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Listeriensepsis mit Leitsymptom Delir

Sepsis masquerading as delirium

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Zusammenfassung

Ein bis dato gesunder 60-Jähriger kam mit heftigsten Kopfschmerzen, Wesensänderung und Fieber in die Notaufnahme – Verdachtsdiagnose bakterielle Meningitis mit Alkoholentzugsdelir. Unter der Behandlung auf der Normalstation entwickelte er ein ausgeprägtes Delir und eine Tachypnoe. Die Verdachtsdiagnose „schwere Sepsis“ erfolgte erst durch den Intensivmediziner. Die Blutkultur wies Listerien auf. Bei Patienten mit „Delir“ oder anderen akuten Wesensveränderungen und Anzeichen für eine Infektion sollte stets eine Sepsis als Ursache ausgeschlossen bzw. ohne Zeitverzug eine Sepsistherapie eingeleitet werden.

Abstract

A previously healthy 60-year-old patient presented to the emergency department with severe headache, altered personality and fever. He was treated for bacterial meningitis with delirium of unknown cause but presumed to be due to alcohol withdrawal. Despite receiving the antibiotic therapy regimen recommended for bacterial meningitis the patient’s condition rapidly deteriorated with profound delirium and tachypnea. The intensivist who was consulted immediately suspected sepsis-associated organ failure and admitted the patient to the intensive care unit (ICU). The blood culture was positive for Listeria. After 10 days the patient could be discharged from the ICU and ultimately recovered completely. In patients presenting with unexplained delirium or altered personality the suspicion of septic encephalopathy should always be considered. They should be admitted to the ICU and sepsis treatment should be initiated without delay.

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Correspondence to K. Reinhart ML.

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Interessenkonflikt

A. Seifert, C. S. Hartog, J. Zweigner, W. Schummer und K. Reinhart geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben.

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Seifert, A., Hartog, C.S., Zweigner, J. et al. Listeriensepsis mit Leitsymptom Delir. Anaesthesist 66, 858–861 (2017). https://doi.org/10.1007/s00101-017-0361-x

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  • DOI: https://doi.org/10.1007/s00101-017-0361-x

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