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Erythema anulare centrifugum

Ein klinisches Reaktionsmuster

Erythema annulare centrifugum

A clinical reaction pattern

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Zusammenfassung

Das Erythema anulare centrifugum (EAC) repräsentiert ein klinisches Reaktionsmuster und ist keine spezifische klinisch-histologische Entität. Die klinische und histologische Differenzialdiagnose EAC sollte wenigstens 3 Hauptgruppen an Erkrankungen in Erwägung ziehen, die sich häufig hinter diesem Begriff verbergen: ein (tumider) Lupus erythematodes, spongiotische Dermatitiden und Pseudolymphome.

Abstract

Erythema annulare centrifugum (EAC) is a clinical reaction pattern and not a specific clinicohistologic entity. The clinical and histologic differential diagnosis of EAC should take at least three main disease groups into consideration, which are often classified under this disorder: (tumid) lupus erythematosus, spongiotic dermatitides, and pseudolymphomas.

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Abbreviations

B. burgdorferi:

Borrelia burgdorferi

EAC:

Erythema anulare centrifugum

FFM:

„focus-floating microscopy“

HE:

Hämatoxylin-Eosin

LE:

Lupus erythematodes

LIS:

„lymphocytic infiltration of the skin Jessner-Kanof“

PCR:

Polymerasekettenreaktion

PR:

Pityriasis rosea

Literatur

  1. Wolff K, Goldsmith LA, Katz SI et al (2008) Erythema anulare centrifugum and other figurate erythemas. Fitzpatrick’s dermatology in general medicine, 7. Auf. McGraw-Hill, S 366–368

  2. Fritsch P (2004) Figurierte Erytheme. Dermatologie Venerologie, 2. Aufl. Springer, Berlin Heidelberg New York Tokyo, S 218–219

  3. Darier J (1916) De l’érythème anulaire centrifuge. (érythème papulo-circiné migrateur et chronique) et de quelques eruptions analogues. Ann Dermatol Syphiligr 6:57–76

    Google Scholar 

  4. Weyers W (2003) Erythema anulare centrifugum. In: Kerl H, Garbe C, Cerroni L (Hrsg) Histopathologie der Haut. Springer, Berlin Heidelberg New York Tokyo, S 108–110

  5. Ackerman AB (1995) Erythema anulare centrifugum. Diagnosis of inflammatory skin diseases, 2. Aufl. Williams & Wilkins, Baltimore, S 623–630

  6. Kim KJ, Chang SE, Choi JH et al (2002) Clinicopathologic analysis of 66 cases of erythema anulare centrifugum. J Dermatol 29:61–67

    PubMed  Google Scholar 

  7. Weyers W, Diaz-Cascajo C, Weyers I (2003) Erythema anulare centrifugum: results of a clinicopathologic study of 73 patients. Am J Dermatopathol 25:451–462

    Article  PubMed  Google Scholar 

  8. Ziemer M, Eisendle K, Zelger B (2009) New concepts on erythema anulare centrifugum: a clinical reaction pattern that does not represent a specific clinicopathological entity. Br J Dermatol 160:119–126

    Article  CAS  PubMed  Google Scholar 

  9. Ziemer M, Eisendle K, Muller H, Zelger B (2009) Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma. Br J Dermatol 161:583–590

    Article  CAS  PubMed  Google Scholar 

  10. Toonstra J, Wildschut A, Boer J et al (1989) Jessner’s lymphocytic infiltration of the skin. A clinical study of 100 patients. Arch Dermatol 125:1525–1530

    Article  CAS  PubMed  Google Scholar 

  11. Abele DC, Anders KH, Chandler FW (1989) Benign lymphocytic infiltration (Jessner-Kanof): another manifestation of borreliosis? J Am Acad Dermatol 21:795–797

    Article  CAS  PubMed  Google Scholar 

  12. Stechenberg BW (1988) Lyme disease: the latest great imitator. Pediatr Infect Dis J 7:402–409

    Article  CAS  PubMed  Google Scholar 

  13. Asbrink E, Hovmark A (1987) Cutaneous manifestations in Ixodes-borne Borrelia spirochetosis. Int J Dermatol 26:215–223

    Article  CAS  PubMed  Google Scholar 

  14. Eisendle K, Grabner T, Zelger B (2007) Morphoea: a manifestation of infection with Borrelia species? Br J Dermatol 157:1189–1198

    Article  CAS  PubMed  Google Scholar 

  15. Tuffanelli D (1987) Do some patients with morphea and lichen sclerosis et atrophicans have a Borrelia infection? Am J Dermatopathol 9:371–373

    Article  CAS  PubMed  Google Scholar 

  16. Eisendle K, Baltaci M, Kutzner H, Zelger B (2008) Detection of spirochaetal microorganisms by focus floating microscopy in necrobiosis lipoidica in patients from central Europe. Histopathology 52:877–884

    Article  CAS  PubMed  Google Scholar 

  17. Zelger B, Eisendle K, Mensing C (2007) Detection of spirochetal micro-organisms by focus-floating microscopy in necrobiotic xanthogranuloma. J Am Acad Dermatol 57:1026–1030

    Article  PubMed  Google Scholar 

  18. Kaatz M, Zelger B, Norgauer J, Ziemer M (2007) Lymphocytic infiltration (Jessner-Kanof): lupus erythematosus tumidus or a manifestation of borreliosis? Br J Dermatol 157:403–405

    Article  CAS  PubMed  Google Scholar 

  19. Fischer JR, LeBlanc KT, Leong JM (2006) Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans. Infect Immun 74:435–441

    Article  CAS  PubMed  Google Scholar 

  20. Parveen N, Caimano M, Radolf JD, Leong JM (2003) Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell binding. Mol Microbiol 47:1433–1444

    Article  CAS  PubMed  Google Scholar 

  21. Eisendle K, Grabner T, Zelger B (2007) Focus floating microscopy: „gold standard“ for cutaneous borreliosis? Am J Clin Pathol 127:213–222

    Article  CAS  PubMed  Google Scholar 

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Correspondence to M. Ziemer MD.

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Ziemer, M., Eisendle, K. & Zelger, B. Erythema anulare centrifugum. Hautarzt 61, 967–972 (2010). https://doi.org/10.1007/s00105-010-1976-x

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