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Prädiktive Biomarker beim Prostatakarzinom

Androgenrezeptor-Spleißvariante AR-V7: Implikationen für die Praxis

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Mittlerweile stehen verschiedene Therapeutika zur Behandlung des metastasierten kastrationsresistenten Prostatakarzinoms zur Verfügung. Allen gemeinsam ist, dass das Ansprechen des Patienten und auch die Dauer des Ansprechens auf die verschiedenen Therapeutika, bisher nicht vorausgesagt werden kann. Ein geeigneter prädiktiver Biomarker, der dieses Problem löst, wird gesucht. Dabei wird auch die Androgenrezeptor-Spleißvariante AR-V7 als Option gehandelt.

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Steinestel, J. Androgenrezeptor-Spleißvariante AR-V7: Implikationen für die Praxis. Uro-News 21, 22–26 (2017). https://doi.org/10.1007/s00092-017-1482-x

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  • DOI: https://doi.org/10.1007/s00092-017-1482-x

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