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Einfluss der körperlichen Aktivität vor, während und nach der Chemotherapie auf die kognitive Leistungsfähigkeit bei Patientinnen mit Mammakarzinom: Ergebnisse einer prospektiven US-amerikanischen Studie

Impact of physical activity before, during, and after chemotherapy on cognitive functions in patients with breast cancer: results of a prospective US study

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Abbreviations

KA:

Körperliche Aktivität

KL:

Kognitive Leistungsfähigkeit

FACT-Cog:

„Functional Assessment of Cancer Therapy – Cognitive Function“, erfasst die subjektiv empfundene kognitive Leistung

RVP:

„Rapid visual processing“, erfasst die Konzentrationsfähigkeit

DMS:

„Delayed match-to-sample“, erfasst das visuelle Erinnerungsvermögen

Literatur

  1. Salerno EA, Culakova E, Kleckner AS, Heckler CE, Lin PJ, Matthews CE, Conlin A, Weiselberg L, Mitchell J, Mustian KM, Janelsins MC (2021) Physical activity patterns and relationships with cognitive function in patients with breast cancer before, during, and after chemotherapy in a prospective, nationwide study. J Clin Oncol 39(29):3283–3292. https://doi.org/10.1200/JCO.20.03514

    Article  CAS  PubMed  Google Scholar 

  2. Janelsins MC, Heckler CE, Peppone LJ, Kamen C, Mustian KM, Mohile SG, Magnuson A, Kleckner IR, Guido JJ, Young KL, Conlin AK, Weiselberg LR, Mitchell JW, Ambrosone CA, Ahles TA, Morrow GR (2017) Cognitive complaints in survivors of breast cancer after chemotherapy compared with age-matched controls: an analysis from a nationwide, multicenter, prospective longitudinal study. J Clin Oncol 35(5):506–514. https://doi.org/10.1200/jco.2016.68.5826

    Article  PubMed  Google Scholar 

  3. Janelsins MC, Heckler CE, Peppone LJ, Ahles TA, Mohile SG, Mustian KM, Palesh O, O’Mara AM, Minasian LM, Williams AM, Magnuson A, Geer J, Dakhil SR, Hopkins JO, Morrow GR (2018) Longitudinal trajectory and characterization of cancer-related cognitive impairment in a nationwide cohort study. J Clin Oncol 36(32):JCO2018786624. https://doi.org/10.1200/jco.2018.78.6624

    Article  CAS  Google Scholar 

  4. Wagner MA, Erickson KI, Bender CM, Conley YP (2020) The influence of physical activity and epigenomics on cognitive function and brain health in breast cancer. Front Aging Neurosci 12:123. https://doi.org/10.3389/fnagi.2020.00123

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kohl HW, Paffenbarger RS et al (1997) The aerobics center longitudinal study physical activity questionnaire. Med Sci Sports Exerc 29:S10–S14

    Google Scholar 

  6. Ainsworth BE, Haskell WL, Herrmann SD, Meckes N, Bassett DR Jr., Tudor-Locke C, Greer JL, Vezina J, Whitt-Glover MC, Leon AS (2011) 2011 compendium of physical activities: a second update of codes and MET values. Med Sci Sports Exerc 43(8):1575–1581. https://doi.org/10.1249/MSS.0b013e31821ece12

    Article  PubMed  Google Scholar 

  7. Tudor-Locke C, Washington TL, Ainsworth BE, Troiano RP (2009) Linking the American time use survey (ATUS) and the compendium of physical activities: methods and rationale. J Phys Act Health 6(3):347–353. https://doi.org/10.1123/jpah.6.3.347

    Article  PubMed  Google Scholar 

  8. Piercy KL, Troiano RP, Ballard RM, Carlson SA, Fulton JE, Galuska DA, George SM, Olson RD (2018) The physical activity guidelines for americans. JAMA 320(19):2020–2028. https://doi.org/10.1001/jama.2018.14854

    Article  PubMed  Google Scholar 

  9. Wagner LI, Sweet J, Butt Z et al (2009) Measuring patient self-reported cognitive function: development of the functional assessment of cancer therapy—cognitive function instrument. J Support Oncol 7:W32–W39

    Google Scholar 

  10. Fray PJ, Robbins TW (1996) CANTAB battery: proposed utility in neurotoxicology. Neurotoxicol Teratol 18(4):499–504. https://doi.org/10.1016/0892-0362(96)00027-x

    Article  CAS  PubMed  Google Scholar 

  11. Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P (1994) Cambridge neuropsychological test automated battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia 5(5):266–281. https://doi.org/10.1159/000106735

    Article  CAS  PubMed  Google Scholar 

  12. Wilkinson GS, Robertson GJ (2006) WRAT 4: wide range achievement test

    Google Scholar 

  13. Spielberger C, Sydeman S, Owen A et al (1999) Measuring anxiety and anger with the state-trait anxiety inventory (STAI) and the state-trait anger expression inventory (STAXI). Lawrence Erlbaum, Mahwah, NJ

    Google Scholar 

  14. Mendoza TR, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK, Huber SL (1999) The rapid assessment of fatigue severity in cancer patients: use of the brief fatigue inventory. Cancer 85(5):1186–1196. https://doi.org/10.1002/(sici)1097-0142(19990301)85:5〈1186::aid-cncr24〉3.0.co;2‑n

    Article  CAS  Google Scholar 

  15. Janelsins MC, Mustian KM, Palesh OG, Mohile SG, Peppone LJ, Sprod LK, Heckler CE, Roscoe JA, Katz AW, Williams JP, Morrow GR (2012) Differential expression of cytokines in breast cancer patients receiving different chemotherapies: implications for cognitive impairment research. Support Care Cancer 20(4):831–839. https://doi.org/10.1007/s00520-011-1158-0

    Article  PubMed  Google Scholar 

  16. Kesler SR, Blayney DW (2016) Neurotoxic effects of anthracycline- vs nonanthracycline-based chemotherapy on cognition in breast cancer survivors. JAMA Oncol 2(2):185–192. https://doi.org/10.1001/jamaoncol.2015.4333

    Article  PubMed  PubMed Central  Google Scholar 

  17. Cheung YT, Foo YL, Shwe M, Tan YP, Fan G, Yong WS, Madhukumar P, Ooi WS, Chay WY, Dent RA, Ang SF, Lo SK, Yap YS, Ng R, Chan A (2014) Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: cognitive function (FACT-Cog) in breast cancer patients. J Clin Epidemiol 67(7):811–820. https://doi.org/10.1016/j.jclinepi.2013.12.011

    Article  PubMed  Google Scholar 

  18. Costa DSJ, Fardell JE (2019) Why are objective and perceived cognitive function weakly correlated in patients with cancer? J Clin Oncol 37(14):1154–1158. https://doi.org/10.1200/JCO.18.02363

    Article  PubMed  Google Scholar 

  19. Brunt AM, Haviland JS, Kirby AM, Somaiah N, Wheatley DA, Bliss JM, Yarnold JR (2021) Five-fraction radiotherapy for breast cancer: FAST-forward to implementation. Clin Oncol 33(7):430–439. https://doi.org/10.1016/j.clon.2021.04.016

    Article  CAS  Google Scholar 

  20. Bakoyiannis I, Tsigka EA, Perrea D, Pergialiotis V (2016) The impact of endocrine therapy on cognitive functions of breast cancer patients: a systematic review. Clin Drug Investig 36(2):109–118. https://doi.org/10.1007/s40261-015-0364-9

    Article  CAS  PubMed  Google Scholar 

  21. Ning S, Qiao K, Pan L (2022) Physical activity patterns and cognitive function in patients with breast cancer. J Clin Oncol. https://doi.org/10.1200/JCO.21.02073

    Article  PubMed  Google Scholar 

  22. Treanor CJ, McMenamin UC, O’Neill RF, Cardwell CR, Clarke MJ, Cantwell M, Donnelly M (2016) Non-pharmacological interventions for cognitive impairment due to systemic cancer treatment. Cochrane Database Syst Rev 8:CD11325. https://doi.org/10.1002/14651858.CD011325.pub2

    Article  Google Scholar 

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Authors and Affiliations

  1. Universitätsklinik für Radiotherapie und Radioonkologie, Landeskrankenhaus Salzburg, Paracelsus Medizinische Privatuniversität, Müllner Hauptstraße 48, 5020, Salzburg, Österreich

    Gerd Fastner MSc &  F. Zehentmayr MSc, MSc

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  1. Gerd Fastner MSc
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  2. F. Zehentmayr MSc, MSc
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Corresponding author

Correspondence to Gerd Fastner MSc.

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Interessenkonflikt

G. Fastner deklariert Honorare für Vorträge von Roche und F. Zehentmayr deklariert, Vortragshonorare von AstraZeneca erhalten zu haben.

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Originalpublikation

Salerno EA, Culakova E, Kleckner AS et al (2022) Physical activity patterns and relationships with cognitive functions in patients with breast cancer before, during, and after chemotherapy in a prospective, nationwide study. JCO 39:3283–3292.

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Fastner, G., Zehentmayr, F. Einfluss der körperlichen Aktivität vor, während und nach der Chemotherapie auf die kognitive Leistungsfähigkeit bei Patientinnen mit Mammakarzinom: Ergebnisse einer prospektiven US-amerikanischen Studie. Strahlenther Onkol 198, 670–673 (2022). https://doi.org/10.1007/s00066-022-01934-1

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