Literatur
Verma V, Cushman TR, Tang C, Welsh JW (2018) Toxicity of radiation and immunotherapy combinations. Adv Radiat Oncol 3(4):506–511
Martin AM, Cagney DN, Catalano PJ, Alexander BM, Redig AJ, Schoenfeld JD, Aizer AA (2018) Immunotherapy and symptomatic radiation necrosis in patients with brain metastases treated with stereotactic radiation. JAMA Oncol 4(8):1123–1124
Shaverdian N, Lisberg AE, Bornazyan K, Veruttipong D, Goldman JW, Formenti SC, Garon EB, Lee P (2017) Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial. Lancet Oncol 18(7):895–903
Antonia SJ, Villegas A, Daniel D, Vicente D, Murakami S, Hui R, Yokoi T, Chiappori A, Lee KH, de Wit M, Cho BC, Bourhaba M, Quantin X, Tokito T, Mekhail T, Planchard D, Kim YC, Karapetis CS, Hiret S, Ostoros G, Kubota K, Gray JE, Paz-Ares L, de Castro Carpeño J, Wadsworth C, Melillo G, Jiang H, Huang Y, Dennis PA, Özgüroğlu M, PACIFIC Investigators (2017) Durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer. N Engl J Med 377(20):1919–1929
Kelly RJ, Ajani JA, Kuzdzal J, Zander T, Van Cutsem E, Piessen G, Mendez G, Feliciano J, Motoyama S, Lièvre A, Uronis H, Elimova E, Grootscholten C, Geboes K, Zafar S, Snow S, Ko AH, Feeney K, Schenker M, Kocon P, Zhang J, Zhu L, Lei M, Singh P, Kondo K, Cleary JM, Moehler M, CheckMate 577 Investigators (2021) Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer. N Engl J Med 384(13):1191–1203
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Interessenkonflikt
L. Seiß und T. Brunner geben an, dass kein Interessenkonflikt besteht.
Rights and permissions
About this article
Cite this article
Seiß, L., Brunner, T. Nebenwirkungsprofil einer frühen Immuntherapie nach Radiotherapie: eine gepoolte Analyse von Studien in der Datenbank der US Food and Drug Administration. Strahlenther Onkol 198, 1049–1051 (2022). https://doi.org/10.1007/s00066-022-01995-2
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00066-022-01995-2