Stellungnahme der ZKBS zur Risikobewertung des rekombinanten Vacciniavirus MVA

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  1. Meyer H, Sutter G, Mayr A (1991) Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence.J Gen Virol 72:1031–1038PubMedCrossRefGoogle Scholar
  2. Sutter G, Ramsey-Ewing A, Rosales R, Moss B (1994) Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant.J Virol 68:4109–4116PubMedCentralPubMedGoogle Scholar
  3. Carroll MW, Moss B (1997) Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line. Virology 238:198–211PubMedCrossRefGoogle Scholar
  4. Drexler I, Heller KB, Wahren B, Erfle V, Sutter G (1998) Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation,but not in various human transformed and primary cells.J Gen Virol 79:347–352PubMedGoogle Scholar
  5. Wyatt LS, Miles W, Carroll MW, Czerny CP, Merchlinsky M, Sisler JR, Moss B (1998) Marker rescue of the host range restriction defects of modified vaccinia virus Ankara. Virology 251:334–342PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2002

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