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Prinzipien der Steroidtherapie

Principles of glucocorticoid therapy

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Zusammenfassung

Die Prinzipien einer systemischen Glukokortikoidtherapie bei dermatologischen Indikationen werden in einem Überblick zusammengefasst. Um Glukokortikoide effektiv und nebenwirkungsarm einsetzen zu können, werden Pharmakologie, endogene Regulation und Wirkmechanismen sowie Nebenwirkungen und ihr Management vorgestellt. Moderne Therapieschemata wie die zirkadiane Anwendung und die Low-dose-Therapie werden ebenso besprochen wie Absetzungsmanöver und die wichtigsten Indikationen für Glukokortikoide in der Dermatologie.

Abstract

The principles of systemic glucocorticoid (GC) therapy in dermatology are reviewed. As a basis for an efficient GC therapy with few side effects the pharmacology, endogenous regulation as well as the mechanisms and side effects of GCs as well as their management are introduced. Modern therapeutic approaches such as circadian application and low-dose therapy are discussed as well as principles of tapering dosages and the most important indications for systemic GCs in dermatology.

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  1. Klinik für Hautkrankheiten – Allgemeine Dermatologie und Venerologie, Universitätsklinikum Münster, Von-Esmarch Str. 58, 48149, Münster, Deutschland

    J. Ehrchen

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  1. J. Ehrchen
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Correspondence to J. Ehrchen.

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Ehrchen, J. Prinzipien der Steroidtherapie. Hautarzt 63, 973–984 (2012). https://doi.org/10.1007/s00105-012-2471-3

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  • DOI: https://doi.org/10.1007/s00105-012-2471-3

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