Skip to main content
Log in

Das seltene Sialadenoma papilliferum am harten Gaumen

Fallbericht und Literaturübersicht

Rare sialadenoma papilliferum in the hard palate

Case report and survey of the literature

  • Kasuistiken
  • Published:
HNO Aims and scope Submit manuscript

Zusammenfassung

Das Sialadenoma papilliferum stellt einen seltenen benignen Tumor der Speicheldrüsen dar, der typischerweise in der Mundhöhle lokalisiert ist. Als Hauptlokalisationen werden, entsprechend der Verteilung der kleinen Speicheldrüsen in der Mundschleimhaut, der harte und weiche Gaumen genannt. In der Literatur finden sich wenige Kasuistiken zu dieser Tumorentität. Es wird der Fall eines 63-jährigen Patienten beschrieben, bei dem das Sialadenoma papilliferum im Rahmen einer hals-, nasen-, ohrenärztlichen Untersuchung zur Abklärung einer progredienten Dysphagie zufällig diagnostiziert wurde. Bei dem Patienten bestand ein Zustand nach Ösophagektomie bei infrabifurkalem Ösophaguskarzinom ein Jahr zuvor. Die histologische Sicherung erfolgte durch eine Biopsie am Übergang vom harten zum weichen Gaumen rechts. Der Fall wird mit 39 weiteren Kasuistiken aus der Literatur verglichen. Die Therapie der Wahl stellt die chirurgische Resektion des Tumors dar. Hierbei sollte eine In-sano-Resektion angestrebt werden, da in der Literatur eine hohe Rezidivrate bei unvollständiger Entfernung beschrieben wird.

Abstract

Sialadenoma papilliferum is a rare tumour of the salivary glands that usually occurs in the oral cavity. Following the course of the salivary glands of the oral mucosa, the hard and soft palate are the most common locations of this tumor. In the international literature, only a few case reports about this entity can be found. We present a 63-year-old patient with a sialadenoma papilliferum accidentally found during diagnostic procedures for progredient dysphagia. Suffering from infrabifurcal cancer of the oesophagus, the patient had undergone partial oesophagectomy 1 year before. Histological verification was performed with a tumor biopsy at the border of hard and soft palate, on the right side. This case is compared with 39 further cases reported in the literature. The therapy of choice is resection of the tumor. Because of the high frequency of recurrence, in sano resection should be planned.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. Abrams AM, Finck FM (1969) Sialadenoma papilliferum. A previously unreported salivary gland tumor. Cancer 24 (5): 1057–1063

    Article  PubMed  CAS  Google Scholar 

  2. Argyres MI, Golitz LE (1999) Sialadenoma papilliferum of the palate: case report and literature review. J Cutan Pathol 26: 259–262

    Article  PubMed  CAS  Google Scholar 

  3. Asahina I, Abe M (1997) Sialadenoma papilliferum of the hard palate: a case report and review of the literature. J Oral Maxillofac Surg 55 (9): 1000–1003

    Article  PubMed  CAS  Google Scholar 

  4. Bass KD, Cosentino BJ (1985) Sialadenoma papilliferum. J Oral Maxillofac Surg 43 (4): 302–304

    Article  PubMed  CAS  MathSciNet  Google Scholar 

  5. Castigliano SG, Gold L (1954) Intraductal papilloma of the hard palate. Oral Surg 7: 232

    Article  PubMed  CAS  Google Scholar 

  6. Chan KW, Ng WL, Lau WF (1985) Sialadenoma papilliferum. Pathology 17 (1): 119–122

    Article  PubMed  CAS  Google Scholar 

  7. Cleary KR, Batsakis JG (1990) Sialadenoma papilliferum. Ann Otol Rhinol Laryngol 99(9Pt1): 756–758

    PubMed  CAS  Google Scholar 

  8. Crocker DJ, Christ TF, Cavalaris CJ (1972) Sialadenoma papilliferum: report of case. J Oral Surg 30 (7): 520–521

    PubMed  CAS  Google Scholar 

  9. Drummond JF, Giansanti JS, Sabes WR, Smith CR (1978) Sialadenoma papilliferum of the oral cavity. Oral Surg Oral Med Oral Pathol 45 (1): 72–75

    Article  PubMed  CAS  Google Scholar 

  10. Ellis GL, Auclair PL (1991) Ductal papillomas. In: Ellis GL, Auclair PL, Grepp DR (eds) Surgical pathology of the salivary glands. W.B.Saunders, Philadelphia, S. 238

  11. Fantasia JE, Nocco CE, Lally ET (1986) Ultrastructure of sialadenoma papilliferum. Arch Pathol Lab Med 110 (6): 523–527

    PubMed  CAS  Google Scholar 

  12. Freedman PD, Lumerman H (1978) Sialadenoma papilliferum. Oral Surg Oral Med Oral Pathol 45 (1): 88–94

    Article  PubMed  CAS  Google Scholar 

  13. Grushka M, Podoshin L, Boss JH et al. (1984) Sialadenoma papilliferum of the parotid gland. Laryngoscope 94: 231

    Article  PubMed  CAS  Google Scholar 

  14. Jensen JL, Reingold IM (1973) Sialadenoma papilliferum at the oral cavity. Report of a case. Oral Surg Oral Med Oral Pathos 35 (4): 521–525

    Article  CAS  Google Scholar 

  15. Mairano E, Favia G, Ricco R (1996) Sialadenoma papilliferum: an immunohistochemical study of five cases. J Oral Pathol Med 25 (6): 336–342

    Article  PubMed  Google Scholar 

  16. Makek MS, Sailer HF (1985) Sialadenoma papilliferum. Schweiz Monatsschr Zahnmed 95 (6): 477–481

    PubMed  CAS  Google Scholar 

  17. Markopoulos A, Kayavis I, Papanayotou P (1997) Sialadenoma papilliferum of the oral cavity: report of a case an literature review. J Oral Maxillofac Surg 55 (10): 1181–1184

    Article  PubMed  CAS  Google Scholar 

  18. Masi JD, Hoang KG, Sawyer R (1986) Sialadenoma papilliferum of the adenoids in a 2-year-old child. Arch Pathol Lab Med 110 (6): 558–560

    PubMed  CAS  Google Scholar 

  19. McCoy JM, Eckert EF (1980) Sialadenoma papilliferum. J Oral Surg 38 (9): 691–693

    PubMed  CAS  Google Scholar 

  20. Mitre BK (1986) Sialadenoma papilliferum: report of case and review of literature. J Oral Maxillofac Surg 44 (6): 469–474

    Article  PubMed  CAS  Google Scholar 

  21. Nakahata A, Deguchi H, Yanagawa T et al. (1990) Coexpression of intermediate-sized filaments in sialadenoma papilliferum and other salivary gland neoplasms. J Oral Pathol Med 19: 313–318

    Article  PubMed  CAS  Google Scholar 

  22. Nasu M, Tagaki M, Ishikawa G (1981) Sialadenoma papilliferum: report of case. J Oral Surg 39 (5): 367–369

    PubMed  CAS  Google Scholar 

  23. Papanicolaou SJ, Triantafyllou AG (1987) Sialadenoma papilliferum of the oral cavity: a case report and review of the literature. J Oral Med 42 (1): 57–60

    PubMed  CAS  Google Scholar 

  24. Pimentel MT, Lopez Amando M, Garcia Sarandeses A (1995) Recurrent sialadenoma papilliferum of the buccal mucosa. J Laryngol Otol 109 (8): 787–790

    Article  PubMed  CAS  Google Scholar 

  25. Puts JJ, Voorsmit RA, van Haelst UJ (1984) Sialadenoma papilliferum of the palate. J Maxillofac Surg 12 (2): 90–94

    Article  PubMed  CAS  Google Scholar 

  26. Regezi JA, Lloyd RV, Zarbo RJ et al. (1985) Minor salivary gland tumors. A histologic and immunohistochemical study. Cancer 55: 108

    Article  PubMed  CAS  Google Scholar 

  27. Rennie JS, MacDonald DG, Critchlow HA (1984) Sialadenoma papilliferum. A case report and review of the literature. Int J Oral Surg 13 (5): 452–454

    Article  PubMed  CAS  Google Scholar 

  28. Rouse RV, Soetikno RM, Baker RJ et al. (1995) Esophageal submucosal gland duct adenoma. Am J Surg Pathol 19(10): 1191–6

    PubMed  CAS  Google Scholar 

  29. Seifert G, Bull HG, Donath K (1980) Histologic subclassification of the cystadenolymphoma of the parotid gland. Analysis of 275 cases. Virchows Arch A Pathol Anat Histol 388 (1): 13–38

    Article  PubMed  CAS  Google Scholar 

  30. Shirasuna K, Watatani K, Miyazaki T (1984) Ultrastructure of a sialadenoma papilliferum. Cancer 53 (3): 468–474

    Article  PubMed  CAS  Google Scholar 

  31. Solomon MP, Rosen Y, Alfonso A (1978) Intraoral papillary squamous cell tumors of the soft palate with features of sialadenoma papilliferum. Cancer 42: 1858

    Article  Google Scholar 

  32. Su JM, Hsu HK, Hsu PI, Wang CY, Chang HC (1998) Sialadenoma papilliferum of the esophagus. Am J Gastroenterol 93(3): 461–2

    Article  PubMed  CAS  Google Scholar 

  33. van der Wal JE, van der Waal I (1992) The rare sialadenoma papilliferum. Report of a case and review of the literature. Int J Oral Maxillofac Surg 21 (2): 104–106

    Article  PubMed  Google Scholar 

  34. Waldron CA, El-Mofty SK, Gnepp DR (1986) Tumors of the intraoral minor salivary glands: a demographic and histologic study of 426 cases. Oral surgery, Oral Medicine, Oral Pathology 66: 323–333

    Google Scholar 

  35. Wertheimer FW, Bonk K, Ruskin WJ (1983) Sialadenoma papilliferum. Int J Oral Surg 12: 190

    Article  PubMed  CAS  Google Scholar 

  36. Whittaker JS, Turner EP (1976) Papillary tumors of the minor salivary glands. J Clin Pathol 29: 795

    Article  PubMed  CAS  Google Scholar 

Download references

Interessenkonflikt

Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Wirz.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wirz, C., Bücheler, M., Neid, M. et al. Das seltene Sialadenoma papilliferum am harten Gaumen. HNO 55, 475–480 (2007). https://doi.org/10.1007/s00106-006-1403-x

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00106-006-1403-x

Schlüsselwörter

Keywords

Navigation