Psychiatrische Komorbidität bei Hidradenitis suppurativa/Acne inversa

Psychiatric comorbidities in hidradenitis suppurativa/acne inversa

Zusammenfassung

Hintergrund

Die Befunde der vereinzelten durchgeführten Studien legen nahe, dass v. a. Depressionen und Angststörungen als häufigste psychiatrische Komorbiditäten bei Patienten mit einer Hidradenitis suppurativa/Acne inversa (HS/AI) vorkommen.

Methodik

Im Rahmen einer prospektiven Studie wurden 51 Patienten mit einer HS/AI hinsichtlich einer psychiatrischen Komorbidität mittels eines standardisierten Interviews und Fragebögen näher untersucht.

Ergebnisse

Bei der fachpsychiatrischen Untersuchung fand sich bei 29,4 % der HS/AI-Patienten eine zusätzliche psychische Symptomatik, die sich v. a. in Form einer depressiven Störung manifestierte. Die HS/AI-Patienten waren eher jung, eher Frauen und wiesen ein häufiges Vorkommen von Nikotin- und Alkoholkonsum und eine positive Familienanamnese für eine paternale Alkoholabhängigkeit auf. Darüber hinaus bestanden bei den HS/AI-Patienten deutlicher psychosoziale Einschränkungen in Form von fehlender Partnerschaft und eine durch die vorhandenen Symptome deutliche psychische Belastung.

Schlussfolgerung

Die Acne inversa ist eine schwere chronische entzündliche Hauterkrankung, die ähnlich wie andere inflammatorische Dermatosen mit psychischer Komorbidität und psychosozialen Beeinträchtigungen einhergeht. Da v. a. junge Patienten betroffenen sind, sollte frühzeitig eine psychiatrisch-psychotherapeutische Mitbehandlung erwogen werden.

Abstract

Background

The findings of most studies suggest that depression and anxiety disorders are the most common psychiatric comorbidities in patients with hidradenitis suppurativa/acne inversa (HS/AI).

Methods

In a prospective study, 51 patients with HS/AI were further examined for psychiatric comorbidity using a standardized interview and questionnaires.

Results

In psychiatric examination, 29.4% of HS/AI patients had additional mental symptoms, mainly manifested as depressive disorder. The HS/AI patients were rather young and female, and they showed a high incidence of nicotine and alcohol use, and a positive family history of paternal alcohol dependence. In addition, HS/AI patients experienced more severe psychosocial impairments in the form of lack of partnership and lower school attainment.

Conclusions

Acne inversa is a severe chronic inflammatory skin disease that, like other inflammatory dermatoses, is associated with mental comorbidity and psychosocial impairments. Since especially young patients are affected, a psychiatric–psychotherapeutic cotreatment should be considered already at an early stage.

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Correspondence to Professor Dr. med. Georg Juckel.

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Interessenkonflikt

P. Mavrogiorgou, G. Juckel, A. Reimelt, S. Hessam, L. Scholl, J.L. Frajkur, E. Stockfleth und F.G. Bechara geben an, dass kein Interessenkonflikt besteht.

Alle beschriebenen Untersuchungen am Menschen oder an menschlichem Gewebe wurden mit Zustimmung der zuständigen Ethikkommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.

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Mavrogiorgou, P., Juckel, G., Reimelt, A. et al. Psychiatrische Komorbidität bei Hidradenitis suppurativa/Acne inversa. Hautarzt (2021). https://doi.org/10.1007/s00105-020-04742-9

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Schlüsselwörter

  • Psychische Störungen
  • Depression
  • Angststörungen
  • Chronische entzündliche Hauterkrankung
  • Psychosoziale Beeinträchtigung

Keywords

  • Mental disorders
  • Depression
  • Anxiety disorders
  • Chronic inflammatory diseases of the skin
  • Psychosocial impairment