Zusammenfassung
Es wird über die erfolgreiche Anwendung des C1-Esterase-Inhibitors (C1-INH) bei „capillary leak syndrome“ berichtet. Die Koinzidenz von Latexexposition und Einnahme eines „Angiotensin-converting-enzyme“(ACE)-Hemmers führte bei dem Patienten zum protrahierten Schock mit Multiorganversagen. Der therapeutische Erfolg trat trotz leitliniengerechter Therapie erst nach Applikation von 1500 IE C1-INH ein.
Abstract
This article reports the successful use of C1 esterase inhibitor in the treatment of capillary leak syndrome. The coincidence of exposure to latex during surgery and medication with ramipril led to prolonged shock complicated by secondary hyperfibrinolysis, capillary leak syndrome and multiple organ failure. Initial treatment according to relevant guidelines failed to stabilize the condition. Treatment was only successful after administration of 1,500 IU of human C1 esterase inhibitor.
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Seidel, R. Erfolgreiche Anwendung von C1-Esterase-Inhibitor bei „capillary leak syndrome“. Anaesthesist 61, 954–957 (2012). https://doi.org/10.1007/s00101-012-2092-3
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DOI: https://doi.org/10.1007/s00101-012-2092-3