Zusammenfassung
Narben entstehen nach tiefdermalen Verletzungen der Haut und können sich in Abhängigkeit von Alter, Lokalisation, Ursache, Heilungsverlauf und individueller Disposition als unreife, reife, atrophe, hypertrophe oder keloidale Narben präsentieren. Vor allem Keloide und hypertrophe Narben sind häufig mit Juckreiz, Spannungsgefühl, Schmerzen und sogar Funktionseinschränkungen assoziiert und können die Lebensqualität von Patienten signifikant reduzieren. Auch vermeintlich physiologische Narbentypen, wie beispielsweise Ritznarben nach Selbstverletzungen, führen in vielen Fällen zu einem ausgeprägten Leidensdruck bei Betroffenen. Trotz intensiver Forschungsaktivität sind insbesondere die Pathomechanismen der überschießenden Narbenbildung bisher nur unzureichend verstanden und sicher wirksame Behandlungsmöglichkeiten bisher nicht verfügbar. Aufgrund zunehmend soliderer Studienlage werden heutzutage neben etablierten, konventionellen Verfahren vermehrt verschiedene Lasertechnologien und -wellenlängen zur Behandlung von verschiedenen Narbentypen eingesetzt.
Abstract
Scar formation is the consequence of trauma to the skin that affects the deep parts of the dermis. Different scar types like immature, mature, atrophic, hypertrophic, or keloid scars can develop depending on factors like age, anatomic localization, cause of trauma, the course of the healing process, and individual predispositions. Keloids and hypertrophic scars are often associated with itching, pain, tautness of the skin, and functional impairments, thus, leading to significantly reduced quality of life in some patients. However, even seemingly physiologically healed scars can cause tremendous psychological strain as is the case with self-harm scars. Despite increased research efforts, the exact pathomechanisms of excessive scarring are still scarcely understood, and dependably effective treatment options are often lacking. However, through continually improving scientific progress, scar treatment paradigms for a variety of scar types, thus far often dominated by conventional treatment methods, are increasingly complemented by new laser technologies and wavelengths.
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G.G. Gauglitz ist als Referent und Berater für Merz Pharmaceuticals, Sinclair Pharma, Galderma, Lumenis, Candela, Asclepion, Cynosure, Pollogen, Johnson&Johnson, Almiral, Biofrontera, Urgo GmbH, Mi.To.Pharm, Classys und MediWound tätig. M.T. Clementoni ist als Referent und Berater für Lumenis tätig. J. Pötschke gibt an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben. Im Falle von nicht mündigen Patienten liegt die Einwilligung eines Erziehungsberechtigten oder des gesetzlich bestellten Betreuers vor.
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Gauglitz, G.G., Pötschke, J. & Clementoni, M.T. Laser und Narben. Hautarzt 69, 17–26 (2018). https://doi.org/10.1007/s00105-017-4072-7
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DOI: https://doi.org/10.1007/s00105-017-4072-7