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Virtuelle Prostatektomie mit einer ultrahoch dosierten Single-dose-Strahlentherapie

Virtual prostatectomy using single dose radiotherapy

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Literatur

  1. Brand DH, Tree AC, Ostler P et al (2019) Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial. Lancet Oncol 20(11):1531–1543. https://doi.org/10.1016/S1470-2045(19)30569-8

    Article  PubMed  PubMed Central  Google Scholar 

  2. Zilli T, Franzese C, Bottero M et al (2019) Single fraction urethra-sparing prostate cancer SBRT: phase I results of the ONE SHOT trial. Radiother Oncol 139:83–86. https://doi.org/10.1016/j.radonc.2019.07.018

    Article  PubMed  Google Scholar 

  3. Morton G, Mcguffin M, Chung HT et al (2020) Prostate high dose-rate brachytherapy as monotherapy for low and intermediate risk prostate cancer: efficacy results from a randomized phase II clinical trial of one fraction of 19 Gy or two fractions of 13.5 Gy. Radiother Oncol 146:90–96. https://doi.org/10.1016/j.radonc.2020.02.009

    Article  CAS  PubMed  Google Scholar 

  4. Gomez-iturriaga A, Buchser D, Mayrata E et al (2020) Pattern of relapse and dosimetric analysis of a single dose 19 Gy HDR-brachytherapy phase II trial. Radiother Oncol 146:16–20. https://doi.org/10.1016/j.radonc.2020.01.025

    Article  CAS  PubMed  Google Scholar 

  5. Dearnaley D, Syndikus I, Mossop H et al (2016) Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5‑year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial. Lancet Oncol 17(8):1047–1060. https://doi.org/10.1016/S1470-2045(16)30102-4

    Article  PubMed  PubMed Central  Google Scholar 

  6. Tharmalingam H, Tsang Y, Ostler P, Wylie J, Bahl A, Lydon A (2020) Single dose high-dose rate (HDR) brachytherapy (BT) as monotherapy for localised prostate cancer: early results of a UK national cohort study. Radiother Oncol 143:95–100. https://doi.org/10.1016/j.radonc.2019.12.017

    Article  PubMed  Google Scholar 

  7. Crook JM, Tang C, Thames H et al (2020) A biochemical definition of cure after brachytherapy for prostate cancer. Radiother Oncol 149:64–69. https://doi.org/10.1016/j.radonc.2020.04.038

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Hamdy FC, Donovan JL, Lane JA et al (2016) 10-year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer. N Engl J Med 375:1415–1424. https://doi.org/10.1056/NEJMoa1606220

    Article  PubMed  Google Scholar 

  9. Donovan JL, Hamdy FC, Lane JA et al (2016) Patient-reported outcomes after monitoring, surgery, or radiotherapy for prostate. Cancer. https://doi.org/10.1056/NEJMoa1606221

    Article  PubMed  PubMed Central  Google Scholar 

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Correspondence to Mohamed Shelan.

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M. Shelan, E. Riggenbach und D. M. Aebersold geben an, dass kein Interessenkonflikt besteht.

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Originalpublikation

Greco C et al (2021) Safety and efficacy of virtual prostatectomy with single-dose radiotherapy in patients with intermediate-risk prostate cancer: results from the PROSINT phase II randomized clinical trial. JAMA Oncology. https://doi.org/10.1001/jamaoncol.2021.0039

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Shelan, M., Riggenbach, E. & Aebersold, D.M. Virtuelle Prostatektomie mit einer ultrahoch dosierten Single-dose-Strahlentherapie. Strahlenther Onkol 197, 943–945 (2021). https://doi.org/10.1007/s00066-021-01824-y

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  • DOI: https://doi.org/10.1007/s00066-021-01824-y

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