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IgA-Pemphigus

Erfolgreiche Behandlung mit Mycophenolat mofetil

IgA pemphigus

Successful treatment with mycophenolate mofetil

Der Hautarzt volume 55, pages 387–389 (2004)Cite this article

Zusammenfassung

Der IgA-Pemphigus ist eine seltene, intraepidermale Autoimmundermatose, die durch interzelluläre IgA-Ablagerungen, intraepidermale Akantholyse mit Neutrophileninfiltration und zirkulierenden IgA-Autoantikörpern gegen Oberflächenstrukturen der Keratinozyten gekennzeichnet ist. Wir berichten zum 1. Mal über einen Patienten mit einem aggressiv verlaufenden IgA-Pemphigus, bei dem eine Behandlung mit Mycophenolat mofetil zur Rückbildung der Hautveränderungen bei stabilem Krankheitsverlauf führte.

Abstract

IgA pemphigus is a rare intraepidermal autoimmune disease characterized by the presence of intercellular IgA deposits, intraepidermal acantholysis with infiltration of neutrophils, and circulating IgA autoantibodies against keratinocyte cell surface components. We report for the first time about a patient with IgA pemphigus who was successfully treated with mycophenolate mofetil.

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Affiliations

  1. Hautklinik, Universitätskinikum Düsseldorf, Düsseldorf

    T. Burchardt, A. Büchau, T. Ruzicka &  M. Megahed

  2. Hautklinik, Universitätskinikum Düsseldorf, Moorenstraße 5, 40225 , Düsseldorf

    M. Megahed

Authors
  1. T. Burchardt
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  2. A. Büchau
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  3. T. Ruzicka
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  4. M. Megahed
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Correspondence to M. Megahed.

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Burchardt, T., Büchau, A., Ruzicka, T. et al. IgA-Pemphigus. Hautarzt 55, 387–389 (2004). https://doi.org/10.1007/s00105-004-0713-8

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  • DOI: https://doi.org/10.1007/s00105-004-0713-8