Zusammenfassung
Hidradenitis suppurativa (HS)/Acne inversa (AI) geht mit zahlreichen und relevanten Einschränkungen der Lebensqualität für die Betroffenen und ihre Angehörigen einher. Literaturangaben zur Prävalenz der HS variieren erheblich, sie ist jedoch wahrscheinlich höher als in früheren Publikationen angenommen. Die Versorgung der HS geht mit hohen Kosten für das Gesundheitssystem und die Betroffenen einher. Die Einführung der Biologikatherapie hat zu weiteren Kosten, jedoch auch erheblichem Mehrnutzen in der Versorgung geführt. Angesichts der Komplexität von Diagnostik und Therapie besteht ein besonderer Bedarf an optimierten Versorgungskonzepten, um die Last für die Betroffenen, ihre Angehörigen und das Gesundheitssystem zu reduzieren.
Abstract
Hidradenitis suppurativa/acne inversa (HS) is associated with numerous and relevant restrictions on the quality of life for those affected and their relatives. The exact prevalence of HS varies significantly across studies, but it is likely to be higher than suggested in previous publications. HS care is associated with high costs for the healthcare system and for those affected. The introduction of biologic therapy has led to additional costs, but also to considerable additional benefits in terms of care. In view of the complexity of diagnostics and therapy, there is a particular need for optimized care concepts in order to reduce the burden on those affected, their relatives and the healthcare system.
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Danksagung
Die Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Würzburg, und die Hochschulklinik für Dermatologie, Venerologie und Allergologie, Immunologisches Zentrum, Städtisches Klinikum Dessau, sind Gesundheitszentren des Europäischen Referenz-Netzwerkes für Seltene und Schwere Hautkrankheiten (ERN Skin, ALLOCATE Skin-Gruppe).
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Interessenkonflikt
V. Frings und G.D. Nikolakis geben an, dass kein Interessenkonflikt besteht. D. Presser und M. Goebeler waren Prüfarzte in klinischen Studien zur AI/HS der Firmen UCB und Novartis. C.C. Zouboulis hat Berater- und Vortragshonorare von Idorsia, Incyte, InflaRx, Janssen, Novartis, Regeneron und UCB erhalten, die nicht mit diesem Manuskript in Verbindung stehen. Seine Abteilung erhielt Honorare von AbbVie, InflaRx, Novartis und UCB für seine Teilnahme an klinischen Studien. N. Kirsten hat Berater- und Vortragshonorare von AbbVie, Eli Lilly, Janssen, Novartis, UCB, Streamedup, Uluru erhalten und war als Prüfärztin an klinischen Studien zur AI/HS der Firmen UCB, AbbVie, Novartis beteiligt. M. Augustin hat Berater- und Vortragshonorare von AbbVie, Almirall, Amgen, Biogen, Boehringer Ingelheim, Celgene, Centocor, Eli Lilly, GSK, Janssen-Cilag, LEO, Medac, Merck, MSD, Novartis, Pfizer, UCB und XenoPort erhalten und war an klinischen Studien der Firmen AbbVie, Novartis, UCB zur AI/HS als Prüfarzt beteiligt.
Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.
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Die Autoren N. Kirsten und V. Frings haben zu gleichen Teilen als Erstautorinnen zum Manuskript beigetragen.
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Kirsten, N., Frings, V., Nikolakis, G.D. et al. Epidemiologie, Patientenlebensqualität und Behandlungskosten der Hidradenitis suppurativa/Acne inversa. Hautarzt 72, 651–657 (2021). https://doi.org/10.1007/s00105-021-04851-z
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DOI: https://doi.org/10.1007/s00105-021-04851-z