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Multiples Autoimmunsyndrom

Assoziation eines Reynolds-Syndroms (akrale Sklerodermie, primär biliäre Zirrhose, Sjögren-Syndrom) mit einem Lupus erythematodes/Lichen-ruber-planus-Overlap-Syndrom

Multiple autoimmune syndrome

Reynolds’ syndrome (acral scleroderma, primary biliary cirrhosis, Sjögren syndrome) associated with the lupus erythematosus/lichen planus overlap syndrome

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Zusammenfassung

Wir beschreiben eine Patientin mit einer akralen Sklerodermie, Sjögren-Syndrom, spezifischen Antikörpern einer primär biliären Zirrhose und klinischen und histologischen Charakteristika eines Lichen ruber und eines subakuten Lupus erythematodes. Außerdem besteht eine euthyreote Hashimoto-Thyreoiditis. Der vorgestellte Fall entspricht dem Typ II des multiplen Autoimmunsyndroms (MAS) und kann als Assoziation von 2 bekannten Überlappungssyndromen betrachtet werden: dem Reynolds-Syndrom und dem Lupus erythematodes/Lichen-ruber-planus-Overlap-Syndrom.

Abstract

A female patient presented with acral scleroderma, Sjögren syndrome, antibodies specific for primary biliary cirrhosis and clinical as well as histological features of lichen planus and subacute lupus erythematosus. In addition an euthyroid Hashimoto thyroiditis was found. Her findings correspond to type II of the multiple autoimmune syndrome (MAS) and can be described as an association of Reynolds syndrome and the lupus erythematosus/lichen planus-overlap syndrome.

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Notes

  1. Mindestens 3 Erkrankungen einer Gruppe müssen vorliegen

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Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.

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Authors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Venerologie Universität Köln, Köln

    F. B. Müller, W. Groth & G. Mahrle

  2. Klinik und Poliklinik für Dermatologie und Venerologie, Universität Köln, Joseph-Stelzmann-Straße 9, 50924 , Köln

    F. B. Müller

Authors
  1. F. B. Müller
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  2. W. Groth
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  3. G. Mahrle
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Correspondence to F. B. Müller.

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Müller, F.B., Groth, W. & Mahrle, G. Multiples Autoimmunsyndrom. Hautarzt 55, 465–470 (2004). https://doi.org/10.1007/s00105-003-0663-6

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  • DOI: https://doi.org/10.1007/s00105-003-0663-6

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