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Evidenzbasierte Therapie von Herpes-Virus-Erkrankungen der Haut

Evidence-based treatment of skin diseases caused by herpesvirus

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Zusammenfassung

Im vorliegenden Beitrag werden sechs praxisrelevante Fragen zu Varizella-Zoster-Virus-bedingten Erkrankungen formuliert und evidenzbasiert beantwortet. Datenbasen (Stand 1/2005) waren die „Cochran Library“, „MEDLINE“, „Clinical Evidence“ und verschiedene Leitlinienanbieter. Die Hierarchie des Evidenzniveaus wurde entsprechend den „Oxford Centre for Evidence-based Medicine Levels of Evidence“ gewichtet. Der aktuelle Stand zu antiviraler Therapie bei immunkompetenten Kindern, Erwachsenen und Schwangeren mit Varizellen, zur Aktivimpfung gegen Varizellen im Kindesalter, zu Therapiebeginn bei akutem Zoster und zur Auswirkung der Verabreichungsroute auf postzosterische Schmerzen werden behandelt.

Abstract

Six questions regarding varicella-zoster virus-related skin diseases are addressed. The Cochran Library, MEDLINE, Clinical Evidence and several guideline providers were searched for evidence. The level of evidence in papers was appraised according to the Oxford Centre for Evidence-based Medicine Levels of Evidence. The current evidence for antiviral therapy of chickenpox in immunocompetent children, adults and pregnancy, recommendation of varicella vaccination, effect of time of initiation of antiviral therapy in acute zoster as well as route of treatment with regard to onset of post-zoster neuralgia are covered.

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  1. Dermatologische Klinik mit Poliklinik, Universitätsklinikum, Erlangen

    V. Mahler

  2. Dermatologische Klinik mit Poliklinik, Universitätsklinikum Erlangen, Hartmannstraße 14, 91052, Erlangen

    V. Mahler

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Correspondence to V. Mahler.

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Mahler, V. Evidenzbasierte Therapie von Herpes-Virus-Erkrankungen der Haut. Hautarzt 56, 241–250 (2005). https://doi.org/10.1007/s00105-005-0899-4

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  • DOI: https://doi.org/10.1007/s00105-005-0899-4

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