Kalziumpyrophosphat-Arthropathie des Kiefergelenks

Zusammenfassung

Eine Beteiligung des Kiefergelenks im Rahmen von Kristallarthropathien ist selten. Klinisch und radiologisch ist die Abgrenzung dieser Erkrankung insbesondere gegen maligne Tumoren der Glandula parotis und des Kiefergelenks ebenso schwierig wie bedeutsam. Der Kalziumpyrophosphat-Arthropathie liegt eine Überproduktion von anorganischem Pyrophosphat mit Ablagerung von Kristallen im Gelenk zugrunde. Insbesondere bei Erkrankung des Kiefergelenks kommt es durch Ablagerung der Kristalle im umgebenden Weichteilgewebe zur Ausbildung von Pseudotumoren. Anhand der Darstellung eines ungewöhnlich ausgedehnten Falles einer Kalziumpyrophosphat-Arthropathie des Kiefergelenks mit Ausbildung eines Pseudotumors wird daher im Rahmen einer Literaturübersicht auf die wesentlichen klinischen, ätiologischen, diagnostischen und therapeutischen Aspekte der Erkrankung eingegangen. Aktuelle Forschungsergebnisse zu Ätiologie und Pathogenese der Erkrankung werden referiert.

Abstract

Calcium pyrophosphate dihydrate deposition disease (CPPD) of the temporomandibular joint is rare. The disorder is characterized by the presence of crystal deposits within the affected joint. The deposition of crystals in adjacent soft tissue may lead to the formation of pseudotumors. This form of the disease is called tophaceous pseudogout and typically affects the temporomandibular joint. It is difficult to differentiate the disease, particularly from malignant tumors, on the clinical and radiographic findings alone. The diagnosis is based on histological identification of the calcium pyrophosphate crystals. We present an unusually advanced case of tophaceous pseudogout of the temporomandibular joint. The etiology, clinical and diagnostic criteria as well as treatment options are discussed on the basis of our own experience and a review of the literature.

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Correspondence to A. Koitschev.

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Koitschev, C., Kaiserling, E. & Koitschev, A. Kalziumpyrophosphat-Arthropathie des Kiefergelenks. HNO 51, 649–653 (2003). https://doi.org/10.1007/s00106-002-0744-3

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Schlüsselwörter

  • Kalziumpyrophosphatarthropathie
  • Pseudogicht
  • Kiefergelenk
  • Kristallarthropathie

Keywords

  • Calcium pyrophosphate dihydrate deposition disease
  • Pseudogout
  • Crystal deposition disease
  • Temporomandibular joint