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Therapie berufsbedingter Hauterkrankungen

Therapy of occupational skin diseases

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Zusammenfassung

Handekzeme zählen zu den häufigsten Hauterkrankungen. Etwa 5–10% der Bevölkerung leiden an einem chronischen Handekzem. In der Liste der gemeldeten Berufserkrankungen nehmen Handekzeme eine führende Position (>90% aller beruflichen Hauterkrankungen) ein. Die Therapie des Handekzems verursacht hohe Kosten und ist oft mit einer eingeschränkten Lebensqualität verbunden. Die Therapie ist komplex, nicht immer erfolgreich und führt im ungünstigsten Fall zur Berufsaufgabe. Der vorliegende Beitrag gibt einen aktuellen Überblick zu dem Spektrum therapeutischer Möglichkeiten bei berufsbedingtem Handekzem.

Abstract

Hand eczema is one of the most frequent skin diseases. About 5-10% of population has chronic hand eczema. In addition, hand eczema accounts for more than 90% of occupational skin diseases. The therapy of hand eczema is expensive and often leads to a loss in quality of life. The therapy is complex, not always successful and can lead in the worst case to the patient being forced to give up or change their profession. We review the therapeutic options to treat occupational hand eczema.

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Literatur

  1. Bayerl C, Garbea A et al (1999) Pilotstudie zur Therapie des beruflich bedingten Handekzems mit einer neuen tragbaren UVB-Bestrahlungseinheit. Akt Derm 25:302–305

    Google Scholar 

  2. Bleeker J, Anagrius C et al (1989) Double-blind comparative study of Cortecoderm cream + unguentum Merck and Betnovate cream + unguentum Merck in hand dernatitis. J Dermatolog Treat 1:87–90

    Article  Google Scholar 

  3. Brasch J, Becker D et al (2007) Contact dermatitis. J Dtsch Dermatol Ges 5:943–951

    Article  PubMed  Google Scholar 

  4. Dickel H, Bruckner T et al (2002) Surveillance scheme for occupational skin disease in the Saarland, FRG: first report from BKH-S. Contact Dermatitis 46:197–206

    Article  CAS  PubMed  Google Scholar 

  5. Diepgen TL, Coenraads PJ (1999) The epidemiology of occupational contact dermatitis. Int Arch Occup Environ Health 72:496–506

    Article  CAS  PubMed  Google Scholar 

  6. Diepgen TL, Elsner P, Schliemann S et al (2009) Leitlinie Management von Handekzemen. J Dtsch Dermatol Ges 7 (Suppl 3):1–16

    Google Scholar 

  7. Diepgen TL, Schmidt A (2002) Werden Inzidenz und Prävalenz berufsbedingter Hauterkrankungen unterschätzt? Arbeitsmed Sozialmed Umweltmed 37:477–480

    Google Scholar 

  8. Diepgen TL, Svensson A et al (2005) Therapie von Handekzemen. Was können wir von publizierten Studien lernen? Hautarzt 56:224–231

    Article  CAS  PubMed  Google Scholar 

  9. Funke UM, Fartasch M et al (2001) Incidence of work-related hand eczema during apprenticeship: first result of a prospektive cohort study in the car industry. Contact Dermatitis 44:166–172

    Article  CAS  PubMed  Google Scholar 

  10. Grattan CEH, Carmichael AJ et al (1991) Comparison of topical PUVA with UVA for chronic vesicular hand eczema. Acta Derm Venereol 71:118–122

    CAS  PubMed  Google Scholar 

  11. Gupta AK, Shear NH et al (1993) Betamethasone dipropionate polyacrylic filmforming lotion in the treatment of handdermatitis. Int J Dermatol 32:828–829

    Article  CAS  PubMed  Google Scholar 

  12. Hölzle E, Gollnick H et al (2007) S1-Leitlinie Empfehlungen zur Phototherapie und Photochemotherapie. http://www.uni-duesseldorf.de/AWMF/II/013–029.htm

  13. Hölzle E, Reinauer S et al (2004) Empfehlungen zur Leitungswasser-Iontophorese. J Dtsch Dermatol Ges 11:956–962

    Google Scholar 

  14. Krutmann J, Medve-Koenigs K et al (2005) Ultravioletfree phototherapy. Photodermatol Photoimmunol Photomed 21:59–61

    Article  PubMed  Google Scholar 

  15. Lugner TA, Elsner P et al (2005) S1-Leitlinie Topische Dermatotherapie mit Glukokortikoiden – Therapeutischer Index. http://www.uni-duesseldorf.de/ AWMF/II/013–034.htm

  16. Meding B (2004) Incidence of hand eczema – a population-based study. J Invest Dermatol 122:873–877

    Article  CAS  PubMed  Google Scholar 

  17. Moller H, Svartholm H et al (1983) Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetate. Curr Med Res Opin 8:640–644

    CAS  PubMed  Google Scholar 

  18. Mrowietz U, Czech W (2006) S1-Leitlinie Therapie mit Ciclosporin in der Dermatologie. http://www.uni-duesseldorf.de/AWMF/II-na/013–013.htm

  19. Polderman MCA, Govaert JCM et al (2003) A double blind placebo-controlled trial of UVA-1 in treatment of dyshidrotic eczema. Clin Exp Dermatol 28:548–587

    Article  Google Scholar 

  20. Rosen K, Mobacken H et al (1987) Chronic eczematous dermatitis of the hands: a comparison of PUVA and UVB treatment. Acta Derm Venereol 67:48–54

    CAS  PubMed  Google Scholar 

  21. Ruzicka T, Larsen FG et al (2004) Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy. Results of a randomized, double-blind, placebo-controlled, multicenter trial. Arch Dermatol 140:1453–1459

    Article  CAS  PubMed  Google Scholar 

  22. Ruzicka T, Lynde CW (2008) Efficany and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial. Br J Dermatol 158:808–817

    Article  CAS  PubMed  Google Scholar 

  23. Schliemann S, Kelterer D et al (2008) Tacrolimus ointment in the treatment of occupationallyinduced chronic hand dermatitis. Contact Dermatitis 59:299–306

    Article  Google Scholar 

  24. Schmitt J, Schmitt N et al (2007) Cyclosporin in the treatment of patients with atopic eczema a systematic review and metaanalysis. J Eur Acad Dermatol Venereol 21:606–619

    CAS  PubMed  Google Scholar 

  25. Schöfer H, Brockmeyer N et al (2008) S1-Leitlinie Staphylokokkeninfektionen der Haut. http://www.uni-duesseldorf.de/AWMF/II013–038.htm

  26. Sheehan- Dare RA, Goodfield MJ et al (1989) Topical psoralen phototherapy (PUVA) and superficial radiotherapy in the treatment of chronic hand eczema. Br J Dermatol 121:65–69

    Article  Google Scholar 

  27. Sjovall P, Christensen OB (1987) Local and systemic effect of UVB irradiation in patients with chronic hand eczema. Acta Derm Venereol 67:538–541

    CAS  PubMed  Google Scholar 

  28. Soost S, Graupner I, Morch-Röder A et al (2007) 7-Schritte-Beratungsprogramm für hauterkrankte Beschäftigte im Gesundheitsdienst und Friseurwesen. J Dtsch Dermatol Ges 5:756–760

    Article  PubMed  Google Scholar 

  29. Tschachler E, Brockmeyer N et al (2008) S1-Leitlinie Streptokokkeninfektionen der Haut und Schleimhäute. http://www.uni-duesseldorf.de/AWMF/II/013–054.htm

  30. Uggeldahl PE, Kero M et al (1986) Comparative effects of desonide cream 01% and 005% in patients with hand eczema. Curr Ther Res 40:969–973

    Google Scholar 

  31. van Coervorden AM, Coenraads PJ et al (2004) Overwiew of studies of treatment for hand eczema- the EDEN hand eczema survey. Br J Dermatol 151:446–451

    Article  Google Scholar 

  32. van Coevorden AM, Kaaber K et al (2004) Comparison of oral psoralen- UV-A with a portable tanning unit at home vs hospital administered bath psoralen- UV-A in patients with chronic hand eczema. Arch Dermatol 140:1463–1466

    Article  Google Scholar 

  33. Veien NK, Kaaber K et al (1995) Longterm, intermittent, treatment of chronic hand eczema with mometasone furoate. Br J Dermatol 140:882–886

    Article  Google Scholar 

  34. Werfel T, Aberer W et al (2008) S2-Leitlinie Neurodermitis; http://www.uni-duesseldorf.de/AWMF/II/013–027.htm

  35. Wohlrab J, Jost G et al (2007) Antiseptic efficancy of low dosed topical triclosan/chlorhexidine combination therapy in atopic dermatitis. Skin Pharmacol Physiol 20:71–76

    Article  CAS  PubMed  Google Scholar 

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  1. Klinik für Dermatologie, Venerologie und Allergologie, Charité- Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland

    S. Soost &  M. Worm

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  1. S. Soost
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  2. M. Worm
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Soost, S., Worm, M. Therapie berufsbedingter Hauterkrankungen. Hautarzt 60, 718–721 (2009). https://doi.org/10.1007/s00105-008-1706-9

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