Zusammenfassung
Die Lobektomie mit Bronchusmanschettenresektion ist ein etabliertes operatives Verfahren bei zentralen Lungenkarzinomen. Häufig ist die chirurgische Alternative zu diesem Eingriff die Pneumonektomie. Beschrieben wird das perioperative Risiko und das funktionelle Ergebnis nach Lobektomie mit Bronchusmanschettenresektion im Vergleich zur typischen Lobektomie und Pneumonektomie.
In Bezug auf die postoperative Morbidität unterscheiden sich die Eingriffe nur wenig. Allerdings ist die Letalität der Patienten nach Pneumonektomie deutlich höher. Bronchopleurale Fisteln treten bei Lobektomie und Manschettenlobektomie in vergleichbar hohen Raten auf, nach Pneumonektomie ist die Rate wesentlich höher. Gefürchtet bleibt die bronchovaskuläre Fistel nach Manschettenresektion. Funktionell entsprechen die postoperativen Werte der Manschettenlobektomie denen der Lobektomiepatienten und sind deutlich besser als nach Pneumonektomie.
Wenn möglich, ist die Manschettenresektion mit Lobektomie der Pneumonektomie vorzuziehen.
Abstract
Sleeve lobectomy is an established surgical procedure in patients with lung cancer. Usually the only surgical alternative would be a pneumonectomy. This article describes the perioperative risks and functional results in patients after sleeve lobectomy compared to pneumonectomy and typical lobectomy.
There were only minor differences with respect to postoperative morbidity comparing the different procedures but the mortality rate was higher following pneumonectomy. Bronchopleural fistula rates were also similar comparing lobectomy and sleeve lobectomy but elevated following pneumonectomy. Bronchovascular fistulas after sleeve lobectomy are potentially life-threatening. Postoperative pulmonary function tests showed similar values for lobectomy and sleeve lobectomy patients and were considerably better than following pneumonectomy.
Whenever possible sleeve lobectomy should take preference over pneumonectomy.
Literatur
Algar FJ, Alvarez A, Aranda JL et al (2001) Prediction of early bronchopleural fistula afterpneumonectomy: a multivariate analysis. Ann Thorac Surg 72(5):1662–1667
Asamura H, Naruke T, Tsuchiya R et al (1992) Bronchopleural fistulas associated with lung cancer operations. Univariate and multivariate analysis of risk factors, management, and outcome. J Thorac Cardiovasc Surg 104:1456–1464
Balduyck B, Hendriks J, Lauwers P et al (2008) Quality of life after lung cancer surgery: a prospective pilot study comparing bronchial sleeve lobectomy with pneumonectomy. J Thorac Oncol 3(6):604–608
Bölükbas S, Schirren J (2010) Parenchyma-sparing bronchial sleeve resection in trauma, benign and malign diseases. Thorac Cardiovasc Surg 58:32–37
Braga KA, Nepomuceno NA, Correia AT et al (2012) The effects on mucociliary clearance of prednisone associated with bronchial section. Clinics 67(6):647–652
Deslauriers J, Gaulin P, Beaulieu M et al (1986) Long-term clinical and functional results of sleeve lobectomy for primary lung cancer. J Thorac Cardiovasc Surg 92(5):871–879
Fadel E, Yildizeli B, Chapelier AR et al (2002) Sleeve lobectomy for bronchogenic cancers: factors affecting survival. Ann Thorac Surg 74(3):851–858
Gaissert HA, Mathisen DJ, Moncure AC et al (1996) Survival and function after sleeve lobectomy for lung cancer. J Thorac Cardiovasc Surg 117:948
Harpole DH, DeCamp MM, Daley J et al (1999) Prognostic models of thirty-day mortality and morbidity after major pulmonary resections. J Thorac Cardiovasc Surg 117:969–979
Hollaus PA, Wilfing G, Wurnig PN et al (2003) Risk factors for the development of postoperative complications after bronchial sleeve resection for malignancy: a univariate and multivariate analysis. Ann Thorac Surg 75(3):966–972
Inui K, Wada H, Yokomise H, Lee M et al (1990) Evaluation of a bronchial anastomosis by laser Doppler velocimetry. J Thorac Cardiovasc Surg 99(4):614–619
Khargi K, Duurkens VA, Versteegh MI et al (1994) Pulmonary function after sleeve lobectomy. Ann Thorac Surg 57:1302
Kimm YT, Kang CH, Sung SW et al (2005) Local control of disease related to lymph node involvement in non-small cell lung cancer after sleeve lobectomy compared with pneumonectomy. Ann Thorac Surg 79:1153–1161
Lange M, Hamahata A, Traber DL et al (2011) Preclinical evaluation of epinephrine nebulization to reduce airway hyperemia and improve oxygenation after smoke inhalation injury. Crit Care Med 39(4):718–724
Lausberg HF, Graeter TP, Wendler O et al (2000) Bronchial and bronchovascular sleeve resection for treatment of central lung tumors. Ann Thorac Surg 70:367–372
Lausberg HF, Graeter TP, Tscholl D et al (2005) Bronchovascular versus bronchial sleeve resection for central lung tumors. Ann Thorac Surg 79:1147–1152
Lee HK, Lee HS, Kim KI et al (2011) Outcomes of sleeve lobectomy versus pneumonectomy for lung cancer. Korean J Thorac Cardiovasc Surg 44(6):413–417
Ludwig C, Riedel R, Schnell J et al (2009) Inhalation with Tobramycin® to improve healing of tracheobronchial reconstruction. Eur J Cardiothorac Surg 35:797–800
Rendina EA, Venuta F, Ricci C (1992) Effects of low-dose steroids on bronchial healing after sleeve resection. A clinical study. J Thorac Cardiovasc Surg 104:888–891
Romano PS, Mark DH (1992) Patient and hospital characteristics related to in-hospital mortality after lung cancer resection. Chest 101(5):1332–1337
Schäfers HJ, Haverich A, Wagner TO et al (1992) Decreased incidence of bronchial complications following lung transplantation. Eur J Cardiothorac Surg 6(4):174–178
Schirren J, Bölükbas S, Bergmann T et al (2009) Prospective study on perioperative risks and functional results in bronchial and bronchovascular sleeve resection. Thorac Cardiovasc Surg 57:35–41
Schirren J, Eberlein M, Fischer A et al (2011) The role of sleeve resections in advanced nodal disease. Eur J Cardiothorac Surg 40:1157–1164
Sirbu H, Busch T, Aleksic I et al (2001) Bronchopleural fistula in the surgery of non-small cell lung cancer: incidence, risk factors, and management. Ann Thorac Cardiovasc Surg 7:330–336
Spiguel L, Ferguson K (2007) Sleeve lobectomy versus pneumonectomy for lung cancer in patients with good pulmonary function. In: Ferguson MK (Hrsg) Difficult decisions in thoracic surgery. Springer, London, S 103–109
Storelli E, Tutic M, Kestenholz P et al (2012) Sleeve resections with unprotected bronchial anastomoses are safe even after neoadjuvant therapy. Eur J Cardiothorac Surg 42(1):77–81
Tedder M, Anstadt MP, Tedder SD et al (1992) Current morbidity, mortality, and survival after bronchoplastic procedures for malignancy. Ann Thorac Surg 54(2):387–391
Tronc F, Grégoire J, Rouleau J et al (2000) Long term results of sleeve lobectomy for lung cancer. Eur J Cardiothorac Surg 17:550
Wada H, Nakamura T, Nakamoto K et al (1998) Thirty-day operative mortality for thoracotomy in lung cancer. J Thorac Cardiovasc Surg 115:70–73
Yildizeli B, Fadel E, Mussot S et al (2007) Morbidity, mortality, and long-term survival after sleeve lobectomy for non-small cell lung cancer. Eur J Cardiothorac Surg 31(1):95–102
Andrighetti N, Nepomuceno N, Correia A et al (2012) The effects on mucociliary clearance of prednisone associated with bronchial section. Clinics 67:647-651
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Graeter, T. Bronchusmanschettenresektion. Chirurg 84, 469–473 (2013). https://doi.org/10.1007/s00104-012-2429-0
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DOI: https://doi.org/10.1007/s00104-012-2429-0