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Peritonealmetastasen in der pathologisch-anatomischen Befundung

Pathologic and anatomic evidence of peritoneal metastases

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Zusammenfassung

Peritonealmetastasen sind sekundäre Tumoren des Peritoneums und stellen die häufigste Tumorentität dieser Lokalisation dar. Tumoren, die typischerweise peritoneal metastasieren, sind das Ovarialkarzinom, das kolorektale Karzinom und das Magenkarzinom neben Karzinomen des Pankreas, der Gallenblase, des Uterus und der Lunge. Von den Peritonealmetastasen abzugrenzen sind die seltenen primären malignen Tumoren des Peritoneums wie das primäre maligne peritoneale Mesotheliom oder das primäre peritoneale Karzinom neben benignen Tumoren des Peritoneums sowie nicht neoplastischen, vorwiegend entzündlichen Veränderungen. Eine Differenzierung zwischen einem primären Tumor des Peritoneums und Peritonealmetastasen ist, insbesondere beim CUP („cancer of unknown primary“) -Syndrom, schwierig und gelingt häufig nur mittels immunhistochemischer Zusatzuntersuchungen.

Abstract

Peritoneal metastases are secondary tumours of the peritoneum and the most common tumours at this location. Ovarian carcinoma, colorectal cancer, and gastric cancer are the most frequent ones that show peritoneal involvement, along with carcinomas of the pancreas, gallbladder, uterus, and lung. Primary tumours originating in the peritoneum such as malignant peritoneal mesothelioma, primary peritoneal carcinoma, and benign peritoneal tumours along with inflammatory and reactive lesions must be differentiated from peritoneal metastases. Especially in cancer of unknown primary tumour, the discrimination between primary peritoneal tumours and peritoneal metastases is difficult and often requires immunhistochemical identification.

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Tischoff, I., Tannapfel , A. Peritonealmetastasen in der pathologisch-anatomischen Befundung. Chirurg 78, 1085–1090 (2007). https://doi.org/10.1007/s00104-007-1427-0

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