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Atopisches Ekzem

Provokationsfaktoren und Möglichkeiten ihrer wirkungsvollen Reduktion bzw. Elimination

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Zusammenfassung

Das atopische Ekzem gehört mit dem Asthma bronchiale und der Rhinoconjunctivitis allergica zu der Trias der atopischen Erkrankungen. Grundlegender pathogenetischer Faktor ist die genetische Disposition. Erst das Vorliegen von Provokationsfaktoren führt jedoch zur Realisation der Erkrankung, das heißt zum Auftreten von Hauterscheinungen. Neben der stadiengerechten Therapie der Erkrankung spielt im modernen Krankheitsmanagement die Beachtung von Auslösern eine wesentliche Rolle, deren konsequente Aufdeckung und Vermeidung Krankheitsschübe mildern oder sogar ganz verhindern kann. Das Spektrum der in Frage kommenden Provokationsfaktoren erstreckt sich hierbei von im Alltag einfach umzusetzenden Ratschlägen, wie z. B. der richtigen Auswahl der Kleidung, bis hin zu spezifischen Maßnahmen wie der Aeroallergenreduktion in Innenräumen und Diätempfehlungen.

Abstract

Atopic eczema forms together with extrinsic bronchial asthma and allergic rhinoconjunctivitis the classical atopic triad. Genetic predisposition is the crucial pathogenetic factor. The combination of genetic disposition and provocation factors leads to the clinical appearance of skin disease. In addition to therapy adjusted to the stage of the disease, modern management should include a search for relevant trigger factors and then their avoidance to reduce or even prevent flares of the disease. The spectrum of provocation factors ranges from simple measures such as appropriate clothing up to specific measures such as indoor aeroallergen reduction measures.

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Fischer, S., Ring, J. & Abeck, D. Atopisches Ekzem. Hautarzt 54, 914–924 (2003). https://doi.org/10.1007/s00105-003-0557-7

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