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Pruritus bei Urtikaria

Pruritus and urticaria

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Zusammenfassung

Die Urtikaria repräsentiert eine der häufigsten dermatologischen Erkrankungen, die durch das transiente Auftreten von juckenden Urtikae charakterisiert wird. Die Empfindung des Pruritus wird von Patienten mit chronischer Urtikaria als kribbelnd, brennend oder stechend angegeben. Da die Pruritusattacken und das Auftreten von Urtikae nicht vorhersehbar sind, beeinflusst die Urtikaria die Lebensqualität der Patienten stark. In diesem Überblick fokussieren wir uns auf die klinischen Charakteristika, therapeutischen Optionen sowie neue pathophysiologische Mechanismen wie das T-Zell-Zytokin IL-31 beim Pruritus von Patienten mit chronischer Urtikaria.

Abstract

Urticaria is a frequent dermatological skin disease characterized by the occurrence of transient pruritic wheals. The sensation of pruritus has been described to be stinging, tickling and burning in patients with chronic urticaria. Because of the unpredictable attacks of pruritus and swelling, urticaria strongly affects the quality of life in patients. In this review we focus on clinical characteristics, therapeutic options and new pathophysiological mechanisms including the novel T-cell cytokine IL-31 in pruritus of patients with chronic urticaria.

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Authors and Affiliations

  1. Klinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover, Ricklinger Str. 5, 30449, Hannover, Deutschland

    U. Raap, A. Kapp & B. Wedi

  2. Klinik und Poliklinik für Hautkrankheiten, Universitätsklinikum Münster, Münster, Deutschland

    S. Ständer

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  1. U. Raap
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  2. A. Kapp
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  4. S. Ständer
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Correspondence to U. Raap.

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Raap, U., Kapp, A., Wedi, B. et al. Pruritus bei Urtikaria. Hautarzt 61, 737–742 (2010). https://doi.org/10.1007/s00105-010-1931-x

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  • DOI: https://doi.org/10.1007/s00105-010-1931-x

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