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Atopie-Patch-Test mit Aeroallergenen und Nahrungsmitteln

Atopy patch testing with aeroallergens and food

Der Hautarzt volume 56, pages 1133–1140 (2005)Cite this article

Zusammenfassung

Der Atopie-Patch-Test (APT), ein Epikutantest mit Allergenen, die IgE-vermittelte Reaktionen auslösen können, und die Evaluation ekzematöser Hautreaktionen nach 24–72 h wurde für die Diagnostik von Patienten mit Aeroallergen-getriggertem atopischem Ekzem entwickelt. Positive APT-Reaktionen sind mit einer allergenspezifischen T-Zell-Antwort assoziiert. Die Spezifität des APT liegt im Vergleich zu den klassischen Tests der IgE-vermittelten Sensibilisierung (Prick-Test, RAST) höher. Insbesondere im Bereich der Nahrungsmittel-APT sind weitere Studien zur Standardisierung der Methodik erforderlich.

Abstract

The atopy patch test (APT), a patch test employing allergens known to elicit IgE-mediated reactions which is assessed by evaluating eczematous skin lesions after 24 h to 72 h, was developed as a diagnostic tool for characterizing patients with aeroallergen-triggered atopic eczema (AE, atopic dermatitis). Positive APT reactions are associated with allergen-specific T-cell responses. The specificity of APT is higher than the specificity of skin prick tests or RAST. More studies for the standardization of APT methods are necessary, especially with regard to food APT.

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Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein , Technische Universität München

    U. Darsow & J. Ring

  2. Klinische Kooperationsgruppe KKG/GSF, ZAUM — Zentrum für Allergie und Umwelt, München

    U. Darsow & J. Ring

  3. Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Biedersteiner Straße 29, 80802 , München

    U. Darsow

Authors
  1. U. Darsow
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  2. J. Ring
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Correspondence to U. Darsow.

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Darsow, U., Ring, J. Atopie-Patch-Test mit Aeroallergenen und Nahrungsmitteln. Hautarzt 56, 1133–1140 (2005). https://doi.org/10.1007/s00105-005-1055-x

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  • DOI: https://doi.org/10.1007/s00105-005-1055-x

Schlüsselwörter

  • Atopie-Patch-Test
  • Epikutantest
  • Atopisches Ekzem
  • Allergene
  • Aeroallergene
  • Nahrungsmittel

Keywords

  • Atopy patch test
  • Patch test
  • Atopic eczema
  • Allergens
  • Aeroallergens
  • Food