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Aktuelle Daten und Trends zu Methicillin-resistenten Staphylococcus aureus (MRSA)

Current data and trends on methicillin-resistant Staphylococcus aureus (MRSA)

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Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

Zusammenfassung

Methicillin-resistente Staphylococcus aureus (MRSA) gehören weltweit zu den häufigsten Erregern nosokomialer Infektionen. Am Nationalen Referenzzentrum (NRZ) für Staphylokokken wird stetig eine repräsentative Anzahl an Isolaten aus deutschen Krankenhäusern und anderen medizinischen Einrichtungen analysiert, um die Dynamik des Auftretens und der Verbreitung von MRSA-Klonen zu verfolgen. Gemäß den vom NRZ vorgegebenen Kriterien für die Einsendung, werden vor allem Isolate aus einem gehäuften Auftreten von Infektionen sowie aus schweren Infektionsverläufen eingesandt. Der vorliegende Beitrag befasst sich mit aktuellen Daten aus dem NRZ für Staphylokokken zu Antibiotikaresistenzen und MRSA-Epidemiestämmen krankenhausassoziierter Infektionen. Weiterhin werden Ergebnisse zu Community-assoziierten MRSA, die außerhalb medizinischer Einrichtungen auftreten, und zu MRSA aus zoonotischen Reservoiren vorgestellt und diskutiert.

Abstract

Nosocomial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a problem in hospital settings worldwide. The National Reference Centre for Staphylococci performs molecular typing on a representative sample set of MRSA isolates from German hospitals for assessing long-term trends thus following the dynamics of emergence and spread of MRSA clones. The article focuses on recent data concerning antibiotic resistance and epidemic MRSA in nosocomial settings and also reflects the impact of community-acquired MRSA and MRSA from zoonotic reservoirs. Identifying common and newly emerging clones is an on-going challenge in the changing epidemiology of MRSA and prevention of further spread needs molecular surveillance.

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Authors and Affiliations

  1. Nationales Referenzzentrum für Staphylokokken und Enterokokken, Robert Koch-Institut, Burgstr. 37, 38855, Wernigerode, Deutschland

    F. Layer, C. Cuny, B. Strommenger, G. Werner & W. Witte

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  1. F. Layer
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  2. C. Cuny
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  3. B. Strommenger
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  4. G. Werner
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  5. W. Witte
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Correspondence to F. Layer.

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Layer, F., Cuny, C., Strommenger, B. et al. Aktuelle Daten und Trends zu Methicillin-resistenten Staphylococcus aureus (MRSA). Bundesgesundheitsbl. 55, 1377–1386 (2012). https://doi.org/10.1007/s00103-012-1560-x

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  • DOI: https://doi.org/10.1007/s00103-012-1560-x

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