Skip to main content
Log in

Evidenzbasierte Dermatologie und die Cochrane Skin Group

  • Leitthema
  • Published:
Der Hautarzt Aims and scope Submit manuscript

Zusammenfassung

Das Konzept der evidenzbasierten Medizin hat in den letzten 10 Jahren zu einem Paradigmenwechsel im ärztlichen Denken und Praktizieren geführt. Inzwischen ist es modern geworden, von evidenzbasierter Medizin zu sprechen. Leider hat dies auch dazu geführt, dass der Begriff evidenzbasierte Medizin häufig falsch verstanden, nicht richtig angewandt, ja sogar missbraucht wird. Dieser Übersichtartikel versucht daher klarzustellen, was evidenzbasierte Dermatologie ist und was sie nicht ist. Dabei werden praktische Hinweise zu den vier Kernschritten gegeben, die für ein erfolgreiches Praktizieren evidenzbasierter Dermatologie notwendig sind. Es wird auf die zentrale Rolle systematischer Reviews eingegangen und die Arbeit der Cochrane Skin Group vorgestellt. Ergänzend werden aber auch die Limitationen der evidenzbasierten Dermatologie aufgezeigt.

Abstract

The concept of evidence based medicine (EBM) has represented a paradigm shift in medical thinking and practise in the last decade. However, we seem to be stuck with the phrase, yet it is a term that is frequently abused and misunderstood. Therefore, the purpose of this article is to clarify what evidence based dermatology (EBD) is and what it is not. Some guidance on the four key steps in practising EBM in dermatology will be given. The central role of systematic reviews will be elaborated and the Cochrane skin group introduced. Finally, the limitation of EBD will be discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Adetugbo K, Williams HC (2000) How well are randomised controlled trials reported in the dermatology literature. Arch Dermatol 136:381–385

    Article  Google Scholar 

  2. Delamere FM, Williams HC (2001) How can hand searching the dermatological literature help people with skin problems. Arch Dermatol 137:332–335

    Google Scholar 

  3. Drummond MF, Richardson WF, O’Brian B, Levine M, Heyland D for the Evidence-Based Medicine Working Group (1997) User’s guide to the medical literature. How to use an economic analsis. JAMA 277:1552–1557

    Article  CAS  PubMed  Google Scholar 

  4. Feinstein AR, Horwitz RI (1997) Problems in the „evidence“ of „evidence-based medicine“. Am J Med 103:529–535

    Article  Google Scholar 

  5. Greenhalgh T (1997) How to read a Paper. BMJ, London

  6. Hoare C, Li Wan Po A, Williams H (2000) Systematic review of treatments for atopic eczema. Health Technol Assess 4 (37)

  7. Jaeschke R, Guyatt GH, Sackett DL for the Evidence-Based Medicine Working Group (1994). User’s guide to the medical literature. III. How to use an article about a diagnostic test. A: Are the results of the study valid. JAMA 271:389–391

    Article  Google Scholar 

  8. Juni P, Altman DG, Egger M (2001) Assessing the quality of controlled clinical trials. BMJ 323:699–700

    Article  Google Scholar 

  9. Laupacis A, Well G, Richardson WS, Tugwell P for the Evidence-Based Medicine Working Group (1994) User’s guide to the medical literature V. How to use an article about prognosis. JAMA 272:234–237

    Article  Google Scholar 

  10. Naldi L, Svensson A, Diepgen T et al. (2003) On behalf of The European Dermato-Epidemiology Network (EDEN): Randomized Clinical Trials for Psoriasis 1977–2000: the EDEN Survey. J Invest Dermatol 120:738–741

    Article  Google Scholar 

  11. Rees J (2000) Evidence-based medicine: the epistemology that isn’t. J Am Acad Dermatol 43:727–729

    Article  Google Scholar 

  12. Rosenberg W, Donald A (1995) Evidence-based medicine: an approach to clinical problem solving. BMJ 310:1122–1126

    Google Scholar 

  13. Sackett DL, Rosenberg Q, Gray JA, Haynes RB, Richardson WS (1996) Evidence-based medicine: what it is and what it isn’t. BMJ 312:71–72

    CAS  PubMed  Google Scholar 

  14. Sackett DL, Richardson WS, Rosenberg Q, Haynes RB (1997) Evidence-based medicine. How to practice and teach EBM. Churchill Livingston, London

  15. Seidman D (2001) Compliance with guidelines is not the same as evidence-based medicine. J Paediatrics 138:299–300

    Article  Google Scholar 

  16. Shaughnessy AR, Slawson DC, Bennett HJ (1994) Becoming an information master: a guidebook to the medical information jungle. J Fam Prac 39:489–499

    CAS  PubMed  Google Scholar 

  17. Van Coevorden AM, Coenraads PJ, Svensson A et al. (2004) Overview of studies of treatments for hand eczema—the EDEN hand eczema survey. Br J Dermatol 151:446–451

    Article  Google Scholar 

  18. Williams HC (2003) Applying trial evidence back to the patient. Arch Dermatol 139:1195–1200

    Article  Google Scholar 

  19. Williams HC, Seed P (1993) Inadequate size of „negative“ clinical trials in dermatology. Br J Dermatol 128:317–326

    Google Scholar 

  20. Williams HC, Adetugbo K, Alain Li Wan Po et al. (1998) The Cochrane Skin Group: Preparing, maintaining and disseminating systematic reviews of clinical interventions in dermatology. Arch Dermatol 134:1620–1626

    Article  Google Scholar 

  21. Williams HC, Bigby M, Diepgen TL, Herxheimer A, Naldi L, Rzany B (2003) Evidence based dermatology. BMJ, London

Download references

Interessenkonflikt:

Keine Angaben

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to T. L. Diepgen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Diepgen, T.L., Williams, H.C. Evidenzbasierte Dermatologie und die Cochrane Skin Group. Hautarzt 56, 251–257 (2005). https://doi.org/10.1007/s00105-005-0900-2

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00105-005-0900-2

Schlüsselwörter

Keywords

Navigation