Skip to main content
Log in

Primäre Varikose

Primary varicosis

  • Leitthema
  • Published:
Der Chirurg Aims and scope Submit manuscript

Zusammenfassung

Die klassische Varizenoperation gilt noch heute als Goldstandard in der operativen Therapie der Varikose. Die Ergebnisse dieses Verfahren sind hinsichtlich der Komplikationen als sehr gut zu bewerten. Die Rezidivrate wird in der Literatur zwischen 6 und 60% in Abhängigkeit zum Nachuntersuchungszeitraum angegeben. Die wahre Rezidivrate ist jedoch unbekannt, da eine einheitliche Definition bislang fehlt. Die endovaskulären Verfahren zur Ausschaltung der Stammvenen – Radiofrequenzobliteration und Lasertherapie – haben sich als alternative, wenig invasive Verfahren mittlerweile etabliert. Bis zu 2 bzw. 5 Jahren postoperativ werden gute Ergebnisse publiziert, die denen der klassischen Varizenoperation vergleichbar sind. Der Vorteil der endovaskulären Verfahren scheint vor allem in der geringeren Invasivität und damit in der geringeren Beeinträchtigung der Lebensqualität im Vergleich zur klassischen Operation zu bestehen. Die Verbesserung der Lebensqualität von Patienten mit Varikose nach Operation ist aber auch für die klassische Varizenoperation bewiesen.

Die Bandbreite in der operativen Behandlung der Stamm- und Seitenastvarikose ist durch die neuen technischen Entwicklungen deutlich größer geworden. Für den Operateur bedeutet dies, dass der Patient gewissenhaft über die Vor- und Nachteile sowie die Ergebnisse der einzelnen Methoden aufgeklärt werden sollte und der Operateur sehr genau abwägen muss, welche Methode für den Patienten derzeit die beste darstellt.

Abstract

The classic varicose vein operation still represents the “gold standard” in the operative therapy of varicose veins. The results of this procedure in view of perioperative complications are very good, with the incidence of perioperative deep venous thrombosis varying between 0.05% and 0.1%. Recurrence rates between 6% and 60% are published. However, the true recurrence rate is unknown since an exact definition of recurrent varicosis is still lacking. In recurrent varices it is essential to distinguish between disease progression, including neorevascularisation, and technical errors. Endovascular procedures for elimination of the superficial venous system – radiofrequency obliteration and endovenous laser therapy – meanwhile have established themselves as alternative, minimally invasive procedures. The perioperative complication rate of endovenous procedures is very low and comparable to that of the classic operation. Good results, with occlusion rates of the treated vein around 87% to 93% up to 2 years postoperatively, have been published for both endovenous laser therapy and radiofrequency obliteration. For the latter, 5-year results were published, with occlusion of the treated vein in 87%. Results in the literature for radiofrequency are better documented than for endovenous laser treatment because there are now five prospective randomised trials for the former and most publications for endovenous laser treatment are single-center experiences. The advantage of endovenous procedures, especially radiofrequency obliteration, over the classic operation is the lower rate of perioperative pain and better quality of life. The spectrum of operative treatment methods of the superficial venous system has increased tremendously due to new technical developments. For the surgeon this implies the necessity of informing patients conscientiously about the pros and cons and available results of each procedure, and carefully weighing which methods are at the time best for the patient.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6

Literatur

  1. Agus GB, Mancini S, Magi G (2006) The first 1000 cases of Italian Endovenous-laser Working Group (IEWG). Rationale and long-term outcomes for the 1999–2003 period. Int Angiol 25: 209–215

    PubMed  CAS  Google Scholar 

  2. Babcock WW (1907) A new operation for the exstirpation of varicose veins of the leg. New York Med J 86: 153–156

    Google Scholar 

  3. Balzer K (2001) Komplikationen bei Varizenoperationen. Zentralbl Chir 126: 537–542

    Article  PubMed  CAS  Google Scholar 

  4. Belcaro G, Nicolaides AN, Ricci A et al. (2000) Endovascular sclerotherapy, surgery and surgery plus sclerotherapy in superficial venous incompetence: A randomised, 10-year follow-up trial – final results. Angiology 51: 529–534

    Article  PubMed  CAS  Google Scholar 

  5. Bush RG, Sitamma HN, Hammond KA (2005) 940-nm Laser for treatment of saphenous insufficiency: Histological analysis and long-term follow-up. Photomed Laser Surg 23: 15–19

    Article  PubMed  Google Scholar 

  6. Chang CJ, Chua JJ (2002) Endovenous laser photocuagulation (EVLP) for varicose veins. Lasers Surg Med 31: 257–262

    Article  PubMed  Google Scholar 

  7. Disselhoff BCVM, derKinderen DJ, Moll FL (2005) Is there recanalization of the great saphenous vein 2 years after endovenous laser treatment. J Endovasc Ther 731–738

  8. Dolle JP, Rezvan A, Allen FD et al. (2005) Nerve growth factor-induced migration of endothelial cells. J Pharmacol Exp Ther 315: 1220–1227

    Article  PubMed  CAS  Google Scholar 

  9. Durkin MT, Turton EP, Wijesinghe LD et al. (2001) Long saphenous vein stripping and quality of life – a randomized trial. Eur J Vasc Endovasc Surg 21: 545–549

    Article  PubMed  CAS  Google Scholar 

  10. Dwerryhouse S, Davies B, Harradine K, Earnshaw J (1999) Stripping the long saphenous vein reduces the rate of reoperation for recurrent varicose veins: five-year results of a randomised trial. J Vasc Surg 29: 589–592

    Article  PubMed  CAS  Google Scholar 

  11. Einarsson E, Eklöf B, Neglén P (1993) Sclerotherapy or surgery as treatment for varicose veins: a prospective randomized study. Phlebology 8: 22–26

    Google Scholar 

  12. Fischer R, Linde N, Duff C (2001) Cure and reappearance of symptoms of varicose veins after stripping operation – a 34 year follow-up. JP 1: 49–60

    Google Scholar 

  13. Fischer R, Linde N, Duff C et al. (2001) Late recurrent saphenofemoral junction reflux after ligation and stripping of greater saphenous vein. J Vasc Surg 34: 236–240

    Article  PubMed  CAS  Google Scholar 

  14. Gerard JL, Desgranges P, Cequemin JP et al. (2002) Feasibility of ambulatory endovenous laser for the treatment of greater saphenous varicose veins: One-month outcome in a series of 20 outpatients. J Mal Vasc 27: 222–225

    PubMed  CAS  Google Scholar 

  15. Goldmann MP, Mauricio M, Rao J (2004) Intravascular 1320 nm laser closure of the great saphenous vein: A 6- to 12-month follow up study. Dermatol Surg 30: 1380–1385

    Article  Google Scholar 

  16. Hach W (2000) Die Entwicklung der großen Venenchirurgie in Europa. Chirurg 71: 337–341

    PubMed  CAS  Google Scholar 

  17. Hach W, Hach-Wunderle V (Hrsg) (1995) Die Rezirkulationskreise der primären Varikose. Springer, Berlin Heidelberg NewYork London Paris; ISBN 3–540–58411–0

  18. Helmig L (1983) Häufigkeit von Frühkomplikationen bei 13.024 Krampfaderoperationen. Phlebol Proktol 12: 184–195

    Google Scholar 

  19. Hingorani AP, Ascher E, Markevich N et al. (2004) Deep venous thrombosis after radiofrequency ablation of greater saphenous vein: a word of caution. J Vasc Surg 40: 500–504

    Article  PubMed  Google Scholar 

  20. Huang Y, Jiang M, Li W et al. (2005) Endovenous laser treatment combined with a surgical strategy for treatment of venous insufficiency in lower extremity: A report of 208 cases. J Vasc Surg 42: 494–501

    Article  PubMed  Google Scholar 

  21. Kabnick LS (2006) Outcome of different endovenous laser wavelengths for great saphenous vein ablation. J Vasc Surg 43: 88–93

    Article  PubMed  Google Scholar 

  22. Kim HS, Nwankwo IJ, Hong K, Moelgunn SJ (2006) Lower energy endovenous laser ablation of the great saphenous vein with 980 nm diode laser in continuous mode. Cardiovasc Intervent Radiol 29: 64–69

    Article  PubMed  Google Scholar 

  23. Labropoulos N, Bhatti A, Leon L et al. (2006) Neovascularisation after great saphenous vein ablation. Eur J Vasc Endovasc Surg 31: 219–222

    Article  PubMed  CAS  Google Scholar 

  24. Lahl W, Jelonek M, Nagel T (2004) Thermometrische Untersuchungen zur paravasalen Temperatur während endovenöser Lasertherapie der Varikosis. Phlebologie 33: A11

    Google Scholar 

  25. Lurie F, Creton D, Eklof B et al. (2003) Prospective randomized study of endovenous radiofrequency obliteration (closure procedure) versus ligation and stripping in a selected patient population (EVOLVeS Study) J Vasc Surg 38: 207–214

    Google Scholar 

  26. Lurie F, Creton D, Eklof B et al. (2005) Prospective randomised study of endovenous radiofrequency obliteration (closure) versus ligation and vein stripping (EVOLVeS): two-year follow-up. Eur J Vasc Endovasc Surg 29: 67–73

    Article  PubMed  CAS  Google Scholar 

  27. MacKenzie RK, Paisley A, Allan PL, Lee AJ (2002) The effect of long saphenous vein stripping on quality of life. J Vasc Surg 35: 1197–1203

    Article  PubMed  CAS  Google Scholar 

  28. McMullin GM, Coleridge-Smith PD, Scurr JH (1991) Objective assessment of high ligation without stripping the long saphenous vein. Br J Surg 78: 1139–1142

    Article  PubMed  CAS  Google Scholar 

  29. Marston WA, Owens LV, Davies S et al. (2006) Endovenous saphenous ablation corrects the hemodynamic abnormality in patients with CEAP clinic class 3–6 CVI due to superficial reflux. J Vasc Endovasc Surg 40: 125–130

    Article  Google Scholar 

  30. Mekako AI, Hatfield J, Bryce J et al. (2006) A nonrandomized controlled trial of endovenous laser therapy and surgery in the treatment of varicose veins. Ann Vasc Surg 20: 452–457

    Article  Google Scholar 

  31. Merchant RF, DePalma RG, Kabnick LS (2002) Endovascular obliteration of saphenous reflux: a multi-center study. J Vasc Surg 35: 1190–1196

    Article  PubMed  Google Scholar 

  32. Merchant RF, Pichot O (2005) Long-term outcomes of endovenous radiofrequency obliteration of saphenous reflux as a treatment for superficial venous insufficency. J Vasc Surg 42: 502–509

    Article  PubMed  Google Scholar 

  33. Min RJ, Zimmet SE, Isaacs MN, Forrestal MD (2001) Endovenous laser treatment of the incompetent greater saphenous vein. J Vasc Interv Radiol 12: 1167–1171

    Article  PubMed  CAS  Google Scholar 

  34. Min RJ, Khilneni NM (2005) Endovenous laser ablation of varicose veins. J Cardiovasc Surg 46: 395–405

    CAS  Google Scholar 

  35. Morrison N (2005) Saphenous Ablation: What are the choises, Laser or RF Energy. Sem Vasc Surg 18: 15–18

    Article  Google Scholar 

  36. Mumme A, Olbrich S, Barbera L, Stücker M (2002) Saphenofemorale groin recurrence following stripping of the long saphenous vein: technical error or neovascularization? Phlebologie 31: 38–41

    Google Scholar 

  37. Munn SR, Morton JB, Macbeth WA, Mcleish AR (1981) To strip or not to strip the long saphenous vein? A varicose veins trial. Brit J Surg 68: 426–428

    Article  PubMed  CAS  Google Scholar 

  38. Navarro L, Min RJ, Bone C (2001) Endovenous laser: a new minimally invasive method of treatment for varicose veins – preliminary observations using a n 810 nm diode laser. Dermatol Surg 27: 117–122

    Article  PubMed  CAS  Google Scholar 

  39. Noppeney T, Kluess HG, Gerlach H et al. (2004) Leitlinie zur Diagnostik und Therapie des Krampfaderleidens. Gefässchirurgie 9: 290–308

    Article  Google Scholar 

  40. Noppeney T, Eckstein HH, Niedermeier H et al. (2005) Ergebnisse des Qualitätssicherungsprojektes Varizenchirurgie der Deutschen Gesellschaft für Gefäßchirurgie. Gefässchirurgie 4: 121–128

    Article  Google Scholar 

  41. Noppeney T, Nüllen H (2005) Die Rezidivvarikose – was ist das? Gefässchirurgie 10: 424–427

    Article  Google Scholar 

  42. Nüllen H, Rheese van Ohlen C (1995) Ambulante Varizenchirurgie in der Praxis. In: Ihmig H, Schröder A (Hrsg) Varizen, Popliteaaneurysmen. Steinkopff-Verlag, Darmstadt, S 73–80

  43. Nyamekye I, Shephard NA, Davies B et al. (1998) Clinicopathological evidence that neovascularisation is a cause of recurrent varicose veins. Eur J Vasc Surg 15: 412–415

    Article  CAS  Google Scholar 

  44. Oh CK, Jung DS, Jang HS, Kwon KS (2003) Endovenous laser surgery of the incompetent greater saphenous vein wirh a 980 nm diode laser. Dermatol Surg 29: 1135–1140

    Article  PubMed  Google Scholar 

  45. Peräla J, Rautio T, Blancari F et al. (2005) Radiofrequency endovenous obliteration versus stripping of the long saphenous vein in the management of primary varicose veins: 3-year outcome of a randomized study. Ann Vasc Surg 19: 669–672

    Article  PubMed  Google Scholar 

  46. Perkowski P, Ravi R, Gowda RC et al. (2004) Endovenous laser ablation of the saphenous vein fort treatment of venous insufficiency and varicose veins: early results from a large single-center experience. J Endovasc Ther 11: 132–138

    Article  PubMed  Google Scholar 

  47. Perrin M, Guex JJ, Ruckley CV et al. (2000) Recurrent Varices after Surgery (REVAS), a Consensus Document. Cardiovasc Surg 8: 233–245

    Article  PubMed  CAS  Google Scholar 

  48. Perrin M (2004) Endoluminal treatment of lower limb varicose veins by endovenous laser and radiofrequency techniques. Phlebology 19: 70–178

    Article  Google Scholar 

  49. Petronelli S, Prudenzano R, Mariano L, Violante F (2006) Endovenous laser therapy of the incompetent great saphenous vein. Radio Med (Torino) 111: 85–92

    Google Scholar 

  50. Pichot O, Kabnick LS, Creton D et al. (2004) Duplex ultrasound scan findings two years after great saphenous vein radiofrequency endovenous obliteration; J Vasc Surg 39: 189–195

    Google Scholar 

  51. Proebstle TM, Gül D, Leht HA et al. (2002) Infrequent early recanalization of greater saphenous vein after endovenous laser treatment. J Vasc Surg 38: 511–516

    Article  Google Scholar 

  52. Proebstle TM, Gül D, Kargl A, Knop J (2003) Endovenous laser treatment of the lesser saphenous vein with a 940-nm diode laser: early results. Dermatol Surg 29: 357–361

    Article  PubMed  Google Scholar 

  53. Proebstle TM (2004) Endoluminale Lasertherapie mit dem 940 nm Laser – Laserchirurgie und Effizienz der Methode. Phlebologie 33: A12

    Google Scholar 

  54. Proebstle TM, Moehler T, Gül D, Herdemann S (2005) Endovenous treatment of the great saphenous vein using a 1.340 nm Nd: YAG Laser causes fewer side effects than using a 940 nm diode Laser. Dermatol Surg 31: 1678–1683

    Article  PubMed  CAS  Google Scholar 

  55. Proebstle TM, Vago B, Alm J et al. (2007) Treatment of the incompetent great saphenous vein by radiofrequency segmental endovenous ablation (RSTA): First clinical experience. J Vasc Surg (in press)

  56. Puggioni A, Kalra M, Carmo M et al. (2005) Endovenous laser therapy and radiofrequency ablation of the great saphenous vein: Analysis of early efficacy and complications. J Vasc Surg 42: 488–493

    Article  PubMed  Google Scholar 

  57. Rautio T, Ohtnmaa A, Peräla J et al. (2002) Endovenous obliteration versus conventional stripping operation in the treatment of primary varicose veins: a randomized controlled trail with comparison of the costs. J Vasc Surg 35: 958–965

    Article  PubMed  Google Scholar 

  58. Ravi R, Rodriguez-Lopez JA, Trayler EA et al. (2006) Endovenous ablation of incometent saphenous veins: a large single-center experience. J Endovasc Ther 13: 244–248

    Article  PubMed  Google Scholar 

  59. vanRij AM et al. (2004) Neovascularisation and recurrent varicose veins: more histologic and ultrasound evidence. J Vasc Surg 40: 296–302

    Article  Google Scholar 

  60. Rutgers PH, Kitslar P (1994) Randomized trial of stripping versus high ligation combined with sclerotherapy in the treatment of the incompetent greater saphenous vein. Am J Surg 168: 311–315

    Article  PubMed  CAS  Google Scholar 

  61. Sadick NS, Wasser S (2004) Combined endovascular laser with ambulatory phlebectomyfor the treatment of superficial venous incometence: a 2 year perspective. J Cosmet Laser Ther 6: 44–49

    Article  PubMed  Google Scholar 

  62. Sharif MA, Soong CV, Lau LL et al. (2006) Endovenous laser treatment for long saphenous vein incompetence. Br J Surg 93: 831–835

    Article  PubMed  CAS  Google Scholar 

  63. Siani A, Flaishman I, Rossi A et al. (2006) Indications and results of endovenous laser treatment (EVLT) for greater saphenous vein incompetence. Our experience. Minerva Cardioangiol 54: 369–376

    PubMed  CAS  Google Scholar 

  64. Schmedt CG (2006) Investigation on radiofrequency and laser 980 nm, effects after endoluminal treatment of saphenous insufficiency in an ex vivo model. Eur J Vasc Endovasc Surg 32: 318–325

    Article  PubMed  Google Scholar 

  65. Schmedt CG, Steckmeier BM (2006) Endoluminale Radiofrequenz und Lasertherapie zur Therapie der Stammveneninsuffizienz. In: Marshall/Breu (Hrsg) Handbuch der Angiologie. 15. Erg.-Lfg. 12

  66. Timperman PE, Sichlau M, Ryu RK (2004) Greater energy delivery improves treatment success of endovenous laser treatment of incompetent veins. J Vasc Interv Radiol 15: 1061–1063

    PubMed  Google Scholar 

  67. Turton EP, Scott DJ, Richards SP et al. (1999) Duplex-derived evidence of reflux after varicose vein surgery: neoreflux or neovascularisation? Eur J Vasc Endovasc Surg 17: 230–233

    Article  PubMed  CAS  Google Scholar 

  68. Weiss RA (2002) Comparison of endovenous radiofrequency versus 810 nm diode laser occlusion of large veins in an animal mode. Dermatol Surg 28: 56–61

    Article  PubMed  Google Scholar 

  69. Chant ADB, Jones HO, Wedell JM (1972) Varicose veins: a comparison of surgery and injection/compression sclerotherapy. Lancet 2:1188-1191

    Article  PubMed  CAS  Google Scholar 

  70. Hobbs JT (1974) Surgery and sclerotherapy in the treatment of varicose veins. Arch Surg 190:793-796

    Google Scholar 

  71. Hobbs JT (1984) Surgery or sclerotherapy for varicose veins: 10 year results of a random study. In: Tesi M, Dormandy J (eds). Superficial and deep venous diseases of the lower limbs. Edizioni Minerva Medica, Turin 243-246

  72. Jakobson HB (1979) The value of different forms of treatment for varicose veins. Br J Surg 66:72-76

    Google Scholar 

  73. Noppeney T, Noppeney J, Kurth I (2002) Ergebnisse nach klassischer Varizenchirurgie. Zentralbl Chir 127:748-751

    Article  PubMed  CAS  Google Scholar 

Download references

Interessenkonflikt

Keine Angaben

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to T. Noppeney.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Noppeney, T., Rewerk, S., Winkler, M. et al. Primäre Varikose. Chirurg 78, 620–629 (2007). https://doi.org/10.1007/s00104-007-1366-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00104-007-1366-9

Schlüsselwörter

Keywords

Navigation