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Naloxoninduziertes Lungenödem

Fallbericht mit Literaturübersicht und kritischer Bewertung

Naloxone-induced pulmonary edema

Case report with review of the literature and critical evaluation

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Zusammenfassung

Naloxon wird beschuldigt, ein Lungenödem auslösen zu können. Es wird von einem Patienten berichtet, der nach Gabe von Naloxon im Rahmen einer laparoskopischen Splenektomie ein Lungenödem entwickelte. Der klinische Verlauf wird mit den Verläufen anderer nichtkardiogener Lungenödeme verglichen. Es bleibt Unsicherheit über den zugrunde liegenden pathophysiologischen Prozess und wahren Einfluss von Naloxon auf die Entstehung eines Lungenödems.

Abstract

A case of pulmonary edema after the administration of naloxone for laparoscopic splenectomy is reported. Previous reports of naloxone-induced pulmonary edema are listed and reviewed. The clinical course is compared to other forms of non-cardiogenic pulmonary edema. Uncertainty remains about the underlying pathophysiological process and the true impact of naloxone on the development of pulmonary edema.

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Authors and Affiliations

  1. Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Regensburg, Deutschland

    C.L. Lassen, C.H.R. Wiese & B.M. Graf

  2. Klinik für Anästhesiologie und operative Intensivmedizin, Klinikum Ludwigshafen, Ludwigshafen, Deutschland

    W. Zink

  3. Klinik für Anaesthesiologie, Operative Intensivmedizin und Schmerztherapie, Marienhospital, Gelsenkirchen, Deutschland

    C. Wiesenack

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  1. C.L. Lassen
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  2. W. Zink
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  3. C.H.R. Wiese
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  5. C. Wiesenack
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Correspondence to C.L. Lassen.

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Lassen, C., Zink, W., Wiese, C. et al. Naloxoninduziertes Lungenödem. Anaesthesist 61, 129–136 (2012). https://doi.org/10.1007/s00101-012-1982-8

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  • DOI: https://doi.org/10.1007/s00101-012-1982-8

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