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Prämedikationsvisite

Kosten sparen auf Kosten des Patienten?

Premedication visits

Economising at the cost of the patient?

  • Trends und Medizinökonomie
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Zusammenfassung

Mit der Zunahme des Lebensalters ist für Patienten die Zunahme eines Operationsrisikos verbunden. Daher müssen Risikopatienten frühzeitig identifiziert sowie einer perioperativen Diagnostik und Therapie kardialer Vorerkrankungen zugeführt werden. Hierzu existieren Risikoindizes (Goldman-Score, Eagle-Kriterien) und Richtlinien der American Heart Association (AHA/ACC). Grundlage ist die Einstufung des Patienten anhand des Operationsrisikos und der Vorerkrankungen. Wird eine weitere, häufig invasive Therapie geplant, so ist der Zeitraum, um den die Operation verschoben werden kann, entscheidend. Zum Nachweis kardialer Risikoreduktion müssen extrakardiale Operationen um mindestens 3 Monate verschoben werden. Ist dieser Zeitraum nicht einzuhalten, kann eine Risikominimierung in vielen Fällen durch eine β-Blocker-Therapie erreicht werden. Eine Arbeitsgruppe des Marburger Klinikums hat zu diesem Thema eigene Lösungsstrategien entwickelt, die im Folgenden ausgeführt werden.

Abstract

The older the patient, the higher the risk of perioperative cardiac complications. Therefore, patients at risk have to be identified and the appropriate diagnostic or therapeutic measures initiated. The most important factor in this context is whether a planned surgery can be postponed. Several strategies have been developed (e.g. Goldman index, Eagle criteria) and the American Heart Association (AHA/ACC) has produced guidelines concerning perioperative diagnosis and therapy of cardiac risk patients. The common goal of these strategies is always the risk classification of the patient by combining the operative risk and the risk factors of the patient. The further procedure (diagnostic or therapeutic measures) is based on the risk classification. If further invasive therapy proves to be necessary, the determining factor is the period of time for which the operation can be delayed. This appears to be about 3 months but if this is not possible the outcome could be improved with a β-blocker therapy in advance. A working group from the university hospital in Marburg has developed a strategy for risk classification and further diagnostic and therapeutic measures as outlined in this article.

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Literatur

  1. Ashton CM, Petersen NJ, Wray NP et al. (1993) The incidence of perioperative myocardial infarction in men undergoing noncardiac surgery. Ann Intern Med 1118:504–510

    Google Scholar 

  2. Baron JF, Mundler O, Bertrand M et al. (1994) Dipyridamol-thallium-scintigraphy and gated radionuclide angiography to assess cardiac risk before abdominal aortic surgery. N Engl J Med 330:663–669

    Article  CAS  PubMed  Google Scholar 

  3. Boersma E, Poldermans D, Bax JJ et al. (2001) Predictors of cardiac events after major vascular surgery. Role of clinical characteristics, dobutamine echocardiography, and beta-blocker therapy. JAMA 285:1865–1873

    Article  CAS  PubMed  Google Scholar 

  4. Bronson D, Halperin A, Marwick T (1995) Evaluating cardiac risk in noncardiac surgery patients. Cleve Clin J Med 62:391–400

    CAS  PubMed  Google Scholar 

  5. Brown KA, Rowen M (1993) Extent of jeopardized viable myocardium determined by myocardial perfusion imaging best predicts perioperative cardiac events in patients undergoing noncardiac surgery. J Am Coll Cardiol 21:325–330

    CAS  PubMed  Google Scholar 

  6. Bry JD, Belkin M, O’Donell TF Jr et al. (1994) An assessment of the positive predictive value and cost-effectiveness of dipyridamole myocardial scintigraphy in patients undergoing vascular surgery. J Vasc Surg 19:112–124

    CAS  PubMed  Google Scholar 

  7. Chassot PG, Delabays A, Spahn DR (2002) Preoperative evaluation of patients with, or at risk of, coronary artery disease undergoing noncardiac surgery. Br J Anaesth 89:747–759

    Article  PubMed  Google Scholar 

  8. Detsky AS, Abrams HB, McLaughlin JR et al. (1986) Predicting cardiac complications in patients undergoing non-cardiac surgery. J Gen Intern Med 1:211–219

    CAS  PubMed  Google Scholar 

  9. Eagle KA, Coley CM, Newell JB et al. (1989) Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery. Ann Intern Med 110:859–866

    Google Scholar 

  10. Eagle KA, Rihal CS, Mickel MC, Holmes DR, Foster ED, Gersh BJ (1997) Cardiac risk of noncardiac surgery: influence of coronary disease and type of surgery in 3,368 operations. CASS Investigators and University of Michigan Heart care program. Coronary artery surgery study. Circulation 96:1882–1887

    CAS  PubMed  Google Scholar 

  11. Eagle KA, Berger PB, Calkins H et al. (2002) ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery—executive summary. Circulation 105:1257–1267

    Google Scholar 

  12. Eichelberger JP, Schwarz KQ, Black ER, Green RM, Ouriel K (1993) Predictive value of dobutamine stress echocardiography just before noncardiac vascular surgery. Am J Cardiol 72:602–607

    Article  CAS  PubMed  Google Scholar 

  13. Foster ED, Davis KB, Carpentier JA, Abele S, Fray D (1986) Risk of noncardiac operation in patients with defined coronary artery disease: The Coronary Artery Surgery Study (CASS) registry experience. Ann Thorac Surg 41:42–50

    CAS  PubMed  Google Scholar 

  14. Gauss A, Röhm HJ, Schäuffelen A et al. (2001) Electro-cardiographic exercise stress testing for cardiac risk assessment in patients undergoing noncardiac surgery. Anesthesiology 94:38–46

    Article  CAS  PubMed  Google Scholar 

  15. Gilbert K, Larocque BJ, Patrick LT (2000) Prospective evaluation of cardiac risk indices for patients undergoing noncardiac surgery. Ann Intern Med 133:356–359

    CAS  PubMed  Google Scholar 

  16. Goldman L, Caldera D, Nussbaum S et al. (1977) Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med 297:845–850

    CAS  PubMed  Google Scholar 

  17. Halm EA, Browner WS, Tubau JF, Tateo IM, Mangano DT (1996) Echocardiography for assessing cardiac risk in patients having noncardiac surgery. Ann Intern Med 125:433–441

    CAS  PubMed  Google Scholar 

  18. Hendel RC, Whitfield SS, Villegas BJ et al. (1992) Prediction of late cardiac events by dipyramidole thallium imaging in patients undergoing elective vascular surgery. Am J Cardiol 70:1243–1249

    CAS  PubMed  Google Scholar 

  19. Hertzer NR (1987) Basic data concerning coronary disease in peripheral vascular patients. Ann Vasc Surg 1:616–620

    CAS  PubMed  Google Scholar 

  20. Kaluza GL, Joseph J, Lee JR, Raizner ME, Raizner AE (2000) Catastrophic outcomes of noncardiac surgery soon after coronary stenting. J Am Coll Cardiol 35:1288–1294

    Article  CAS  PubMed  Google Scholar 

  21. Khuri SF, Daley J, Henderson W et al. (1995) The National Veterans Administration Surgical Risk Study: risk adjustment for the comparative assessment of the quality of surgical care. J Am Coll Surg 180:519–531

    CAS  PubMed  Google Scholar 

  22. Krone RJ, Laskey WK, Johnson C, Kimmel SE et al. (2000) A simplified lesion classification for predicting success and complications of coronary angioplasty. Am J Cardiol 85:1179–1184

    Article  CAS  PubMed  Google Scholar 

  23. Landesberg G, Einav S, Christopherson R et al. (1997) Perioperative ischemia and cardiac complications in major vascular surgery: importance of the perioperative twelve-lead electrocardiogram. J Vasc Surg 26:570–578

    CAS  PubMed  Google Scholar 

  24. Larsen SF, Oelsen KH, Jacobsen E et al. (1987) Prediction of cardiac risk in noncardiac surgery. Eur Heart J 8:179–185

    CAS  PubMed  Google Scholar 

  25. Laskey WK, Kimmel SE, Krone RJ, Johnson C (2000) Contemporary trends in coronary intervention: a report from the registry of the society for cardiac angiography and interventions. Catheter Cardiovasc Interv 49:19–22

    Article  CAS  PubMed  Google Scholar 

  26. Lette J, Waters D, Bernier H et al. (1992) Preoperative and long-term cardiac risk assessment. Predictive value of 23 clinical descriptors, 7 multivariate scoring systems, and quantitative dipyridamole imaging in 360 patients. Ann Surg 216:192–204

    CAS  PubMed  Google Scholar 

  27. Lette J, Waters D, Cerino M et al. (1992) Preoperative coronary artery disease risk stratification based on dipyramidole imaging, and a simple three-step, three-segment model for patients undergoing noncardiac vascular surgery or major general surgery. Am J Cardiol 69:1553–1558

    CAS  PubMed  Google Scholar 

  28. Mangano DT (1990) Perioperative cardiac morbidity. Anesthesiology 72:153–184

    CAS  PubMed  Google Scholar 

  29. Mangano DT, Goldman L (1995) Preoperative assessment of patients with known or suspected coronary artery disease. N Engl J Med 333:1750–1756

    Article  CAS  PubMed  Google Scholar 

  30. Mangano DT, Browner WS, Hollenberg M et al. (1990) Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. N Engl J Med 323:1781–1788

    CAS  PubMed  Google Scholar 

  31. Mangano DT, Wong MG, London MJ et al. (1991) Perioperative myocardial ischemia in patients undergoing noncardiac surgery—II: Incidence and severity during the first week after surgery. J Am Coll Cardiol 17:851–857

    CAS  PubMed  Google Scholar 

  32. Mangano DT, Layug EI, Wallace A, Tateo I (1996) Multicenter study of Perioperative Ischemia Research Group. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. N Engl J Med 335:1713–1720

    Article  CAS  PubMed  Google Scholar 

  33. Mantha S (2000) Rational cardiac risk stratification before peripheral vascular surgery: application of evidence-based medicine and Bayesian analysis. Semin Cardiothorac Vasc Anesth 4:198–212

    Google Scholar 

  34. Mantha S, Roizen MF, Barnard J, et al. (1994) Relative effectiveness of four preoperative tests for predictive adverse cardiac outcome after vascular surgery. Anesth Analg 79:422–433

    CAS  PubMed  Google Scholar 

  35. McCann RL, Wolfe WG (1989) Resection of abdominal aortic aneurysm in patients with low ejection fraction. J Vasc Surg 10:240–244

    Article  CAS  PubMed  Google Scholar 

  36. McFalls EO, Doliszny KM, Grund F et al. (1993) Angina and persistent exercise thallium defects: independent risk factors in elective vascular surgery. J Am Coll Cardiol 21:1347–1352

    CAS  PubMed  Google Scholar 

  37. Nishina K, Mikawa K, Uesugi T et al. (2002) Efficacy of clonidine for prevention of perioperative myocardial ischemia: a critical approach and meta-analysis of literature. Anesthesiology 96:323–329

    Article  CAS  PubMed  Google Scholar 

  38. Palda VA, Detsky AS (1997) Perioperative assessment and management of risk from coronary artery disease. Ann Intern Med 127:313–328

    CAS  PubMed  Google Scholar 

  39. Pasternak P, Grossi E, Baumann G et al. (1989) The value of silent myocardial ischemia monitoring in the prediction of perioperative myocardial infarction in patients undergoing peripheral vascular surgery. J Vasc Surg 10:617–625

    Article  PubMed  Google Scholar 

  40. Paul SD, Eagle KA, Kuntz KM et al. (1996) Concordance of preoperative clinical risk with angiographic severity of coronary artery disease in patients undergoing vascular surgery. Circulation 94:1561–1566

    CAS  PubMed  Google Scholar 

  41. Poldermans D, Arnese M, Fioretti P et al. (1995) Improved cardiac risk stratification in major vascular surgery with dobutamine-atropine stress echocardiography. J Am Coll Cardiol 26:648–653

    Article  CAS  PubMed  Google Scholar 

  42. Poldermans D, Boersma E, Bax JJ et al. (1999) Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery. N Engl J Med 341:1789–1794

    Article  CAS  PubMed  Google Scholar 

  43. Posner KL, Norman GA van, Chan V (1999) Adverse cardiac outcomes after noncardiac surgery in patients with prior percutaneous transluminal coronary angioplasty. Anesth Analg 89:553–560

    CAS  PubMed  Google Scholar 

  44. Raby KE, Goldman L, Creager MA et al. (1989) Correlation between preoperative ischemia and major cardiac events after peripheral vascular surgery. N Engl J Med 321:1296–1300

    CAS  PubMed  Google Scholar 

  45. Raby KE, Brull SJ, Timimi F et al. (1999) The effect of heart rate control on myocardial ischemia among high risk patients after vascular surgery. Anesth Analg 88:477–482

    CAS  PubMed  Google Scholar 

  46. Schein OD, Katz J, Bass EB et al. (2000) The value of routine preoperative medical testing before cataract surgery. N Engl J Med 342:168–175

    Article  CAS  PubMed  Google Scholar 

  47. Shah KB, Kleinman BS, Rao TLK et al. (1990) Angina and other risk factors in patients with cardiac diseases undergoing noncardiac operations. Anesth Analg 70:240–247

    CAS  PubMed  Google Scholar 

  48. Shaw LJ, Eagle KA, Gersh BJ, Miller DD (1996) Meta-analysis of intravenous dipyridamole thallium-201 imaging (1985 to 1994) and dobutamine stress echocardiography (1991 to 1994) for risk stratification before vascular surgery. J Am Coll Cardiol 27:787–798

    Article  CAS  PubMed  Google Scholar 

  49. Tresch D (1995) Diagnostic and prognostic value of ambulatory electrographic monitoring in older patients. J Am Geriatr Soc 43:66–70

    CAS  PubMed  Google Scholar 

  50. Vanzetto G, Machecourt J, Blendea D et al. (1996) Additive value of thallium single-photon emission computed tomography myocardial imaging for prediction of perioperative events in clinically selected high cardiac risk patients having abdominal aortic surgery. Am J Cardiol 77:143–148

    CAS  PubMed  Google Scholar 

  51. Wallace A, Layug B, Tateo I et al. (1998) Prophylactic atenolol reduces postoperative myocardial ischemia. Anesthesiology 88:7–17

    Article  CAS  PubMed  Google Scholar 

  52. Younis L, Stratmann H, Takase B et al. (1994) Preoperative clinical assessment and dipyridamole thallium-210 scintigraphy for prediction and prevention of cardiac events in patients having major noncardiovascular surgery and known or suspected coronary artery disease. Am J Cardiol 1994; 74:311–317

    Google Scholar 

  53. Zeldin RA (1984) Assessing cardiac risk in patients who undergo noncardiac surgical procedures. Can J Surg 27:402–404

    CAS  PubMed  Google Scholar 

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Kratz, C.D., Christ, M., Maisch, B. et al. Prämedikationsvisite. Anaesthesist 53, 862–870 (2004). https://doi.org/10.1007/s00101-004-0709-x

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