Abstract
Purpose
Hybrid operating rooms benefit patients with severe trauma but have a prerequisite of significant resources. This paper proposes a practical triage method to determine patients that should enter the hybrid operating room considering a limited availability of medical resources.
Methods
This retrospective observational study was conducted using the database from the Japan Trauma Data Bank comprising information collected between January 2004 and December 2018. A machine-learning-based triage algorithm was developed using the baseline demographics, injury mechanisms, and vital signs obtained from the database. The analysis dataset comprised information regarding 117,771 trauma patients with an abbreviated injury scale (AIS) > 3. The performance of the proposed model was compared against those of other statistical models [logistic regression and classification and regression tree (CART) models] while considering the status quo entry condition (systolic blood pressure < 90 mmHg).
Results
The proposed trauma hybrid-suite entry algorithm (THETA) outperformed other pre-existing algorithms [precision–recall area under the curve: THETA (0.59), logistic regression model (0.22), and classification and regression tree (0.20)].
Conclusion
A machine-learning-based algorithm was developed to triage patient entry into hybrid operating rooms. Although the validation in a prospective multicentre arrangement is warranted, the proposed algorithm could be a potentially useful tool in clinical practice.
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Data availability
No data are available for sharing.
References
Kirkpatrick AW, Vis C, Dubé M, Biesbroek S, Ball CG, Laberge J, Shultz J, Rea K, Sadler D, Holcomb J, Koretbeek J. The evolution of a purpose designed hybrid trauma operating room from the trauma service perspective: the RAPTOR (resuscitation with angiography percutaneous treatments and operative resuscitations). Injury. 2014;45:1413–21. https://doi.org/10.1016/j.injury.2014.01.021.
Cooke BM, Mohandas N, Coppel RL. Malaria and the red blood cell membrane. Semin Hematol. 2004;41:173–88. https://doi.org/10.1053/j.seminhematol.2004.01.004.
Ball CG, Kirkpatrick AW, D’Amours SK. The RAPTOR: resuscitation with angiography, percutaneous techniques and operative repair. Transforming the discipline of trauma surgery. Can J Surg. 2011;54:E3–4.
Pryor JP, Braslow B, Reilly PM, Gullamondegi O, Hedrick JH, Schwab CW. The evolving role of interventional radiology in trauma care. J Trauma. 2005;59:102–4. https://doi.org/10.1097/01.ta.0000171455.66437.de.
Brenner M, Inaba K, Aiolfi A, DuBose J, Fabian T, Bee T, Holcomb JB, Moore L, Skarupa D, Scalea TM. Resuscitative endovascular balloon occlusion of the aorta and resuscitative thoracotomy in select patients with hemorrhagic shock: early results from the American association for the surgery of trauma’s aortic occlusion in resuscitation for trauma and acute care surgery registry. J Am Coll Surg. 2018;226:730–40. https://doi.org/10.1016/j.jamcollsurg.2018.01.044.
Carver D, Kirkpatrick AW, D’Amours S, Hameed SM, Beveridge J, Ball CG. A prospective evaluation of the utility of a hybrid operating suite for severely injured patients: overstated or underutilized? Ann Surg. 2020;271:958–61. https://doi.org/10.1097/SLA.0000000000003175.
Kinoshita T, Yamakawa K, Matsuda H, Yoshikawa Y, Wada D, Hamasaki T, Kota O, Yasushi N, Satoshi F. The survival benefit of a novel trauma workflow that includes immediate whole-body computed tomography, surgery, and interventional radiology, all in one trauma resuscitation room: a retrospective historical control study. Ann Surg. 2019;269:370–6. https://doi.org/10.1097/SLA.0000000000002527.
Fehr A, Beveridge J, DʼAmours SD, Kirkpatrick AW, Ball CG. The potential benefit of a hybrid operating environment among severely injured patients with persistent hemorrhage: how often could we get it right? J Trauma Acute Care Surg. 2016;80:457–60. https://doi.org/10.1097/TA.0000000000000951.
Martin M, Izenberg S, Cole F, Bergstrom S, Long W. A decade of experience with a selective policy for direct to operating room trauma resuscitations. Am J Surg. 2012;204:187–92. https://doi.org/10.1016/j.amjsurg.2012.06.001.
Fischer RP, Jelense S, Perry JF Jr. Direct transfer to operating room improves care of trauma patients. A simple, economically feasible plan for large hospitals. JAMA. 1978;240:1731–2.
Saleh AM, Arashi M, Kibria BG. Theory of ridge regression estimation with applications. Hoboken: Wiley; 2019.
Chen T, Guestrin C. XGBoost: a scalable tree boosting system. In: Proceedings of the 22nd ACM SIGKDD international conference on knowledge discovery and data mining; 2016;785–94
Hinton GE. Connectionist learning procedures. Artif Intell. 1989;40:185–234. https://doi.org/10.1016/0004-3702(89)90049-0.
Cawley G, Talbot N. Sparse Bayesian learning and the relevance multi-layer perceptron network. In: Proceedings of the 2005 IEEE international joint conference on neural networks.2005;2:1320–4
Forgey EW. Cluster analysis of multivariate data: efficiency versus interpretability of classification. Biometrics. 1965;21:768–9.
Pavlyshenko B. Using stacking approaches for machine learning models. In: IEEE second international conference on data stream mining & processing (DSMP) 2018;255–8
Pearl R, Reed LJ, Kish JF. The logistic curve and the census count of 1940. Science. 1940;92:486–8. https://doi.org/10.1126/science.92.2395.486.
Hosmer DW, Lemeshow S. Applied logistic regression. New York: Wiley; 1989.
Breiman L, Friedman JH, Stone CJ, Olshen RA. Classification and regression trees. Boca Raton: CRC Press; 1984.
Saito T, Rehmsmeier M. The precision-recall plot is more informative than the ROC plot when evaluating binary classifiers on imbalanced datasets. PLoS ONE. 2015;10:e0118432. https://doi.org/10.1371/journal.pone.0118432.
Acknowledgements
We would like to thank Editage (http://www.editage.com) for English language editing.
Funding
The study was funded by Japan Society for the Promotion of Science (Grant No. 21K16585).
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AS and EA contributed to the acquisition of data, while AS, EA, and TK jointly conceived of and designed this study. AS and TK jointly analysed and interpreted the data; EA confirmed the analysis, whereas EA and YO drafted the manuscript. All authors reviewed and discussed the manuscript. EA and TK revised the manuscript for important intellectual content. All the authors read and approved the final manuscript.
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68_2022_2002_MOESM1_ESM.pdf
Supplementary file1 Supplementary file1 Supplemental Fig. 1 Schematic of the proposed machine-learning model (PDF 99 KB)
Supplementary file3 Supplemental Movie Screen recording demonstrating use of the proposed web application (MOV 6535 KB)
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Senda, A., Endo, A., Kinoshita, T. et al. Development of practical triage methods for critical trauma patients: machine-learning algorithm for evaluating hybrid operation theatre entry of trauma patients (THETA). Eur J Trauma Emerg Surg 48, 4755–4760 (2022). https://doi.org/10.1007/s00068-022-02002-0
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DOI: https://doi.org/10.1007/s00068-022-02002-0