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Eruptive Xanthome bei Hypertriglyzeridämie

Eruptive xanthomas with hypertriglyceridemia

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Zusammenfassung

Eruptive Xanthome sind häufig kutane Symptome einer erhöhten Plasmakonzentration triglyzeridreicher Lipoproteine und können Indikator einer unentdeckten Fettstoffwechselstörung, eines Diabetes mellitus oder einer Pankreatitis sein. Wir berichten über eine 42-jährige Patientin mit akut aufgetretenen disseminierten eruptiven Xanthomen aufgrund einer ausgeprägten Hyperlipidämie sowie dekompensiertem Diabetes mellitus bei akuter Pankreatitis. Nach optimierter Blutzucker- und Fettstoffwechseleinstellung bildeten sich die Hautläsionen wieder zurück. Eruptive Xanthome sollten frühzeitig diagnostiziert werden und zur weiterführenden Differenzialdiagnostik einschließlich der Stoffwechselparameter führen.

Abstract

Eruptive xanthomas are often associated with elevated plasma levels of triglyceride-rich lipoproteins and may be a marker for occult hyperlipidemia, diabetes mellitus or pancreatitis. A 42-year-old woman presented with the acute onset of disseminated eruptive xanthomas secondary to hyperlipidemia associated with diabetes and concomitant acute pancreatitis. She improved after optimized insulin therapy and intensified treatment of hyperlipidemia. Eruptive xanthomas should be diagnosed early and lead to further metabolic evaluations.

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Authors and Affiliations

  1. Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig A.ö.R, Philipp-Rosenthal-Straße 23–25, 04103, Leipzig, Deutschland

    R. Renner, I. Teuwen, R. Treudler & J.C. Simon

  2. Klinik für Dermatologie und Venerologie, Vivantes Klinikum im Friedrichshain, Berlin, Deutschland

    W. Harth

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  1. R. Renner
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  2. I. Teuwen
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  3. W. Harth
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  4. R. Treudler
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  5. J.C. Simon
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Correspondence to R. Renner.

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Renner, R., Teuwen, I., Harth, W. et al. Eruptive Xanthome bei Hypertriglyzeridämie. Hautarzt 59, 995–999 (2008). https://doi.org/10.1007/s00105-008-1534-y

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  • DOI: https://doi.org/10.1007/s00105-008-1534-y

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