu X et al. (2004) Desloratadine partially inhibits the augmented bacterial responses in the sinuses of allergic and infected mice. Clin Exp Allergy 34: 1649–1654

    PubMed  CAS  Google Scholar 

  99. Klimek L, Bachert C (2000) Aktuelle Aspekte der nasalen Glukokortikosteroidtherapie. HNO 48: 544–555

    PubMed  CAS  Google Scholar 

  100. Klossek JM, Dubreuil L, Richet H et al. (1998) Bacteriology of chronic purulent secretions in chronic rhinosinusitis. J Laryngol Otol 112: 1162–1166

    PubMed  CAS  Google Scholar 

  101. Klossek JM, Federspil P (2005) Update on treatment guidelines for acute bacterial sinusitis. Int J Clin Pract 59: 230–238

    PubMed  CAS  Google Scholar 

  102. Knott PD, Batra PS, Citardi MJ (2006) Computer aided surgery: concepts and applications in rhinology. Otolaryngol Clin North Am 39: 503–522

    PubMed  Google Scholar 

  103. Kramer MF, Rasp G, Kastenbauer E (2003) Health related quality of life in nasal surgery. Am J Otolaryngol 24: 97–105

    PubMed  Google Scholar 

  104. Lane AP, Pine HS, Pillsbury HC 3rd (2001) Allergy testing and immunotherapy in an academic otolaryngology practice: a 20-year review. Otolaryngol Head Neck Surg 124: 9–15

    PubMed  CAS  Google Scholar 

  105. Lang S, Jager L, Grevers G (2002) Zur Aussagefähigkeit koronarer Sekundärrekonstruktionen computertomographischer Sequenzen der Nasennebenhöhlen. Laryngorhinootologie 81: 418–421

    PubMed  CAS  Google Scholar 

  106. Lange B, Bachert C (2003) Die topische intranasale Therapie der allergischen Rhinitis. Eine Wirksamkeits- und Kostenanalyse. Allergologie 26: 177–195

    Google Scholar 

  107. Lanza DC, Kennedy DW (1992) Current concepts in the surgical management of chronic and recurrent acute sinusitis. J Allergy Clin Immunol 90: 505–510

    PubMed  CAS  Google Scholar 

  108. Lanza DC, Kennedy DW (1997) Adult rhinosinusitis defined. Otolaryngol Head Neck Surg 117: S1–S7

    PubMed  CAS  Google Scholar 

  109. Larsen PL, Tingsgaard PK, Harcourt J et al. (1998) Nasal polyps and their relation to polyps/hypertrophic polypoid mucosa in the paranasal sinuses: a macro-, endo-, and microscopic study of autopsy materials. Am J Rhinol 12: 45–51

    PubMed  CAS  Google Scholar 

  110. Larsen PL, Tos M (1991) Origin of nasal polyps. Laryngoscope 101: 305–312

    PubMed  CAS  Google Scholar 

  111. Legent F, Bordure P, Beauvillain C, Berche P (1994) A double-blind comparison of ciprofloxacin and amoxycillin/clavulanic acid in the treatment of chronic sinusitis. Chemotherapy (Suppl 1) 40: 8–15

    Google Scholar 

  112. Lewison E (1970) Comparison of the effectiveness of topical and oral nasal decongestants. Eye Ear Nose Throat Mon 49: 16–18

    PubMed  CAS  Google Scholar 

  113. Leynaert B, Neukirch F, Demoly P, Bousquet J (2000) Epidemiologic evidence for asthma and rhinitis comorbidity. J Allergy Clin Immunol 106: S201–S205

    PubMed  CAS  Google Scholar 

  114. Lildholdt T, Rundcrantz H, Bende M, Larsen K (1997) Glucocorticoid treatment for nasal polyps. The use of topical budesonide powder, intramuscular betamethasone, and surgical treatment. Arch Otolaryngol Head Neck Surg 123: 595–600

    PubMed  CAS  Google Scholar 

  115. Lildholdt T, Rundcrantz H, Lindqvist N (1995) Efficacy of topical corticosteroid powder for nasal polyps: a double-blind, placebo-controlled study of budesonide. Clin Otolaryngol 20: 26–30

    PubMed  CAS  Google Scholar 

  116. Lindbaek M, Hjortdahl P, Johnsen UL (1996) Use of symptoms, signs, and blood tests to diagnose acute sinus infections in primary care: comparison with computed tomography. Fam Med 28: 183–188

    PubMed  CAS  Google Scholar 

  117. Low DE, Desrosiers M, McSherry J et al. (1997) A practical guide for the diagnosis and treatment of acute sinusitis. CMAJ (Suppl 6) 156: S1–S14

  118. Lund VJ, Flood J, Sykes AP, Richards DH (1998) Effect of fluticasone in severe polyposis. Arch Otolaryngol Head Neck Surg 124: 513–518

    PubMed  CAS  Google Scholar 

  119. Lund VJ, Holmstrom M, Scadding GK (1991) Functional endoscopic sinus surgery in the management of chronic rhinosinusitis. An objective assessment. J Laryngol Otol 105: 832–835

    PubMed  CAS  Google Scholar 

  120. Lund VJ, Kennedy DW (1995) Quantification for staging sinusitis. The Staging and Therapy Group. Ann Otol Rhinol Laryngol Suppl 167: 17–21

    PubMed  CAS  Google Scholar 

  121. Lund VJ, Kennedy DW (1997) Staging for rhinosinusitis. Otolaryngol Head Neck Surg 117: S35–S40

    PubMed  CAS  Google Scholar 

  122. Lund VJ, Scadding GK (1994) Objective assessment of endoscopic sinus surgery in the management of chronic rhinosinusitis: an update. J Laryngol Otol 108: 749–753

    PubMed  CAS  Google Scholar 

  123. Lundeberg T, Laurell G, Thomas M (1988) Effect of acupuncture on sinus pain and experimentally induced pain. Ear Nose Throat J 67: 565–562

    PubMed  CAS  Google Scholar 

  124. Macbeth R (1971) Caldwell, Luc, and their operation. Laryngoscope 81: 1652–1657

    PubMed  CAS  Google Scholar 

  125. Marianowski R, Forcioli J, Bouhnik M et al. (2001) Intracranial complications of ethmoiditis evidenced by magnetic resonance imaging. Ann Otol Rhinol Laryngol 110: 592–595

    PubMed  CAS  Google Scholar 

  126. Marshall I (2000) Zinc for the common cold. Cochrane Database Syst Rev 2: CD001364

    PubMed  Google Scholar 

  127. McAlister WH, Lusk R, Munz HR (1989) Comparison of plain radiographs and coronal CT scans in infants and children with recurrent sinusitis. AJR Am J Roentgenol 153: 1259–1264

    PubMed  CAS  Google Scholar 

  128. McCormick DP, John SD, Swischuk LE, Uchida T (1996) A double-blind, placebo-controlled trial of decongestant-antihistamine for the treatment of sinusitis in children. Clin Pediatr (Phila) 35: 457–460

    Google Scholar 

  129. Melchart D, Linde K, Fischer P, Kaesmayr J (2000) Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev 2: CD000530

    PubMed  Google Scholar 

  130. Meltzer EO, Charous BL, Busse WW et al. (2000) Added relief in the treatment of acute recurrent sinusitis with adjunctive mometasone furoate nasal spray. The Nasonex Sinusitis Group. J Allergy Clin Immunol 106: 630–637

    PubMed  CAS  Google Scholar 

  131. Meltzer EO, Hamilos DL, Hadley JA et al. (2004) Rhinosinusitis: Establishing definitions for clinical research and patient care. Otolaryngol Head Neck Surg (Suppl 6) 131: S1–S62

    Google Scholar 

  132. Meltzer EO, Orgel HA, Backhaus JW et al. (1993) Intranasal flunisolide spray as an adjunct to oral antibiotic therapy for sinusitis. J Allergy Clin Immunol 92: 812–823

    PubMed  CAS  Google Scholar 

  133. Messerklinger W (1970) [Endoscopy of the nose]. Monatsschr Ohrenheilkd Laryngorhinol 104: 451–456

    PubMed  CAS  Google Scholar 

  134. Messerklinger W (1972) Nasenendoskopie: Der mittlere Nasengang und seine unspezifischen Entzündungen. HNO 20: 212–215

    PubMed  CAS  Google Scholar 

  135. Metson RB, Gliklich RE (2000) Clinical outcomes in patients with chronic sinusitis. Laryngoscope 110: 24–28

    PubMed  CAS  Google Scholar 

  136. Milewski M, Mastalerz L, Nilzankowska E (1998) Nasal provocation test with lysineaspirin for diagnosis of aspirin-sensitive asthma. J Allergy Clin Immunol 101: 581–586

    PubMed  CAS  Google Scholar 

  137. Mösges R, Spaeth J, Berger K, Dubois F (2002) Topical treatment of rhinosinusitis with fusafungine nasal spray. A double-blind, placebo-controlled, parallel-group study in 20 patients. Arzneimittelforschung 52: 877–883

    PubMed  Google Scholar 

  138. Muntz HR, Lusk RP (1991) Bacteriology of the ethmoid bullae in children with chronic sinusitis. Arch Otolaryngol Head Neck Surg 117: 179–181

    PubMed  CAS  Google Scholar 

  139. Mygind N, Dahl R, Nielsen LP et al. (1997) Effect of corticosteroids on nasal blockage in rhinitis measured by objective methods. Allergy (Suppl 40) 52: 39–44

    Google Scholar 

  140. Namyslowski G, Misiolek M, Czecior E et al. (2002) Comparison of the efficacy and tolerability of amoxycillin/clavulanic acid 875 mg b.i.d. with cefuroxime 500 mg b.i.d. in the treatment of chronic and acute exacerbation of chronic sinusitis in adults. J Chemother 14: 508–517

    PubMed  CAS  Google Scholar 

  141. Nayak AS, Settipane GA, Pedinoff A et al. (2002) Effective dose range of mometasone furoate nasal spray in the treatment of acute rhinosinusitis. Ann Allergy Asthma Immunol 89: 271–278

    PubMed  CAS  Google Scholar 

  142. Neubauer N, März RW (1994) Placebo-controlled, randomized double-blind clinical trial with Sinupret sugar-coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1: 177–181

    Google Scholar 

  143. Newman LJ, Platts-Mills TA, Phillips CD et al. (1994) Chronic sinusitis. Relationship of computed tomographic findings to allergy, asthma, and eosinophilia. JAMA 271: 363–367

    PubMed  CAS  Google Scholar 

  144. Nizankowska E, Duplaga M, Bochenek G et al. (1998) Clinical course of aspirininduced asthma: results of AIANE. In: Szczeklik A, Gryglewski R, Vane J (eds) Eicosanoids, aspirin and asthma. Marcel Dekker, New York, pp 451–471

  145. Ophir D, Elad Y (1987) Effects of steam inhalation on nasal patency and nasal symptoms in patients with the common cold. Am J Otolaryngol 8: 149–153

    PubMed  CAS  Google Scholar 

  146. Orobello PW Jr, Park RI, Belcher LJ et al. (1991) Microbiology of chronic sinusitis in children. Arch Otolaryngol Head Neck Surg 117: 980–983

    PubMed  Google Scholar 

  147. Osguthorpe JD (2001) Adult rhinosinusitis: diagnosis and management. Am Fam Physician 63: 69–76

    PubMed  CAS  Google Scholar 

  148. Pang YT, Willatt DJ (1996) Do antral washouts have a place in the current management of chronic sinusitis? J Laryngol Otol 110: 926–928

    PubMed  CAS  Google Scholar 

  149. Parikh AA, Scadding GK (2005) Intranasal lysine-aspirin in aspirin-sensitive nasal polyposis: a controlled trial. Laryngoscope 115: 1385–1390

    PubMed  CAS  Google Scholar 

  150. Patriarca G, Bellioni P, Nucera E et al. (1991) Intranasal treatment with lysine acetyl-salicylate in patients with nasal polyposis. Ann Allergy 67: 588–592

    PubMed  CAS  Google Scholar 

  151. Pelausa EO, Smith K, Dempsey I (1995) Orbital complications of functional endoscopic sinus surgery. J Otolaryngol 24: 154–159

    PubMed  CAS  Google Scholar 

  152. Pelikan Z, Pelikan-Filipek M (1990) Role of nasal allergy in chronic maxillary sinusitis–diagnostic value of nasal challenge with allergen. J Allergy Clin Immunol 86: 484–491

    PubMed  CAS  Google Scholar 

  153. Penttilae M, Poulsen P, Hollingworth K, Holmstroem M (2000) Dose-related efficacy and tolerability of fluticasone propionate nasal drops 400 microg once daily and twice daily in the treatment of bilateral nasal polyposis: a placebo-controlled randomized study in adult patients. Clin Exp Allergy 30: 94–102

    Google Scholar 

  154. Pfaar O, Klimek L (2006) Aspirin desensitization in aspirin intolerance: update on current standards and recent improvements. Curr Opin Allergy Clin Immunol 6: 161–166

    PubMed  CAS  Google Scholar 

  155. Pfaar O, Spielhaupter M, Wrede H et al. (2006) Adaptive Desaktivierung bei ASS-intoleranten Patienten mit Polyposis nasi et sinuum. Allergologie 29: 322–332

    Google Scholar 

  156. Pfister R, Lutolf M, Schapowal A et al. (1994) Screening for sinus disease in patients with asthma: a computed tomography-controlled comparison of A-mode ultrasonography and standard radiography. J Allergy Clin Immunol 94: 804–809

    PubMed  CAS  Google Scholar 

  157. Picado C, Mullol J (1998) The nose in aspirin-sensitive asthma. In: Szczeklik A, Gryglewski RJ, Vane J (eds) Eicosanois, aspirin and asthma. Marcel Dekker, New York, pp 493–505

  158. Piccirillo JF, Mager DE, Frisse ME et al. (2001) Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis. JAMA 286: 1849–1856

    PubMed  CAS  Google Scholar 

  159. Pleis JR, Coles R (2002) Summary health statistics for U.S. adults: National Health Interview Survey, 1998. Vital Health Stat 10, 209: 1–113

  160. Ponikau JU, Sherris DA, Kern EB et al. (1999) The diagnosis and incidence of allergic fungal sinusitis. Mayo Clin Proc 74: 877–884

    PubMed  CAS  Google Scholar 

  161. Ponikau JU, Sherris DA, Weaver A, Kita H (2005) Treatment of chronic rhinosinusitis with intranasal amphotericin B: a randomized, placebo-controlled, double-blind pilot trial. J Allergy Clin Immunol 115: 125–131

    PubMed  CAS  Google Scholar 

  162. Qvarnberg Y, Kantola O, Salo J et al. (1992) Influence of topical steroid treatment on maxillary sinusitis. Rhinology 30: 103–112

    PubMed  CAS  Google Scholar 

  163. Rabago D, Zgierska A, Mundt M et al. (2002) Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: a randomized controlled trial. J Fam Pract 51: 1049–1055

    PubMed  Google Scholar 

  164. Ragab SM, Lund VJ, Scadding G (2004) Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial. Laryngoscope 114: 923–930

    PubMed  Google Scholar 

  165. Ramadan HH (1995) What is the bacteriology of chronic sinusitis in adults? Am J Otolaryngol 16: 303–306

    PubMed  CAS  Google Scholar 

  166. Rasp G, Kramer MF, Ostertag P, Kastenbauer E (2000) Ein neues System zur Einteilung der Siebbeinpolyposis. Laryngorhinootologie 79: 266–272

    PubMed  CAS  Google Scholar 

  167. Ray NF, Baraniuk JN, Thamer M et al. (1999) Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders. J Allergy Clin Immunol 103: 408–414

    PubMed  CAS  Google Scholar 

  168. Rohr AS, Spector SL, Siegel SC et al. (1986) Correlation between A-mode ultrasound and radiography in the diagnosis of maxillary sinusitis. J Allergy Clin Immunol 78: 58–61

    PubMed  CAS  Google Scholar 

  169. Rosbe KW, Jones KR (1998) Usefulness of patient symptoms and nasal endoscopy in the diagnosis of chronic sinusitis. Am J Rhinol 12: 167–171

    PubMed  CAS  Google Scholar 

  170. Roseler St, Bachert C, Wagenmann M, Holtappels G (1995) Elevated levels of cytokines in viral rhinitis. Eur Arch Otorhinolaryngol 252: S61–S63

    PubMed  Google Scholar 

  171. Rossberg E, Larsson PG, Birkeflet O, Soholt LE (2005) Comparison of traditional Chinese acupuncture, minimal acupuncture at non-acupoints and conventional treatment for chronic sinusitis. Complement Ther Med 13: 4–10

    PubMed  CAS  Google Scholar 

  172. Rudack C, Hauser U, Wagenmann N et al. (1998) Zytokinmuster bei verschiedenen Formen der Nasennebenhöhlenentzündungen. Laryngorhinootologie 77: 34–37

    PubMed  CAS  Google Scholar 

  173. Rudack C, Stoll W, Bachert C (1998) Cytokines in nasal polyposis, acute and chronic sinusitis. Am J Rhinol 12: 383–388

    PubMed  CAS  Google Scholar 

  174. Ruhno J, Andersson B, Denburg J et al. (1990) A double-blind comparison of intranasal budesonide with placebo for nasal polyposis. J Allergy Clin Immunol 86: 946–953

    PubMed  CAS  Google Scholar 

  175. Ruoppi P, Seppa J, Nuutinen J (1993) Acute frontal sinusitis: etiological factors and treatment outcome. Acta Otolaryngol 113: 201–205

    PubMed  CAS  Google Scholar 

  176. Samter M, Beers RF (1968) Intolerance to aspirin. Clinical studies and consideration of its pathogenesis. Ann Intern Med 68: 975–983

    PubMed  CAS  Google Scholar 

  177. Savolainen S, Jousimies-Somer H, Kleemola M, Ylikoski J (1989) Serological evidence of viral or Mycoplasma pneumoniae infection in acute maxillary sinusitis. Eur J Clin Microbiol Infect Dis 8: 131–135

    PubMed  CAS  Google Scholar 

  178. Schmitz-Schumann M, Schaub E, Virchow C (1982) Inhalation provocations testwith lysine-acetyl-salicylic acid in patients with analgetics-induced asthma. Prax Klin Pneumol 36: 17–21

    PubMed  CAS  Google Scholar 

  179. Seltzer AP (1967) Adjunctive use of bromelains in sinusitis: a controlled study. Eye Ear Nose Throat Mon 46: 1281–1288

    PubMed  CAS  Google Scholar 

  180. Senior BA, Kennedy DW, Tanabodee J et al. (1998) Long-term results of functional endoscopic sinus surgery. Laryngoscope 108: 151–157

    PubMed  CAS  Google Scholar 

  181. Settipane GA (1996) Nasal polyps and immunoglobulin E (IgE). Allergy Asthma Proc 17: 269–273

    PubMed  CAS  Google Scholar 

  182. Settipane RA, Lieberman P (2001) Update on nonallergic rhinitis. Ann Allergy Asthma Immunol 86: 494–507

    Article  PubMed  CAS  Google Scholar 

  183. Shapiro GG, Furukawa CT, Pierson WE et al. (1986) Blinded comparison of maxillary sinus radiography and ultrasound for diagnosis of sinusitis. J Allergy Clin Immunol 77: 59–64

    PubMed  CAS  Google Scholar 

  184. Sindwani R, Bucholz RD (2005) The next generation of navigational technology. Otolaryngol Clin North Am 38: 551–562

    PubMed  Google Scholar 

  185. Slavin RG (1992) Asthma and sinusitis. J Allergy Clin Immunol 90: 534–537

    PubMed  CAS  Google Scholar 

  186. Spector SL, Bernstein IL, Li JT et al. (1998) Parameters for the diagnosis and management of sinusitis. J Allergy Clin Immunol 102: S107–S144

    PubMed  CAS  Google Scholar 

  187. Stammberger H (1992) Spezifische Erkrankungen der äußeren und inneren Nase sowie der Nebenhöhlen-Mykosen. In: Naumann HH, Helms J, Herberhold C, Kastenbauer E (Hrsg) Oto-Rhino-Laryngologie in Klinik und Praxis. Thieme Verlag, Stuttgart New York, S 151–163

  188. Stammberger H (1994) The evolution of functional endoscopic sinus surgery. Ear Nose Throat J 73: 451; 454–455

    PubMed  CAS  Google Scholar 

  189. Stammberger H, Posawetz W (1990) Functional endoscopic sinus surgery. Concept, indications and results of the Messerklinger technique. Eur Arch Otorhinolaryngol 247: 63–76

    PubMed  CAS  Google Scholar 

  190. Stankiewicz JA (1997) Chronic sinusitis. In: Johnson JT, Yu VL (eds) Infectious Diseases and Antimicrobial Therapy of the Ears, Nose and Throat. W.B. Saunders Company, Philadelphia, pp 350–360

  191. Stankiewicz JA, Chow JM (2002) A diagnostic dilemma for chronic rhinosinusitis: definition accuracy and validity. Am J Rhinol 16: 199–202

    PubMed  Google Scholar 

  192. Stevenson DD, Hankammer MA, Mathison DA et al. (1996) Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: long-term outcomes. J Allergy Clin Immunol 98: 751–758

    PubMed  CAS  Google Scholar 

  193. Stevenson DD, Pleskow WW, Simon RA et al. (1984) Aspirin-sensitive rhinosinusitis asthma: a double blind cross over studyof treatment with aspirin. J Allergy Clin Immunol 73: 500–507

    PubMed  CAS  Google Scholar 

  194. Stevenson DD, Simon RA, Mathison DA (1980) Aspirin-sensitive asthma: tolerance to aspirin after positive oral aspirin challenges. J Allergy Clin Immunol 66: 82–88

    PubMed  CAS  Google Scholar 

  195. Strauss G, Koulechov K, Richter R et al. (2005) Navigated Control: Ein neues Konzept für die Computer-Assistierte-HNO-Chirurgie. Laryngorhinootologie 84: 567–576

    PubMed  CAS  Google Scholar 

  196. Sweet JM, Stevenson DD, Simon RA, Mathison DA (1990) Long-term effects of aspirin desensitization – treatment for aspirine-sensitive rhinosinusitis-asthma. J Allergy Clin Immunol 85: 59–65

    PubMed  CAS  Google Scholar 

  197. Sykes DA, Wilson R, Chan KL et al. (1986) Relative importance of antibiotic and improved clearance in topical treatment of chronic mucopurulent rhinosinusitis. A controlled study. Lancet 2: 359–360

    PubMed  CAS  Google Scholar 

  198. Szczeklik A, Nizankowska E (2000) Clinical features and diagnosis of aspirin induced asthma. Thorax (Suppl 2) 55: S42–S44

  199. Szczeklik A, Sanak M, Niz E, Kielbasa B (2004) Aspirin intolerance and the cyclooxygenase–leukotriene pathways. Curr Opin Pulm Med 10: 51–56

    PubMed  CAS  Google Scholar 

  200. Szczeklik A, Stevenson DD (2003) Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J Allergy Clin Immunol 111: 913–921

    PubMed  CAS  Google Scholar 

  201. Taccariello M, Parikh A, Darby Y, Scadding G (1999) Nasal douching as a valuable adjunct in the management of chronic rhinosinusitis. Rhinology 37: 29–32

    PubMed  CAS  Google Scholar 

  202. Takeuchi H, Jawad MS, Eccles R (1999) The effects of nasal massage of the „yingxiang“ acupuncture point on nasal airway resistance and sensation of nasal airflow in patients with nasal congestion associated with acute upper respiratory tract infection. Am J Rhinol 13: 77–79

    PubMed  CAS  Google Scholar 

  203. Talbot AR, Herr TM, Parsons DS (1997) Mucociliary clearance and buffered hypertonic saline solution. Laryngoscope 107: 500–503

    PubMed  CAS  Google Scholar 

  204. Tantilipikorn P, Fritz M, Tanabodee J et al. (2002) A comparison of endoscopic culture techniques for chronic rhinosinusitis. Am J Rhinol 16: 255–260

    PubMed  Google Scholar 

  205. Taub SJ (1967) The use of bromelains in sinusitis: a double-blind clinical evaluation. Eye Ear Nose Throat Mon 46: 361

    PubMed  CAS  Google Scholar 

  206. Taverner D, Latte J, Draper M (2004) Nasal decongestants for the common cold. Cochrane Database Syst Rev 3: CD001953

    PubMed  Google Scholar 

  207. Brinke A ten, Grootendorst DC, Schmidt JT et al. (2002) Chronic sinusitis in severe asthma is related to sputum eosinophilia. J Allergy Clin Immunol 109: 621–626

    PubMed  Google Scholar 

  208. Togias A (2003) Rhinitis and asthma: Evidence for respiratory system integration. J Allergy Clin Immunol 111: 1171–1183

    PubMed  Google Scholar 

  209. Tomooka LT, Murphy C, Davidson TM (2000) Clinical study and literature review of nasal irrigation. Laryngoscope 110: 1189–1193

    PubMed  CAS  Google Scholar 

  210. Tos M, Svendstrup F, Arndal H et al. (1998) Efficacy of an aqueous and a powder formulation of nasal budesonide compared in patients with nasal polyps. Am J Rhinol 12: 183–189

    PubMed  CAS  Google Scholar 

  211. Tyrrell D, Barrow I, Arthur J (1989) Local hyperthermia benefits natural and experimental common colds. BMJ 298: 1280–1283

    Article  PubMed  CAS  Google Scholar 

  212. Buchem L van, Peeters M, Beaumont J, Knottnerus JA (1995) Acute maxillary sinusitis in general practice: the relation between clinical picture and objective findings. Eur J Gen Pract 1: 155–160

    Article  Google Scholar 

  213. Camp C van, Clement PA (1994) Results of oral steroid treatment in nasal polyposis. Rhinology 32: 5–9

    PubMed  Google Scholar 

  214. Zele T van, Claeys S, Gevaert P et al. (2006) Differentiation of chronic sinus diseases by measurement of inflammatory mediators. Allergy 61: 1280–1289

    PubMed  Google Scholar 

  215. Zele T van, Gevaert P, Watelet JB et al. (2004) Staphylococcus aureus colonization and IgE antibody formation to enterotoxins is increased in nasal polyposis. J Allergy Clin Immunol 114: 981–983

    PubMed  Google Scholar 

  216. Varonen H, Makela M, Savolainen S et al. (2000) Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. J Clin Epidemiol 53: 940–948

    PubMed  CAS  Google Scholar 

  217. Vickers AJ, Rees RW, Zollman CE et al. (2004) Acupuncture for chronic headache in primary care. BMJ 328: 744

    PubMed  Google Scholar 

  218. Virolainen E, Puhakka H (1980) The effect of intranasal beclomethasone dipropionate on the recurrence of nasal polyps after ethmoidectomy. Rhinology 18: 9–18

    PubMed  CAS  Google Scholar 

  219. Vleming M, Middelweerd RJ, Vries N de (1992) Complications of endoscopic sinus surgery. Arch Otolaryngol Head Neck Surg 118: 617–623

    PubMed  CAS  Google Scholar 

  220. Wagenmann M (2004) Die allergische Pilzsinusitis. In: Schultze-Werninghaus G, Fuchs T, Bachert C, Wahn U (Hrsg) Manuale allergologicum. Teil 2, Dustri Verlag, Oberhaching, S 825–840

  221. Weschta M, Rimek D, Formanek M et al. (2004) Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: a randomized, double-blind clinical trial. J Allergy Clin Immunol 113: 1122–1128

    PubMed  CAS  Google Scholar 

  222. West B, Jones NS (2001) Endoscopy-negative, computed tomography-negative facial pain in a nasal clinic. Laryngoscope 111: 581–586

    PubMed  CAS  Google Scholar 

  223. White PS, Maclennan AC, Connolly AA et al. (1996) Analysis of CT scanning referrals for chronic rhinosinusitis. J Laryngol Otol 110: 641–643

    PubMed  CAS  Google Scholar 

  224. Wiklund L, Stierna P, Berglund R et al. (1994) The efficacy of oxymetazoline administered with a nasal bellows container and combined with oral phenoxymethyl-penicillin in the treatment of acute maxillary sinusitis. Acta Otolaryngol Suppl 515: 57–64

    PubMed  CAS  Google Scholar 

  225. Williams JW Jr, Aguilar C, Cornell J et al. (2003) Antibiotics for acute maxillary sinusitis. Cochrane Database Syst Rev 2: CD000243

    PubMed  Google Scholar 

  226. Williams JW Jr, Aguilar C, Makela M, Sparandero F (2000) Penicillin V or amoxicillin is better than placebo and equal to non-penicillins for acute maxillary sinusitis. Evid Based Med 5: 43

    Google Scholar 

  227. Williams JW Jr, Simel DL (1993) Does this patient have sinusitis? Diagnosing acute sinusitis by history and physical examination. JAMA 270: 1242–1246

    PubMed  Google Scholar 

  228. Williams JW Jr, Simel DL, Roberts L, Samsa GP (1992) Clinical evaluation for sinusitis. Making the diagnosis by history and physical examination. Ann Intern Med 117: 705–710

    PubMed  Google Scholar 

  229. Winther B, Gwaltney JM, Hendley JO (1990) Respiratory virus infection of monolayer cultures of human nasal epithelial cells. Am Rev Respir Dis 141: 839–845

    PubMed  CAS  Google Scholar 

  230. Zeiss CR, Lockey RF (1976) Refractory period to aspirin in a patient with aspirin-induced asthma. J Allergy Clin Immunol 57: 440–448

    PubMed  CAS  Google Scholar 

  231. Zhang N, Gevaert P, Zele T van et al. (2005) An update on the impact of Staphylococcus aureus enterotoxins in chronic sinusitis with nasal polyposis. Rhinology 43: 162–168

    PubMed  CAS  Google Scholar 

  232. Zinreich SJ, Kennedy DW, Rosenbaum AE et al. (1987) Paranasal sinuses: CT imaging requirements for endoscopic surgery. Radiology 163: 769–775

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Universitäts-HNO-Klinik Mannheim, 68135, Mannheim, Deutschland

    B.A. Stuck, L. Klimek, O. Pfaar & K. Hörmann

  2. Kliniek voor Neus-, Keel- & Oorheelkunde, UZ Gent, Gent, Belgien

    C. Bachert

  3. Akazienweg 1, 66424, Homburg/S., Deutschland

    P. Federspil

  4. Universitäts-HNO-Klinik, Greifswald, Deutschland

    W. Hosemann

  5. Zentrum für Rhinologie und Allergologie, Wiesbaden, Deutschland

    L. Klimek & O. Pfaar

  6. Institut für Medizinische Statistik, Informatik und Epidemiologie, Universität zu Köln, Köln, Deutschland

    R. Mösges

  7. Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Universitätsklinikum, Münster, Deutschland

    C. Rudack

  8. Institut für Theoretische Chirurgie, Marburg, Deutschland

    H. Sitter

  9. Hals, Nasen- und Ohrenklinik, Universitätsklinikum, Düsseldorf, Deutschland

    M. Wagenmann

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Anhang

Anhang

Termine und Teilnehmer der nominalen Gruppenprozesse und des Delphi-Verfahrens

Der ersten nominale Gruppenprozess fand am 22. und 23.11.2002 unter der Leitung von Herrn PD Dr. med. H. Sitter (Institut für Theoretische Chirurgie, Marburg) unter Beteiligung verschiedener Fachvertreter in Mannheim statt. Die Teilnehmer waren im Einzelnen: Frau PD Dr. med. S. Kösling (Arbeitsgemeinschaft Kopf-Hals Diagnostik der Deutschen Gesellschaft für Radiologie), Frau V. B. Nau (Vorstandssprecherin des Dachverbandes der Patientenorganisationen zu Allergien, Atemwegserkrankungen und Neurodermitis), Frau Prof. Dr. med. C. Rudack (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. W. Hosemann (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. K. Hörmann (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Dr. med. H.-U. Homoth (Deutscher Berufsverband der Hals-Nasen-Ohren-Ärzte e. V.), Dr. med. D. Jobst (Deutsche Gesellschaft für Allgemeinmedizin), Prof. Dr. med. L. Klimek (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), PD Dr. med. G. Marklein (Medizinische Mikrobiologie und Immunologie), Prof. Dr. med. Dipl.-Ing. R. Mösges (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Dr. med. U. Popert (Deutsche Gesellschaft für Allgemeinmedizin), Dr. med. M. Rose (Kinderheilkunde und Jugendmedizin), Prof. Dr. med. B. A. Stuck (Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde), Prof. Dr. med. S. Zielen (Kinderheilkunde und Jugendmedizin).

Der zweite nominale Gruppenprozess fand am 27. und 28.11.2006 unter Beteiligung der folgenden fachärztlichen Vertreter unter Leitung von Herrn PD Dr. med. H. Sitter (Institut für Theoretische Chirurgie, Marburg) in Mannheim statt: Prof. Dr. med. P. Federspil, Prof. Dr. med. K. Hörmann, Prof. Dr. med. L. Klimek, Prof. Dr. med. Dipl. Ing. R. Mösges, Dr. med. O. Pfaar, Prof. Dr. med. C. Rudack, Prof. Dr. med. B. A. Stuck und PD Dr. med. M. Wagenmann.

Am abschließenden Delphi-Verfahren waren sämtliche Autoren der Leitlinie beteiligt: Prof. Dr. med. C. Bachert, Prof. Dr. med. P. Federspil, Prof. Dr. med. K. Hörmann, Prof. Dr. med. W. Hosemann, Prof. Dr. med. L. Klimek, Prof. Dr. med. Dipl. Ing. R. Mösges, Dr. med. O. Pfaar, Prof. Dr. med. C. Rudack, Prof. Dr. med. B. A. Stuck und PD Dr. med. M. Wagenmann.

Finanzierung und Interessenkonflikte

Die Leitlinie wurde ohne externe Finanzierung und ausschließlich mit den Finanzmitteln der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie entwickelt.

Als Gegenstand möglicher Interessenkonflikte bei der Erstellung der Leitlinie könnte angesehen werden, dass verschiedenste Forschungsarbeiten der beteiligten Autoren von zahlreichen Unternehmen unterstützt wurden. Die Autoren erklären jedoch zusammenfassend ihre wirtschaftliche Unabhängigkeit bei der Erstellung der oben genannten Leitlinie.

Verabschiedung der Leitlinie

Die vorliegende Fassung der Leitlinie wurde 15.05.2007 vom Präsidium der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie beraten und angenommen.

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Stuck, B., Bachert, C., Federspil, P. et al. Leitlinie „Rhinosinusitis“ der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie. HNO 55, 758–777 (2007). https://doi.org/10.1007/s00106-007-1589-6

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