Zusammenfassung
Soforttypsensibilisierung gegen Lipid-Transfer-Proteine (LTPs) führen insbesondere in Mittelmeerländern zu schweren anaphylaktischen Reaktionen nach Verzehr verschiedener pflanzlicher Nahrungsmittel. Durch komponentenbasierte Diagnostik konnte das Pfirsich-LTP Pru p 3 als Markerallergen identifiziert werden. Wir präsentieren den Fall einer 30-jährigen Patientin aus Spanien mit einer Soforttypsensibilisierung gegen LTPs, die unter anderem nach Verzehr von Äpfeln, Weintrauben und Blumenkohl jeweils schwere anaphylaktische Reaktionen entwickelte und bei der ein Nachweis von spezifischem IgE gegen das rekombinante Pru p 3 die Diagnose sicherte.
Abstract
Sensitization to lipid transfer proteins (LTPs), a pan-allergen in plants, causes severe anaphylactic reactions to foods, especially in the Mediterranean area. A component-based diagnostic approach identified the peach LTP Pru p 3 as a major allergen. We present the case of a 30-year-old LTP-sensitized Spanish woman with a history of severe anaphylactic reaction to grapes, apple and cauliflower in which the detection of specific IgE against the recombinant protein Pru p 3 led to the diagnosis.
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Brans, R., Merk, H. Komponentenbasierte Diagnostik. Hautarzt 61, 382–385 (2010). https://doi.org/10.1007/s00105-010-1955-2
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DOI: https://doi.org/10.1007/s00105-010-1955-2