Schwere Soforttypallergie nach Verzehr roher Paprika

Severe type 1-allergy to raw bell pepper

Zusammenfassung

Wir berichten über einen Patienten mit einer selten auftretenden anaphylaktischen Reaktion nach dem Verzehr roher Paprika. Die allergologische Diagnostik zeigte ein komplexes Sensibilisierungsmuster, u. a. auf Gräser und Birke mit Hinweisen auf eine pollenassoziierte Nahrungsmittelallergie. Am ehesten führen wir die Reaktion auf eine Bet-v-1-bedingte Kreuzreaktion zurück. Im Westernblot zeigte sich eine Bindung des Patientenserums an ein 11-kDa-Protein, bei dem es sich möglicherweise um ein bisher unbekanntes Allergen der Paprikapflanze handelt oder um ein Fragment des Bet-v-1-homologen Paprikaproteins.

Abstract

We report on a patient with rare anaphylaxis after ingestion of raw bell pepper. A complex cluster of sensitization including grass and birch pointed out a possible pollen-associated food allergy. We suggest that the severe reaction is due to cross-reactivity towards Bet v 1. Western blot showed binding of the patient’s serum to an 11 kDa protein, which has not been described yet and might be a new allergenic structure of the bell pepper plant or a fragment of the Bet v 1-homologous bell pepper protein.

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Correspondence to Dr. R.D. Rüger.

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Rüger, R., Wagner, S., Simon, J. et al. Schwere Soforttypallergie nach Verzehr roher Paprika. Hautarzt 61, 339–342 (2010). https://doi.org/10.1007/s00105-009-1776-3

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Schlüsselwörter

  • Paprika
  • Anaphylaxie
  • Nahrungsmittelallergie
  • Bet v 1
  • 11-kDa-Protein

Keywords

  • Bell pepper
  • Anaphylaxis
  • Food allergy
  • Bet v 1
  • 11 kDa protein