Reply to the letter to the editor “Comment to ‘Impact of postmastectomy radiotherapy on the outcomes of breast cancer patients with T1-2 N1 disease; an individual patient data analysis of three clinical trials’”
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The authors of the letter to the editor stated that my conclusions are: “Postmastectomy radiotherapy in T1-2 N1 breast cancer patients who have received modern chemotherapy drugs, does not provide any benefit for overall and disease-free survival.” In fact, my conclusions—as clarified in the abstract—are: “The current analysis does not show a beneficial impact of PMRT on overall or relapse-free survival among patients with T1–T2 N1 disease who received standard adjuvant systemic therapy. There is, however, evidence of improvement in locoregional relapse-free survivalwith PMRT.” So, the study did not tackle disease-free survival but rather relapse-free survival (which is a completely different concept). Moreover, the study did not deny some...
Conflict of interest
O. Abdel-Rahman declares that he has no competing interests.