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Typ-I-Allergie auf Seminalplasma

Human seminal plasma allergy type I

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Zusammenfassung

Die humane Seminalplasmaallergie (HSPA) ist eine seltene allergische Reaktion auf spezifische Proteinfraktionen des Seminalplasma, wobei das prostataspezifische Antigen (PSA) als relevante allergene Determinante angesehen wird. Dabei treten in erster Linie Typ-I-Immunreaktionen mit lokaler und generalisierter Urtikaria sowie anaphylaktische Schocksymptome auf. Die Diagnostik basiert auf Anamnese, Klinik und Prick-Tests sowie Bestimmungen der spezifischen IgE-Werte nach Applikation von (un)fraktioniertem Seminalplasma. Wir berichten über eine Patientin mit rezidivierendem Auftreten einer generalisierten Urtikaria nach ungeschütztem Geschlechtsverkehr und 4fach positiver Prick-Test-Reaktion auf Seminalplasma.

Abstract

Human seminal plasma allergy (HSPA) is a rare allergic reaction to specific protein fractions of seminal plasma, whereof PSA seems to be a relevant allergen. Predominantly Type I-immunoreactions can occur. The main symptoms are localized and generalized urticaria and sometimes anaphylactic symptoms. The diagnosis is based on history, skin tests and on the determination of specific IgE-levels for (un)fractionated seminal plasma. Here we report a patient with recurrent episodes of generalized urticaria after unprotected sexual intercourse and positive prick-test-reaction on seminal plasma.

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Authors and Affiliations

  1. Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Leipzig AöR, Philipp-Rosenthal-Str. 23-25, 04103, Leipzig, Deutschland

    U.M. Winter, R. Treudler & J.C. Simon

  2. Klinik für Dermatologie und Phlebologie, Vivantes Klinikum, Berlin Friedrichshain, Berlin, Deutschland

    W. Harth

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  1. U.M. Winter
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  2. W. Harth
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  3. R. Treudler
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  4. J.C. Simon
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Correspondence to U.M. Winter.

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Winter, U., Harth, W., Treudler, R. et al. Typ-I-Allergie auf Seminalplasma. Hautarzt 59, 649–652 (2008). https://doi.org/10.1007/s00105-007-1429-3

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