Zusammenfassung
Die Entscheidung zu operativen Eingriffen in der Schwangerschaft sollte wegen der Gefahr für Mutter und Kind nach Möglichkeit interdisziplinär unter Koordination durch die Geburtshilfe vorgenommen werden. Hierbei müssen die Risiken des operativen Eingriffes für die Mutter und den Fetus kalkuliert und gegen die Nachteile einer nicht operativen Therapie abgewogen werden. Sollte keine vitale Bedrohung für die Mutter vorliegt, besitzt die Entwicklung des Fetus höchste Priorität bei therapeutischen Überlegungen. Die größte Gefährdung des Fetus besteht im 1. Schwangerschaftstrimenon. Operationen mit aufgeschobener Dringlichkeit sollten daher, sofern sie nicht bis nach der Gravidität verschoben werden können, möglichst nicht in den ersten 3, sondern zwischen dem 4. und 6. Schwangerschaftsmonat ausgeführt werden. Wenn maternal nötig, müssen operative Eingriffe aber zu jedem Zeitpunkt in der Gravidität ausgeführt werden. Ab Erreichen der extrauterinen Lebensfähigkeit (ca. 24./25. Schwangerschaftswoche) ist dabei in Abwägung zwischen maternaler Gefährdung und kindlicher Morbidität und Mortalität immer zwischen jeweiliger operativer Option inklusive vorzeitiger Entbindung oder postoperativer Fortführung der Schwangerschaft zu wählen. Vor dem Hintergrund der potenziellen Frühgeburtlichkeit sollten operative Eingriffe in der Schwangerschaft nur an perinatologischen Zentren mit neonatologischer Intensivstation vorgenommen werden.
Abstract
The decision for surgical intervention during pregnancy should be interdisciplinary and include all aspects of prenatal care. The risk of surgery to mother and fetus must be calculated and weighed against the disadvantages of other, nonradical methods. If there is no danger to the mother, the highest priority in all therapeutic considerations is the fetus and its development. The greatest threat to the fetus exists during the first trimester. In case surgery cannot be postponed till after birth, they should be done if possible during the 4th to 6th months of pregnancy, not the first trimester. In case of danger to the mother, necessary surgery must be performed any time during the pregnancy. Once extrauterine fetal survival is possible (the 24th or 25th week of pregnancy), danger to the mother and the child’s mortality and morbidity of the various options must be carefully weighed for both premature delivery and continued pregnancy. Due to the problems of prematurity, any surgery during pregnancy should be carried out only in perinatal clinics outfitted with neonatologic intensive care units.
Literatur
Affleck DG, Hanrahan DL, Egger MJ, Price RR (1999) The laparoscopic management of appencitis and cholelithiasis during pregnancy. Am J Surg 178: 523–529
Aishima M, Tanaka M, Haraoka M, Naito S (2000) Retroperitoneal laparoscopic adrenalectomy in pregnant women with Cushing‘s syndrome. J Urol 164: 770–771
Allen JR, Helling TS, Langenfeld M (1989) Intraabdominal surgery during pregnancy. Am J Surg 158: 567–569
Amos JD, Schorr SJ, Norman PF et al. (1996) Laparoscopic surgery during pregnancy. Am J Surg 171: 435–437
Anderson B, Nielson TF (1999) Appendicitis in pregnancy: diagnosis, management and complications. Acta Obstet Scand 78: 758–762
Andersson REB, Lambe M (2001) Incidence of appendicitis during pregnancy. Int J Epidemiol 30: 1281–1285
Antonelli NM, Dotters DJ, Katz VL et al. (1996) Cancer in pregnancy: a review of the literature. Part I–II. Obstet Gynecol Surv 51: 125–142
Auabara S, Gross GWW, Sirinek K (1997) Laparoscopic cholecystectomy during pregnancy is safe for both mother and fetus. J Gastrointest Surg 1: 48–52
Barone JE, Bears S, Chen S et al. (1999) Outcome study of cholecystectomy during pregnancy. Am J Surg 177: 232–236
Bernstein MA, Madoff RD, Caushaj PF (1993) Colon and rectal cancer in pregnancy. Dis Colon Rectum 36: 172–178
Bisharah M, Tulandi T (2003) Laparoscopic surgery in pregnancy. Clin Obstet Gynecol 46: 92–97
Catlin EA, Roberts JD, Erana R et al. (1999) Transplacental transmission of natural-killer-cell lymphoma. N Engl J Med 341: 85–91
Cosenza CA, Saffari B, Jabbour N et al. (1999) Surgical management of biliary gallstone disease during pregnancy. Am J Surg 178: 545–548
Curet MJ, Allen D, Josloff RK et al. (1996) Laparoscopy during pregnancy. Arch Surg 31: 546–551
Daradkeh S, Sumrein I, Daoud F et al. (1999) Management of gallbladder stones during pregnancy: conservative treatment or laparoscopic? Hepato-Gastroenterol 46: 3074–3076
Dildy GA, Moise KJ, Carpenter RJ et al. (1989) Maternal malignancy metastatic to the products of conception. Obstet Gynecol Surv 44: 535–540
Doberneck RC (1995) Appendectomy during pregnancy. Am Surg 51: 265–268
Friedreich N (1866) Beiträge zur Pathologie des Krebses. Virchows Arch (Pathol Anat) 36: 465
Glasgow RE, Visser BC, Harris HW et al. (1998) Changing management of gallstone disease in pregnancy. Surg Endosc 12: 241–246
Gurbuz AT, Peetz ME (1997) The acute abdomen in the pregnant patient. Is there a role for laparoscopy? Surg Endosc 11: 98–102
Hee P, Viktrup L (1999) The diagnosis of appendicitis during pregnancy and maternal and fetal outcome after appendectomy. Int J Gynecol Obstet 65: 129–135
Hertel H, Possover M, Kuhne-Heid R, Schneider A (2001) Laparoscopic lymph node staging of cervical cancer in the 19th week of pregnancy: a case report. Surg Endosc 15: 324
Heres P, Wiltink J, Cuesta MA et al. (1993) Colon carcinoma durino pregnancy: a lethal coincidence. Eur J Obstet Gynecol Reprod Biol 48: 149–152
Hohenberger W, Beckmann MW, Horch RE (2005) Chirurgische Notfälle in der Schwangerschaft. CHAZ 6: 169–175
Holthausen UH, Mettler L, Troidl H (1999) Pregnancy: a contraindication? World J Surg 23: 856–862
Hunter JG (1992) 1991 scientific session and postgraduate course: advances in laparoscopic general surgery. Surg Endosc 6: 47–56
Hunter JG, Swanstrom L, Thornburg K (1995) Carbon dioxide pneumoperitoneum induces fetal acidosis in a pregnant ewe model. Surg Endosc 9: 272–279
Iwase K, Higaki J, Yoon HF et al. (2001) Hand assisted laparoscopic splenectomy for idiopathic thrombocytopenic purpura during pregnancy. Surg Laparosc Endosc Percutan Tech 11: 53–56
Kort B, Katz VL, Watson WJ (1993) The effect of nonobstetric operation during pregnancy. Surg Gynecol Obstet 177: 371–376
KuhlmannRS, Cruishank DP (1994) Maternal trauma during pregnancy. Clin Obstet Gynecol 37: 274–293
Lim HK, Bae SH, Seo GS (1992) Diagnosis of acute appendicitis in pregnant woman: value of sonography. Am J Roentgenol 159: 539–542
Martin C, Varner MW (1994) Physiological changes in pregnancy: surgical implications. Clin Obstet Gynecol 37: 241–255
Maslovitz S, Gutman G, Lessing JB, Kupferminc MJ, Gamzu R (2003) The significance of clinical signs and blood indices for the diagnosis of appendicitis during pregnancy. Gynecol Obstet Invest 56: 188–191
Mourad J, Elliott JP, Erickson L, Lisboa L (2000) Appendicitis in pregnancy: new information that contradicts long-held clinical beliefs. Am J Obstet Gynecol 182: 1027–1029
Al Mulhim AA (1996) Acute appendicitis in pregnancy: a review of 52 cases. Int Surg 81: 295–297
Nesbitt TH, Kay HH, McCoy MC et al. (1996) Endoscopic management of biliary disease during pregnancy. Obstet Gynecol 87: 806
Oto A, Ernst RD, Shah R et al. (2005) Right lower quadrant pain and suspected appendicitis in pregnant woman: evaluation with MR Imaging–initial experience. Radiology 234: 445–451
Pavlidis NA (2002) Coexistence of pregnancy and malignancy. The Oncologist 7: 279–287
Perdue PW, Johnson HW, Stafford PW (1992) Intestinal obstruction complicating pregnancy. Am J Surg 164: 384–388
Poole GV, Martin JN, Perry et al. (1996) Trauma in pregnancy. The role of interpersonal violence. Am J Obstet Gynecol 174: 1502–1510
Reedy MB, Kallen B, Kuehl TJ (1997) Laparoscopy during pregnancy: a study of five fetal outcome parameters with use of the Swedish Health Registry. Am J Obstet Gynecol 177: 673–679
Rollins MD, Chan KJ, Price RR (2004) Laparoscopy for appendicitis and cholelithiasis during pregnancy. Surg Endosc 18: 237–241
Stone K (2002) Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol 45: 553–561
Sharp HT (2002) The acute abdomen during pregnancy. Clin Obstet Gynecol 45: 405–413
Sivyer P (2000) Pelvic ultrasound in women. World J Surg 24: 188–197
Tamir IL, Bongard FS, Klein SR (1990) Acute appendicitis in the pregnant patient. Am J Surg 160: 571–576
To WW, Ngai CS, Ma HK (1995) Pregnancies complicated by acute appendicitis. Aust NZ J Surg 656: 799–803
Ueberrueck T, Koch A, Meyer L, Hinkel M, Gastinger I (2004) Ninety-four appendectomies for suspected acute appendicitis during pregnancy. World J Surg 28: 508–511
Visser BC, Glasgow RE, Mulvihill KK, Mulvihill SJ (2001) Safety and timing of nonobstetric abdominal surgery in pregnancy. Dig Surg 18: 409–417
Wagner LK, Huda W (2004) When a pregnant woman with suspected appendicitis is referred for a CT scan, what should a radiologist do to minimize potential radiation risks? Pediatr Radiol 34: 589–590
Walsh C, Fazio VW (1998) Cancer of the colon, rectum, and anus arising during pregnancy. The surgeon‘s perspective. Gastroenterol Clin North Am 27: 257–267
Weingold AB (1983) Appendicitis in pregnancy. Clin Obstet Gynecol 26: 801–809
Woods JB, Martin NM, Ingram FH et al (1992) Pregnancy complicated by carcinoma of the colon above the rectum. Am J Perinatol 9: 102–110
Interessenkonflikt:
Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lang, H., Lang, U. Chirurgie in der Schwangerschaft. Chirurg 76, 744–752 (2005). https://doi.org/10.1007/s00104-005-1075-1
Issue Date:
DOI: https://doi.org/10.1007/s00104-005-1075-1