Zusammenfassung
Keloide stellen gutartige Bindegewebsproliferationen dar, die meist nach einer Verletzung, aber auch spontan bzw. nach Mikrotraumen bei prädisponierten Patienten entstehen können. Im Unterschied zu hypertrophen Narben dehnen sich Keloide über die Grenze der ursprünglichen Verletzung hinaus aus und neigen nicht zur spontanen Rückbildung. Keloide sind häufig assoziiert mit Juckreiz und können durch ihr expansives und fibröses Wachstum nicht nur zu Funktionseinschränkung, Spannungsgefühl und Schmerzen führen, sondern auch zu kosmetischen und psychischen Problemen. Keloide sind eine therapeutische Herausforderung für den Dermatologen, da zwar zahlreiche Therapieoptionen zur Verfügung stehen, jedoch bis heute keine sicher wirksame, nebenwirkungsarme Therapie existiert. Im Folgenden wird auf die einzelnen Methoden der Keloidtherapie mit ihren Vor- und Nachteilen genauer eingegangen.
Abstract
Keloids are benign fibrous growths that appear after surgery, trauma or “spontaneously” as a consequence of microtrauma in predisposed patients. Keloids are distinguished from hypertrophic scars in that keloids extend beyond the margins of the original wound and do not tend to regress spontaneously. Keloids are often associated with pruritus and pain and can lead to functional and cosmetic deformities. Keloids are a therapeutic challenge for the dermatologist; although multiple treatment options are available, a reliably effective approach with few side effects remains elusive. High quality research in evaluating keloid therapy is also lacking. This article summarizes the methods used for the treatment of keloids showing their advantages and disadvantages.
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Karrer, S. Therapie von Keloiden. Hautarzt 58, 979–990 (2007). https://doi.org/10.1007/s00105-007-1406-x
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DOI: https://doi.org/10.1007/s00105-007-1406-x