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Some like it hot!

Oder: Was hat der Nobelpreis für Medizin mit Pruritus zu tun?

Some like it hot!

Or: what does the Nobel Prize for Medicine have to do with pruritus?

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Literatur

  1. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389(6653):816–824

    Article  CAS  Google Scholar 

  2. Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A (2010) Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science 330(6000):55–60

    Article  CAS  Google Scholar 

  3. McKemy DD, Neuhausser WM, Julius D (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416:52–58

    Article  CAS  Google Scholar 

  4. Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A (2002) A TRP channel that senses cold stimuli and menthol. Cell 108:705–715

    Article  CAS  Google Scholar 

  5. Caterina MJ, Pang Z (2016) TRP Channels in Skin Biology and Pathophysiology. Pharmaceuticals 9(4):77

    Article  Google Scholar 

  6. Inoue K, Koizumi S, Fuziwara S, Denda S, Inoue K, Denda M (2002) Functional vanilloid receptors in cultured normal human epidermal keratinocytes. Biochem Biophys Res Commun 291:124–129

    Article  CAS  Google Scholar 

  7. Ständer S, Moormann C, Schumacher M, Buddenkotte J, Artuc M, Shpacovitch V, Brzoska T, Lippert U, Henz BM, Luger TA, Metze D, Steinhoff M (2004) Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 13(3):129–139

    Article  Google Scholar 

  8. Cevikbas F, Lerner EA (2020) Physiology and pathophysiology of itch. Physiol Rev 100(3):945–982

    Article  Google Scholar 

  9. Feng J, Luo J, Yang P, Du J, Kim BS, Hu H (2018) Piezo2 channel-Merkel cell signaling modulates the conversion of touch to itch. Science 360(6388):530–533

    Article  CAS  Google Scholar 

  10. Agelopoulos et al (2022) Neurobiologie von Pruritus: Neue Konzepte. Hautarzt. https://doi.org/10.1007/s00105-022-05017-1

    Article  Google Scholar 

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Authors and Affiliations

  1. Kompetenzzentrum Chronischer Pruritus, Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland

    Sonja Ständer

  2. Universitätshautklinik, Universitätsklinikum Magdeburg, Magdeburg, Deutschland

    Evelyn Gaffal

Authors
  1. Sonja Ständer
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  2. Evelyn Gaffal
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Correspondence to Sonja Ständer.

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S. Ständer und E. Gaffal geben an, dass kein Interessenkonflikt besteht.

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Ständer, S., Gaffal, E. Some like it hot!. Dermatologie 73, 625–626 (2022). https://doi.org/10.1007/s00105-022-05022-4

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  • DOI: https://doi.org/10.1007/s00105-022-05022-4

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