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Klinisches Staging der Peritonealkarzinose durch Scoringsysteme

Eine kritische Analyse

Scoring systems for clinical staging of peritoneal carcinomatosis

A critical analysis

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Zusammenfassung

Im Rahmen des klinischen Stagings zur Beschreibung des Umfangs einer Peritonealkarzinose, der bei zytoreduktiver Chirurgie notwendigen Maßnahmen und des erzielten Ergebnisses in Form der Vollständigkeit der chirurgischen Zytoreduktion stehen unterschiedliche Klassifikations- und Scoringsysteme zur Verfügung. Die höchste klinische Relevanz bei der Peritonealkarzinose gastrointestinaler Tumoren haben Klassifikationen zur Tumorausdehnung und zur Vollständigkeit der chirurgischen Tumorresektion. Zumeist erfolgt eine Zuordnung der Patienten in die entsprechenden Stadien aufgrund der intraoperativen Evaluation und ist daher subjektiv. Die unterschiedlichen Klassifikationen werden dargestellt und hinsichtlich ihrer Anwendbarkeit, Genauigkeit und ihrer Wertigkeit als Selektionsinstrument sowie ihrer Aussagefähigkeit zur Prognose diskutiert und verglichen.

Abstract

For peritoneal carcinomatosis, several different classification and scoring systems for clinical staging have been proposed and used by the different centers worldwide engaged in treating this clinical entity. Of highest clinical relevance are the classifications assessing tumor distribution and size and those describing the degree of surgical cytoreduction. Allocation of patients to different stages is based on clinical intraoperative evaluation and therefore is subjective and observer-dependent. The various classification systems are presented and discussed regarding applicability, exactness, and their value as either selection criterion or prognostic instrument.

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Jähne, J., Kübler, S. Klinisches Staging der Peritonealkarzinose durch Scoringsysteme. Chirurg 78, 1091–1099 (2007). https://doi.org/10.1007/s00104-007-1426-1

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  • DOI: https://doi.org/10.1007/s00104-007-1426-1

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