Skip to main content
Log in

Kutane Larva migrans

Cutaneous larva migrans

  • Leitthema
  • Published:
Der Hautarzt Aims and scope Submit manuscript

Zusammenfassung

Durch den zunehmenden Massentourismus mit immer preiswerteren und exotischeren Reisezielen gewinnen mitgebrachte Tropenerkrankungen eine wachsende Bedeutung in der dermatologischen Behandlung. Die kutane Larva-migrans-Infektion ist eines der häufigsten in den Tropen erworbenen „Reisesouvenirs“. Krankheitsauslösend ist eine Nematodeninfektion mit den Parasiten des Hunde- oder Katzenhakenwurmes (Ancylostoma braziliense oder A. caninum). Charakteristisch ist ein gyriertes, serpinginöses, ggf. auch vesikuläres Erythem, das nach Penetration des Parasiten in die Epidermis und der folgenden intraepidermalen Migration der Larven entsteht. Begleitend besteht im Bereich der betroffenen Haut oft starker Pruritus. Die Erkrankung ist meist an den durch Gehen bzw. Sitzen in Sand exponierten Bereichen der Füße, der Unterschenkel bzw. des Gesäßes zu finden. Die nach mehreren Wochen selbstlimitierende, jedoch subjektiv als äußerst unangenehm empfundene Erkrankung wird überwiegend lokal (z. B. durch Kryotherapie) behandelt. Die Prognose der Erkrankung ist exzellent, jedoch werden protrahierte bzw. komplizierte Verläufe z. B. durch Superinfektionen beobachtet.

Abstract

As a result of the rise of mass tourism with increasingly cheap and exotic destinations, tropical diseases are becoming an increasingly important part of dermatology. Infection with cutaneous larva migrans is one of the most common “souvenirs” from the tropics. The disease is caused by the nematode infection with dog or cat hookworm parasites (Ancylostoma braziliense or A. caninum). The characteristic manifestation is a gyrated, serpiginous and in some cases vesicular erythema, which appears after penetration of the epidermis by the parasite and the subsequent intraepidermal migration of the larva. This is often accompanied by intense pruritus in the affected skin. The infection is usually found in those areas of the foot, calf or buttocks exposed by walking or sitting on sand. Although subjectively very unpleasant, the disease is self-limiting and resolves after several weeks; it is treated locally in most cases (e.g. using cryotherapy). The prognosis of the disease is excellent, but a prolonged course or complications have been observed, e.g. due to superinfection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1

Literatur

  1. Blackwell V, Vega-Lopez F (2001) Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveler. Br J Dermatol 145: 434–437

    Article  PubMed  CAS  Google Scholar 

  2. Brenner MA, Patel MB (2003) Cutaneous larva migrans: the creeping eruption. Cutis 72: 111–115

    PubMed  Google Scholar 

  3. Caumes E, Carriere J, Datry A et al. (1993) A randomized trial of ivermectin versus albendazole for the treatment of cutaneous larva migrans. Am J Trop Med Hyg 49: 641–644

    PubMed  CAS  Google Scholar 

  4. Caumes E, Carriere J, Guermonprez G et al. (1995) Dermatoses associated with travel to tropical countries: a prospective study of the diagnosis and management of 269 patients presenting to a tropical disease unit. Clin Infect Dis 20: 542–548

    PubMed  CAS  Google Scholar 

  5. Coulaud JP, Binet D, Voyer C et al. (1982) Treatment of cutaneous larva migrans with albendazole. Bull Soc Pathol Exot 75: 534–537

    CAS  Google Scholar 

  6. Davies HD, Sakuls P, Keystone JS (1993) Creeping eruption. A review of clinical presentation and management of 60 cases presenting to a tropical diseases unit. Arch Dermatol 129: 558–591

    Article  Google Scholar 

  7. Guill M, Odom R (1978) Larva migrans complicated by Loffler’s syndrome. Arch Dermatol 114: 1525–1526

    Article  PubMed  CAS  Google Scholar 

  8. Hengge UR (2006) Cutaneous larva migrans. In: Tyring SK, Lupi O, Hengge UR (eds) Tropical Dermatology. Elsevier, Churchill Livingstone, pp 74–76

  9. Hotez PJ, Brooker S, Bethony JM et al. (2004) Hookworm infection. N Engl J Med 8: 799–807

    Article  Google Scholar 

  10. Hotez PJ, Narasimhan S, Haggerty J et al. (1992) Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans. Infect Immun 60: 1018–1023

    PubMed  CAS  Google Scholar 

  11. Jelinek T, Maiwald H, Nothdurft HD, Löscher T (1994) Cutaneous larva migrans in travelers: synopsis of histories, symptoms and treatment of 98 patients. Clin Infect Dis 19: 1062–1066

    PubMed  CAS  Google Scholar 

  12. Jensenius M, Maeland A, Brubakk O (2008) Extensive hookworm-related cutaneous larva migrans in Norwegian travelers to the tropics. Travel Med Infect Dis 6: 45–47

    PubMed  Google Scholar 

  13. Stone O, Mullins J (1965) Thiabendazole effectiveness in creeping eruption. Arch Dermatol 91: 427–429

    Article  PubMed  CAS  Google Scholar 

  14. Veraldi S, Rizzitelli G (1999) Effectiveness of a new therapeutic regimen with albendazole in cutaneous larva migrans. Eur J Dermatol 9: 352–353

    PubMed  CAS  Google Scholar 

  15. Welzel J (2005) Würmer. In: Braun-Falco O, Plewig G, Wolff HH et al. (Hrsg) Dermatologie und Venerologie. Springer, Berlin Heidelberg New York Tokyo, S 311–320

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to U.R. Hengge.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hoff, NP., Mota, R., Groffik, A. et al. Kutane Larva migrans. Hautarzt 59, 622–626 (2008). https://doi.org/10.1007/s00105-008-1514-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00105-008-1514-2

Schlüsselwörter

Keywords

Navigation