Zusammenfassung
Das reine Plattenepithelkarzinom des Kolons ist mit einer Inzidenz von weniger als 0,025% der Dickdarmmalignome eine extreme seltene histopathologische Entität. Eine Schleimhautmetaplasie soll der Entstehung des Plattenepithelkarzinoms zugrunde liegen. Die Diagnose gleicht der des Adenokarzinoms. Die operative Behandlung steht im Vordergrund. Im fortgeschrittenen Stadium wird eine adjuvante Radiochemotherapie empfohlen. Die Prognose des fortgeschrittenen Plattenepithelkarzinoms scheint schlechter als die des fortgeschrittenen Adenokarzinoms zu sein.
Abstract
Squamous cell carcinoma of the colon is an extremely rare histopathological entity accounting for less than 0.025% of all colonic malignancies. Mucosal metaplasia is believed to be the leading cause of this form of carcinoma and the presentation and diagnosis is the same as for adenocarcinoma. Surgery is the treatment method of choice and adjuvant radiation and chemotherapy are recommended in advanced stages of the disease. Advanced squamous cell carcinoma seems to have a poorer prognosis compared to advanced adenocarcinoma.
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Ambe, P., Shadouh, S., Granetzny, S. et al. Reines Plattenepithelkarzinom des Rektums. Chirurg 82, 1116–1119 (2011). https://doi.org/10.1007/s00104-010-2048-6
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DOI: https://doi.org/10.1007/s00104-010-2048-6