Skip to main content

Einfluss der medikamentösen Prämedikation auf die präoperative Angstreduktion: eine multizentrische prospektive Beobachtungsstudie – IMPACT

Impact of premedication on anxiety: a multi-centre, prospective observational cohort study

This is a preview of subscription content, access via your institution.

Abb. 1
Abb. 2


  1. Kiecolt-Glaser JK, Page GG, Marucha PT, MacCallum RC, Glaser R (1998) Psychological influences on surgical recovery. Perspectives from psychoneuroimmunology. Am Psychol 53(11):1209–1218

    Article  CAS  Google Scholar 

  2. Van Grootven B, Detroyer E, Devriendt E et al (2016) Is preoperative state anxiety a risk factor for postoperative delirium among elderly hip fracture patients? Geriatr Gerontol Int 16(8):948–955

    Article  Google Scholar 

  3. Kowark A, Rossaint R, Keszei AP, Bischoff P, Czaplik M, Drexler B et al (2019) Impact of PReOperative Midazolam on OuTcome of Elderly patients (I-PROMOTE): study protocol for a multicentre randomised controlled trial. Trials. 20(1):430.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Aldecoa C, Bettelli G, Bilotta F et al (2017) European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium. Eur J Anaesthesiol 34(4):192–214

    Article  Google Scholar 

  5. Maurice-Szamburski A, Auquier P, Viarre-Oreal V et al (2015) Effect of sedative premedication on patient experience after general anesthesia: a randomized clinical trial. JAMA 313(9):916–925

    Article  CAS  Google Scholar 

  6. Walker KJ, Smith AF (2009) Premedication for anxiety in adult day surgery. Cochrane Database Syst Rev.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Saller T, von Dossow K, Hofmann-Kiefer K et al (2006) Online-Umfrage zur Praxis der Prämedikation in Deutschland. Anästh Intensivmed 57:S560

    Google Scholar 

  8. Berth H, Petrowski K, Balck F (2007) The Amsterdam Preoperative Anxiety and Information Scale (APAIS)—the first trial of a German version. Psychosoc Med 4:Doc01

    PubMed  PubMed Central  Google Scholar 

  9. Kowark A, Adam C, Ahrens J et al (2018) Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia. BMJ Open 8(10):e23609

    Article  Google Scholar 

  10. Coburn M, Sanders RD, Maze M et al (2018) The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial. Br J Anaesth 120:127–137

    Article  CAS  Google Scholar 

  11. Kowark A, Rossaint R, Pühringer F, Keszei AP, Fritz H, Fröba G, Rex C, Haas H, Otto V, Coburn M, Study Collaborators (2018) Emergence times and airway reactions during general anaesthesia with remifentanil and a laryngeal mask airway: a multicentre randomised controlled trial. Eur J Anaesthesiol 35(8):588–597

    Article  CAS  Google Scholar 

  12. Peri-interventional outcome study in the elderly. Accessed 28th February 2020

Download references

Author information

Authors and Affiliations



Corresponding author

Correspondence to A. Kowark.

Ethics declarations


A. Kowark gibt an, dass sie Studienteilnehmerin der IMPACT-Studie ist.

Additional information

Eine vollständige Liste aller an der Studie Beteiligten finden Sie als elektronisches Zusatzmaterial (Siehe Box).

Caption Electronic Supplementary Material

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Kowark, A., Studiengruppe IMPACT. Einfluss der medikamentösen Prämedikation auf die präoperative Angstreduktion: eine multizentrische prospektive Beobachtungsstudie – IMPACT. Anaesthesist 69, 679–682 (2020).

Download citation

  • Published:

  • Issue Date:

  • DOI: