Zusammenfassung
In diesem Beitrag werden aktuelle evidenzbasierte Behandlungsempfehlungen für die akute und chronische Ischämie der unteren Extremitäten vor dem Hintergrund der Möglichkeiten endovaskulärer Techniken und offen-gefäßchirurgischer Strategien präsentiert. Neben der Darstellung des Spannungsbogens zwischen den differenten therapeutischen Möglichkeiten werden auch die Vorteile der Kombination beider Techniken (endovaskuläre Kombinations- oder „Hybridtherapie“) beschrieben.
Sowohl für die akute Ischämie als auch für die periphere arterielle Verschlusskrankheit werden die unterschiedlichen Therapieprinzipien entlang der verschiedenen Gefäßsegmente diskutiert. Allgemein kann konstatiert werden, dass die aortoiliakale Revaskularisation bei chronischen Obstruktionen vermehrt durch endovaskuläre Techniken oder Hybridverfahren von einem minimal-invasiven Zugang über die Femoralisgabel therapiert werden, während die akute Okklusion in diesem Segment weiterhin mittels offener Techniken (Ballonthrombektomie nach Fogarty) behandelt werden. Im infrainguinalen Segment sind bei chronischer Ischämie die endovaskulären Therapieprinzipien auf dem Vormarsch, wobei Mehretagenverschlüsse, langstreckige Okklusionen im femoralen und poplitealen Segment unverändert durch Bypasstechniken behandelt werden. Die akute Ischämie im infrainguinalen Segment wird zunehmend initial mittels endovaskulärer Methoden (Lyse und perkutane Thrombektomie) therapiert.
Abstract
In this article, current evidence-based treatment recommendations for acute and chronic lower limb ischemia will be presented considering the varied possibilities of endovascular techniques and open surgical vascular strategies. Beside presentation of the different therapeutic possibilities, advantages of the combination of both techniques will be described. Despite the BASIL trial, there are no prospective randomised controlled trials comparing endovascular and open surgical interventions. Different therapeutic rules along the different vascular segments will be discussed for both acute and chronic peripheral arterial disease. Generally it can be stated that aortoiliac revascularization for chronic obstructions is increasingly being carried out by endovascular means or hybrid procedures using a minimally invasive femoral approach, whereas acute occlusions in this vascular segment are still treated with open surgical techniques (Fogarty balloon thrombectomy). In the infrainguinal region, endovascular therapeutic strategies are gaining favor. However, multilevel occlusions and long-segment obstructions in the femoral and popliteal segment are still treated by bypass procedures. Acute ischemia in the infrainguinal segment is increasingly treated with endovascular methods (local thrombolysis and percutaneous thrombectomy).
Literatur
Norgren L, Hiatt WR, Dormandy JA et al. (2007) Inter-society consensus for the management of peripheral arterial disease (TASC II). J Vasc Surg [Suppl S] 45: 5–67
Vorwerk D, Günther RW, Schürmann K et al. (1995) Primary stent placement for chronic iliac artery occlusions: follow-up results in 103 patients. Radiology 194: 745–749
Tetteroo E, Graaf Y van der, Bosch JL et al. (1998) Randomised comparison of primary stent placement versus primary angioplasty followed by selective stent placement in patients with iliac-artery occlusive disease. Lancet 351: 1153–1159
Saxon RR, Coffman JM, Gooding JM et al. (2003) Long-term results of ePTFE stent-graft versus angioplasty in the femoropopliteal artery: single center experience from a prospective, randomized trial. J Vasc Interv Radiol 14: 303–311
Duda SH, PusischB, Richter G et al. (2002) Sirolismus-eluting stents for the treatment of obstructive superficial femoral artery disease: six-month results. Circulation 106: 1505–1509
Ansel GM, Sample NS, Botti III JF Jr et al. (2004) Cutting balloon angioplasty of the popliteal and infrapopliteal vessels for symptomatic limb ischemia. Catheter Cardiovasc Interv 61: 1–4
Laird J, Jaff MR, Biamino G et al. (2005) Cryoplasty for the treatment of femoropopliteal arterial disease: results of a prospective, multicenter registry. J Vasc Interv Radiol16: 1067–1073
Kedora J, Hohmann S, Garrett W et al. (2007) Randomized comparison of percutaneous viabahn stent grafts vs. prosthetic femoral-popliteal bypass in the treatment of superficial femoral arterial occlusive disease. J Vasc Surg 45: 10–16
Griffiths GD, Nagy J, Black D, Stonebridge PA (2004) Randomized clinical trial of distal anastomotic interposition vein cuff in infrainguinal polytetrafluoroethylene bypass grafting. Br J Surg 91: 560–562
Hiatt WR (2001) Medical treatment of peripheral arterial disease and claudication. N Engl J Med 344: 1608–1621
Szilagyi DE, Elliot JP Jr, Smith RF et al. (1986) A thirty-year-survey of the reconstructive surgical treatment of aortoiliac occlusive disease. J Vasc Surg 3: 421–436
Feugier P, Toursarkissian B, Chevalier JM et al. (2003) Endovascular treatment of isolated atherosclerotic stenosis of the infrarenal abdominal aorta: long-term outcome. Ann Vasc Surg 17: 375–385
Nelson PR, Powell RJ, Schermerhorn ML et al. (2002) Early results of external iliac artery stenting combined with common femoral artery enarterectomy. J Vasc Surg 25: 1107–1113
Cotroneo AR, Iezzi R, Marano G et al. (2007) Hybrid therapy in patients wiith complex peripheral multifocal steno-obstructive vascular disease: two-year results. Cardiovasc Intervent Radiol 30: 355–361
Schillinger M, Sabeti S, Loewe C et al. (2006) Balloon angioplasty versus implantation of nitinol stents in the superficial femoral artery. N Engl J Med 354: 1879–1888
Johnson WC, Lee KK (2000) A comparative evaluation of polytetrafluoroethylene, umbilical vein and saphenous vein bypass grafts for femoral-popliteal above-knee revascularization: a prospective randomized Department of Veterans Affairs cooperative study. J Vasc Surg 32: 268–277
Dormandy JA, Rutherford RB (2000) Management of peripheral arterial disease (PAD). TASC Working Group. TransAtlantic Inter-Society Concensus (TASC). J Vasc Surg 31: S1–S296
Söder HK, Manninen HI, Jaakkola P et al. (2000) Prospective trial of infrapopliteal artery balloon angioplasty for critical limb ischemia: angiographic and clinical results. J Vasc Interv Radiol 11: 1021–1031
Dorros G, Jaff MR, Dorros AM et al. (2001) Tibioperoneal (outflow lesion) angioplasty can be used as primary treatment in 235 patients with critical limb ischemia: five-year follow-up. Circulation 104: 2057–2062
Adam DJ, Beard JD, Cleveland T et al. (2005) Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised, controlled trial. Lancet 366: 1925–1934
Laird JR, Zeller T, Gray BH et al. (2006) Limb salvage following laser-assisted angioplasty for critical limb ischemia: results of the LACI multicenter trial. J Endovasc Ther 13: 1–11
Duda SH, Bosiers M, Lammer J et al. (2006) Drug-eluting and bare nitinol stents for the treatment of atherosclerotic lesions in the superficial femoral artery: long-term results from the SIROCCO trial. J Endovasc Ther 13: 701–710
Ouriel K, Veith FJ, Sasahara AA et al. (1998) A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the leg. N Eng J Med 338: 1105–1111
Starck EE, McDermott JC, Crummy AB et al. (1985) Percutaneous aspiration thromboembolectomy. Radiology 156: 61–66
Wagner HJ, Starck EE (1992) Acute embolic occlusions of the infrainguinal arteries: percutaneous aspiration embolectomy in 102 patients. Radiology 182: 403–407
Wagner HJ, Müller-Hülsbeck S, Pitton MB et al. (1997) Rapid thrombectomy with a hydrodynamic catheter: results from a prospective multicenter trial. Radiology 205: 675–681
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Storck, M., Wagner, HJ. Periphere arterielle Verschlusskrankheit und akute Extremitätenischämie. Chirurg 78, 611–619 (2007). https://doi.org/10.1007/s00104-007-1369-6
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00104-007-1369-6
Schlüsselwörter
- Akute Extremitätenischämie
- Chirurgische Revaskularisation
- Endovaskuläre Therapie
- Periphere arterielle Verschlusskrankheit
- TASC-Dokument